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UNEXPECTED MOBILISATION OF LEAD DURING CISPLATIN...
Journal article

UNEXPECTED MOBILISATION OF LEAD DURING CISPLATIN CHEMOTHERAPY

Abstract

During an investigation by X-ray fluorescence of platinum uptake in the kidney after chemotherapy with cisplatin, lead was found to have accumulated in the kidney in four subjects. The average kidney lead burden in one case exceeded 800 micrograms/g. Although two of the subjects had been occupationally exposed to lead, the other two had not. The tibia lead burden was also high in the two subjects in whom it was measured. The origins of this …

Authors

El-Sharkawi AM; Cobbold S; Evans CJ; Chettle DR; Morgan WD; Jaib MBM; Somervaille LJ; Scott MC

Journal

The Lancet, Vol. 328, No. 8501, pp. 249–250

Publisher

Elsevier

Publication Date

August 1986

DOI

10.1016/s0140-6736(86)92072-6

ISSN

0140-6736