Journal article
Urinary TIMP-2*IGFBP-7 to diagnose acute kidney injury in children receiving cisplatin
Abstract
Abstract
BackgroundCisplatin is associated with acute kidney injury (AKI) and electrolyte abnormalities. Urine tissue inhibitor of metalloproteinase 2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP-7) may be early cisplatin-AKI biomarkers.MethodsWe conducted a 12-site prospective cohort study with pediatric patients treated with cisplatin (May 2013–December 2017). Blood and urine (measured for TIMP-2, IGFBP-7) were collected …
Authors
Chui H; McMahon KR; Rassekh SR; Schultz KR; Blydt-Hansen TD; Mammen C; Pinsk M; Cuvelier GDE; Carleton BC; Tsuyuki RT
Journal
Pediatric Nephrology, Vol. 39, No. 1, pp. 269–282
Publisher
Springer Nature
Publication Date
1 2024
DOI
10.1007/s00467-023-06007-8
ISSN
0931-041X