Journal article
Energetic characteristics of cisplatin resistant ovarian carcinoma cells.
Abstract
An elevated mitochondrial membrane potential coincides with cisplatin resistance in the 2008, C13* and RH4 ovarian carcinoma cell system. Since the mitochondrial membrane potential is a component of the overall proton motive force which drive mitochondrial ATP production, we evaluated the energetic characteristics of these cells with biochemical and pharmacologic assays. Our data shows that the cisplatin resistant C13* cells have reduced …
Authors
Dorward AM; Singh G
Journal
Anticancer Research, Vol. 16, No. 1, pp. 443–447
Publication Date
1996
ISSN
0250-7005