Paraspinal Synovial Sarcoma as an Unusual Postradiation Complication in Pediatric Abdominal Neuroblastoma Journal Articles

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abstract

The development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant peripheral nerve sheath tumors, and angiosarcomas are most frequently encountered. Radiation-associated synovial sarcomas are uncommon and exceedingly rare in pediatric patients. We report an unusual case of paraspinal synovial sarcoma presenting in an adolescent female 13 years after radiation therapy for her neuroblastoma.

authors

Mullah-Ali, Ali
Ramsay, Jennifer A
Bourgeois, Jacqueline
Hodson, Ian
MacDonald, Paula
Midia, Mehran
Portwine, Carol

status

published

publication date

July 2008

has subject area

1102 Cardiorespiratory Medicine and Haematology (FoR)
Antineoplastic Combined Chemotherapy Protocols (MeSH)
Chromosomes, Human, Pair 18 (MeSH)
Chromosomes, Human, X (MeSH)
Cisplatin (MeSH)
Combined Modality Therapy (MeSH)
Cyclophosphamide (MeSH)
Dacarbazine (MeSH)
Doxorubicin (MeSH)
Etoposide (MeSH)
Female (MeSH)
Humans (MeSH)
Ifosfamide (MeSH)
Infant (MeSH)
Lumbar Vertebrae (MeSH)
Mechlorethamine (MeSH)
Muscle Neoplasms (MeSH)
Neoplasms, Radiation-Induced (MeSH)
Neoplasms, Second Primary (MeSH)
Neuroblastoma (MeSH)
Oncogene Proteins, Fusion (MeSH)
Oncology & Carcinogenesis (Science Metrix)
Remission Induction (MeSH)
Retroperitoneal Neoplasms (MeSH)
Sarcoma, Synovial (MeSH)
Spinal Stenosis (MeSH)
Translocation, Genetic (MeSH)
Vincristine (MeSH)

published in

Journal of Pediatric Hematology/Oncology Journal