CHO Cells Concept

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• A Single Point Mutation in ϵ-COP Results in Temperature-sensitive, Lethal Defects in Membrane Transport in a Chinese Hamster Ovary Cell Mutant  Journal Articles
• A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus  Journal Articles
• Activation of the WT1 tumor suppressor gene promoter by Pea3  Journal Articles
• Adenosine‐AMP exchange activity is an integral part of the mammalian adenosine kinase  Journal Articles
• All colonies of CHO-K1 cells surviving γ-irradiation contain non-viable cells  Journal Articles
• Altered mitochondrial function and genome frequency post exposure to γ-radiation and bystander factors  Journal Articles
• Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle.  Journal Articles
• An Automated Micro-Total Immunoassay System for Measuring Cancer-Associated α2,3-linked Sialyl N-Glycan-Carrying Prostate-Specific Antigen May Improve the Accuracy of Prostate Cancer Diagnosis  Journal Articles
• An omics approach to rational feed: Enhancing growth in CHO cultures with NMR metabolomics and 2D-DIGE proteomics. - PubMed - NCBI  Journal Articles
• Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor  Journal Articles
• Bystander Effects in Repair-Deficient Cell Lines  Journal Articles
• Bystander signal production and response are independent processes which are cell line dependent  Journal Articles
• CELL SURFACE LOCALIZATION OF THE 60 kDa HEAT SHOCK CHAPERONIN PROTEIN (hsp60) IN MAMMALIAN CELLS  Journal Articles
• Changes in mitochondrial shape and distribution induced by ethacrynic acid and the transient formation of a mitochondrial reticulum  Journal Articles
• Characterization of CHO-K1 cells stably expressing PDE-IV enzymes  Journal Articles
• Characterization of a novel SCN5A genetic variant A1294G associated with mixed clinical phenotype  Journal Articles
• Characterization of full-length recombinant human Proteoglycan 4 as an ocular surface boundary lubricant  Journal Articles
• Characterization of nickel-induced mutations  Journal Articles
• Chemotherapy agents and the induction of late lethal defects.  Journal Articles
• Cloning and Characterization of cDNA for Adenosine Kinase from Mammalian (Chinese Hamster, Mouse, Human and Rat) Species.  Journal Articles
• Cloning and Some Novel Characteristics of Mitochondrial Hsp70 from Chinese Hamster Cells  Journal Articles
• Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions  Journal Articles
• Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation.  Journal Articles
• Cross-resistance to cisplatin in cells resistant to photofrin-mediated photodynamic therapy.  Journal Articles
• Cross-resistance to photofrin-mediated photodynamic therapy and UV light and recovery from photodynamic therapy damage in Rif-8A mouse fibrosarcoma cells measured using viral capacity  Journal Articles
• Dendritic cells expressing TGFβ/IL-10, and CHO cells with OX-2, increase graft survival  Journal Articles
• Development of a mathematical model for evaluating the dynamics of normal and apoptotic Chinese hamster ovary cells  Journal Articles
• Dynamin Interacts with Members of the Sumoylation Machinery  Journal Articles
• Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB  Journal Articles
• Effect of ERCC-1 overexpression on sensitivity of Chinese hamster ovary cells to DNA damaging agents.  Journal Articles
• Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents  Journal Articles
• Efficient capture of monoclonal antibody from cell culture supernatant using protein A media contained in a cuboid packed-bed device  Journal Articles
• Enhancement in amount of P1 (hsp60) in mutants of Chinese hamster ovary (CHO-K1) cells exhibiting increases in the A system of amino acid transport.  Journal Articles
• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.  Journal Articles
• G_iActivator Region of α_2A-Adrenergic Receptors: Distinct Basic Residues Mediate G_iversus G_sActivation  Journal Articles
• Gene Structure for Adenosine Kinase in Chinese Hamster and Human: High-Frequency Mutants of CHO Cells Involve Deletions of Several Introns and Exons  Journal Articles
• Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene  Journal Articles
• Heat shock protein-27 attenuates foam cell formation and atherogenesis by down-regulating scavenger receptor-A expression via NF-κB signaling  Journal Articles
• Host cell reactivation of gene expression for an adenovirus-encoded reporter gene reflects the repair of UVC-induced cyclobutane pyrimidine dimers and methylene blue plus visible light-induced 8-oxoguanine  Journal Articles
• Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants  Journal Articles
• Identification and Biochemical Studies on Novel Non-Nucleoside Inhibitors of the Enzyme Adenosine Kinase  Journal Articles
• Identification of an Expressed Truncated Form of CD200, CD200tr, which is a Physiologic Antagonist of CD200-Induced Suppression  Journal Articles
• Identification, spatial expression analysis and functional characterization of a pyrokinin-1 receptor in the Chagas’ disease vector, Rhodnius prolixus  Journal Articles
• Immunoelectron Microscopic Localization of the 60-kDa Heat Shock Chaperonin Protein (Hsp60) in Mammalian Cells  Journal Articles
• Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption  Journal Articles
• In Vivo Recognition by the Host Adaptive Immune System of Microencapsulated Xenogeneic Cells  Journal Articles
• Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives  Journal Articles
• Interrelationships of endoplasmic reticulum, mitochondria, intermediate filaments, and microtubules—a quadruple fluorescence labeling study  Journal Articles
• Intracellular events determine the fate of antithrombin Utah  Journal Articles
• Kinetic Analysis of a Unique Direct Prothrombinase, fgl2, and Identification of a Serine Residue Critical for the Prothrombinase Activity  Journal Articles
• Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues  Journal Articles
• MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis  Journal Articles
• Modeling of cell culture damage and recovery leads to increased antibody and biomass productivity in CHO cell cultures  Journal Articles
• Modeling the coupled extracellular and intracellular environments in mammalian cell culture  Journal Articles
• Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II  Journal Articles
• Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae  Journal Articles
• Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin  Journal Articles
• Mycobacterial adenosine kinase is not a typical adenosine kinase  Journal Articles
• No Evidence for Direct Activation of the Cystic Fibrosis Transmembrane Conductance Regulator by 8-Cyclopentyl-1,3-Dipropylxanthine  Journal Articles
• Oncostatin M inhibits IL-1-induced expression of IL-8 and granulocyte-macrophage colony-stimulating factor by synovial and lung fibroblasts.  Journal Articles
• Pentavalent Ions Dependency Is a Conserved Property of Adenosine Kinase from Diverse Sources:  Identification of a Novel Motif Implicated in Phosphate and Magnesium Ion Binding and Substrate Inhibition  Journal Articles
• Persistent expression of morphological abnormalities in the distant progeny of irradiated cells  Journal Articles
• Phosphorylated Derivatives That Activate or Inhibit Mammalian Adenosine Kinase Provide Insights into the Role of Pentavalent Ions in AK Catalysis  Journal Articles
• Population‐based modeling of the progression of apoptosis in mammalian cell culture  Journal Articles
• Pre-UV-Treatment of Cells Results in Enhanced Host Cell Reactivation of a UV Damaged Reporter Gene in CHO-AA8 Chinese Hamster Ovary Cells but Not in Transcription-Coupled Repair Deficient CHO-UV61 Cells  Journal Articles
• Preparative separation of monoclonal antibody aggregates by cation-exchange laterally-fed membrane chromatography  Journal Articles
• Purification and characterization of soluble forms of human and rat stem cell factor recombinantly expressed by Escherichia coli and by Chinese hamster ovary cells  Journal Articles
• Purification of humanized monoclonal antibodies by membrane-based hybrid bioseparation technique  Journal Articles
• Purification of humanized monoclonal antibody by hydrophobic interaction membrane chromatography  Journal Articles
• RESISTANCE TO PHOTODYNAMIC THERAPY IN RADIATION INDUCED FIBROSARCOMA‐1 and CHINESE HAMSTER OVARY‐MULTI‐DRUG RESISTANT CELLS in vitro  Journal Articles
• Recovery of the radiation survival-curve shoulder in CHO-KI, XRS-5 and revertant XRS-5 populations  Journal Articles
• Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys102 is the target of the redox control and essential for the catalytic activity  Journal Articles
• Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways  Journal Articles
• Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity.  Journal Articles
• Role of sphingolipids in the transport of prosaposin to the lysosomes  Journal Articles
• SIPL1 enhances the proliferation, attachment, and migration of CHO cells by inhibiting PTEN function  Journal Articles
• Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion  Journal Articles
• Structure-Activity Studies on Mammalian Adenosine Kinase  Journal Articles
• Subcellular localization of fumarase in mammalian cells and tissues  Journal Articles
• Survival, mutagenesis, and host cell reactivation in a Chinese hamster ovary cell ERCC1 knock-out mutant  Journal Articles
• Synergy in Induction of Increased Renal Allograft Survival after Portal Vein Infusion of Dendritic Cells Transduced to Express TGFβ and IL-10, along with Administration of CHO Cells Expressing the Regulatory Molecule OX-2  Journal Articles
• The Efficient Cellular Uptake of High Density Lipoprotein Lipids via Scavenger Receptor Class B Type I Requires Not Only Receptor-mediated Surface Binding but Also Receptor-specific Lipid Transfer Mediated by Its Extracellular Domain  Journal Articles
• The Heterodimeric Glycoprotein Hormone, GPA2/GPB5, Regulates Ion Transport across the Hindgut of the Adult Mosquito, Aedes aegypti  Journal Articles
• The Rodin (Research Of Determinants of INhibitor Development among PUPs with haemophilia) study: the clinical conundrum from the perspective of haemophilia treaters  Journal Articles
• The differential effects of cadmium exposure on the growth and survival of primary and established cells from fish and mammals  Journal Articles
• The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor  Journal Articles
• The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain (vol 273, pg 26343, 1998)  Journal Articles
• The influence of inorganic phosphate on the activity of adenosine kinase  Journal Articles
• The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I  Journal Articles
• Thrombospondin‐1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor‐related protein‐1 (LRP‐1)  Journal Articles
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• Ultrafast Separation and Analysis of Monoclonal Antibody Aggregates Using Membrane Chromatography  Journal Articles
• Validation of a single point flow cytometric assay for determining P-glycoprotein activity in multidrug resistant cell lines  Journal Articles
• X-irradiation- and carcinogen-induced proteins in cultured CHO cells  Journal Articles
• XRCC4's interaction with XLF is required for coding (but not signal) end joining  Journal Articles
• [1-Deamino-4-Cyclohexylalanine] Arginine Vasopressin: A Potent and Specific Agonist for Vasopressin V1b Receptors  Journal Articles