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A pilot study using 99mTc to measure lead and...
Journal article

A pilot study using 99mTc to measure lead and platinum in the human kidney

Abstract

A pilot study has been conducted to investigate the hypothesis that the chemotherapeutic drug, cisplatinum, can mobilize skeletal lead. In vivo measurements of lead and platinum in the kidney of chemotherapy patients were performed with the technique of x-ray fluorescence, using 99mTc in a backscatter geometry. The results of the pilot study were inconclusive; the majority of patients exhibited no evidence of kidney lead at the level of system …

Authors

Todd AC; Chettle DR; Scott MC; Somervaille LJ; Braithwaite RA; Beaney RP; Buxton EJ

Journal

Nuclear Medicine and Biology, Vol. 20, No. 5, pp. 589–595

Publisher

Elsevier

Publication Date

July 1993

DOI

10.1016/0969-8051(93)90027-r

ISSN

0969-8051