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Altered mitochondrial function and genome...
Journal article

Altered mitochondrial function and genome frequency post exposure to γ-radiation and bystander factors

Abstract

PURPOSE: To further evaluate irregular mitochondrial function and mitochondrial genome damage induced by direct γ-irradiation and bystander factors in human keratinocyte (HPV-G) epithelial cells and hamster ovarian fibroblast (CHO-K1) cells. This is as a follow-up to our recent reports of γ-irradiation-induced loss of mitochondrial function and mitochondrial DNA (mtDNA) damage. MATERIALS AND METHODS: Mitochondrial function was evaluated post …

Authors

Nugent S; Mothersill CE; Seymour C; McClean B; Lyng FM; Murphy JEJ

Journal

International Journal of Radiation Biology, Vol. 86, No. 10, pp. 829–841

Publisher

Taylor & Francis

Publication Date

October 2010

DOI

10.3109/09553002.2010.486019

ISSN

0955-3002