selected scholarly activity
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conferences
- Effects of Traffic-Related Air Pollution on Exercise Endurance, Dyspnea, and Cardiorespiratory Responses in Health and COPD. Chest. 662-675. 2022
- Cigarette smoke exposure induces diaphragm atrophy that partially regresses following cessation. The FASEB Journal. 2017
- Cigarette Smoke Exposure Generates A Unique Peroxidized Phosphatidylcholine Fingerprint In The Lung. American Journal of Respiratory and Critical Care Medicine. 2017
- Dissociation Between Airway And Circulating Autoantibodies Levels In Stable COPD Patients. American Journal of Respiratory and Critical Care Medicine. 2017
- Prostaglandin E2 Attenuates Cigarette Smoke-Induced Cellular Inflammation In A Socs3-Independent Manner. American Journal of Respiratory and Critical Care Medicine. 2017
- Sputum But Not Circulating Autoantibodies Associated With Exacerbations Risk In Patients With Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 2017
- Compromised Nasal Host Response Contributes To Invasive Pneumococcal Disease In Cigarette Smoke-Exposed Mice. American Journal of Respiratory and Critical Care Medicine. 2016
- Detrimental Role Of Il-1 beta In A Mouse Model Of Cigarette Smoke And H1n1 Influenza Infection. American Journal of Respiratory and Critical Care Medicine. 2016
- The Effects Of Chronic Cigarette Smoke Exposure On Cardiovascular Function In Mice. American Journal of Respiratory and Critical Care Medicine. 2016
- Total Particulate Matter Concentration Skews The Gene Expression Pattern In Cigarette Smoke-Exposed Mice Towards An Inflammatory Phenotype: A Gene-Expression Study. American Journal of Respiratory and Critical Care Medicine. 2016
- Crucial Role Of Baff And B Cell/macrophage Interaction In The Autoimmune-Like Response Induced By Chronic Exposure To Cigarette Smoke. American Journal of Respiratory and Critical Care Medicine. 2015
- Il-17a Is Increased In Advanced COPD And During AeCOPD. American Journal of Respiratory and Critical Care Medicine. 2015
- Modelling Viral Exacerbations Of Chronic Obstructive Pulmonary Disease: The Heart Of The Problem. American Journal of Respiratory and Critical Care Medicine. 2015
- Cigarette Smoke Exposure Increases Invasive Pneumococcal Disease In A Mouse Model Of Nasal Bacterial Colonization. American Journal of Respiratory and Critical Care Medicine. 2014
- Il-17a Is Critical For Non-Typable Haemophilus Influenzae Exacerbation Of Cigarette Smoke-Induced Inflammation. American Journal of Respiratory and Critical Care Medicine. 2014
- Comparison Of The Genes, Pathways And Biological Functions Affected By Cigarette Smoke Exposure Between Mice And Humans. American Journal of Respiratory and Critical Care Medicine. 2013
- Fkbp13 Deficiency Leads To An Exacerbated Inflammatory Response And Increased Lung Compliance Following Cigarette Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2013
- Precision Cut Lung Slices: A Novel Method For Examining Mechanisms Underlying Complex Respiratory Diseases. American Journal of Respiratory and Critical Care Medicine. 2013
- Therapeutic Interventions Using "peroxisome Proliferator-Activated Receptor" (ppar) Gamma And "liver X Receptor" (lxr) Agonists Reduce Cigarette Smoke-Induced Inflammation And Restore Host Defense Against Bacterial Exacerbations In Mice. American Journal of Respiratory and Critical Care Medicine. 2013
- Dysregulation of mitochondrial dynamics and activation of the autophagy cascade occur in a mouse model of cigarette smoke-induced ovarian follicle loss. Fertility and Sterility. S222-S222. 2012
- Cigarette smoke-induced inflammation and respiratory host defense: Insights from animal models. Pulmonary Pharmacology and Therapeutics. 257-262. 2012
- Altered Skeletal Muscle Homeostasis In A Pre-Clinical Model Of Cigarette Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2011
- Cigarette Smoke Alters Alveolar Macrophage Cytokine Responses To Bacteria In A Murine Model. American Journal of Respiratory and Critical Care Medicine. 2011
- Induction Of Anti-Nuclear Autoantibodies And Influence Of Autoimmune Prone Phenotype On The Resolution Of Cigarette Smoke-Induced Lung Inflammation In A Pre-Clinical Model Of Cigarette Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2011
- Targeting Peroxisome Proliferator Activated Receptor-Gamma May Be Important For Attenuating Exacerbated Inflammatory Responses To Influenza A Virus In Smoke-Exposed Mice. American Journal of Respiratory and Critical Care Medicine. 2010
- Treating Viral Exacerbations Of COPD With Steroids: Lessons Learned From Animal Models Of Cigarette Smoke Exposure And Influenza A Virus Infection. American Journal of Respiratory and Critical Care Medicine. 2010
- BRP-39 But Not AMCase Is Increased In Murine Models Of Cigarette Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2010
- Cigarette Smoke Attenuates House Dust Mite Induced Allergic Airway Inflammation In Mice. American Journal of Respiratory and Critical Care Medicine. 2010
- Role Of IL-1 In Cigarette Smoke-Induced Acute Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 2010
- GM-CSF Overexpression in the Lung Changes Immune Susceptibility and Responsiveness to House Dust Mite Exposure.. American Journal of Respiratory and Critical Care Medicine. 2009
- Chemokine Dysregulation in Heterologous Viral-Bacterial Infection.. American Journal of Respiratory and Critical Care Medicine. 2009
- Cigarette Smoke Exposure Increases Mast Cells and mMCP-1 in the Murine Lung.. American Journal of Respiratory and Critical Care Medicine. 2009
- Lung-Epithelial Conditional Knockout of C/EBP beta Impairs the Response to Tobacco Smoke and Respiratory Pathogens.. American Journal of Respiratory and Critical Care Medicine. 2009
- Non-Invasive Assessment of Lung Status by CT and Ventilation/Perfusion SPECT Imaging in a Mouse Model of Smoke Exposure. American Journal of Respiratory and Critical Care Medicine. 2009
- Expression of GM-CSF in the airway drives Th2 differentiation and effector function in mice exposed to ragweed intranasally. Journal of Allergy and Clinical Immunology. S296-S297. 2002
- IL-10 inhibits allergen-specific TH2 cytokine production by human peripheral blood mononuclear cells from patients with ragweed allergies. Journal of Allergy and Clinical Immunology. S66-S66. 2002
- Cloning of Human Anti-lgE Autoantibodies and Their Role in the Regulation of IgE Synthesis. International Archives of Allergy and Immunology. 48-50. 1995
- Neuroendocrine and autoimmune regulation of the allergic response.. Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt f�r Sera und Impfstoffe) Langen. 293-299. 1994
- ANTI-IGE AUTOANTIBODIES - A FUNCTIONAL COMPARISON WITH HETEROLOGOUS ANTIBODIES. PROGRESS IN ALLERGY AND CLINICAL IMMUNOLOGY, VOL 2, KYOTO. 611-614. 1992
- IGE AND ANTI-IGE ANTIBODIES - KEY ELEMENTS IN THE ALLERGIC RESPONSE. HIGHLIGHTS IN ALLERGY AND CLINICAL IMMUNOLOGY. 35-38. 1992
- IMMUNOREGULATION BY ANTI-IMMUNOGLOBULIN-E AUTOANTIBODIES. ADVANCES IN ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 3-8. 1992
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journal articles
- Cannabis smoke suppresses antiviral immune responses to influenza A in mice. ERJ Open Research. 9:00219-2023. 2023
- Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions. Nature Microbiology. 7:1361-1375. 2022
- Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar–capillary barrier function during influenza infection. European Respiratory Journal. 60:2102049-2102049. 2022
- Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease. Microbiology spectrum. 10:e0259321. 2022
- Detecting immunoglobulins in processed sputa. Acta Allergologica. 76:3798-3800. 2021
- Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract. Mucosal Immunology. 14:1067-1076. 2021
- Development and validation of a mouse model of contemporary cannabis smoke exposure. ERJ Open Research. 7:00107-2021. 2021
- Differential expression of sputum and serum autoantibodies in patients with chronic obstructive pulmonary disease. American Journal of Physiology - Lung Cellular and Molecular Physiology. 320:L1169-L1182. 2021
- Current smoking status is associated with reduced sputum immunoglobulin M and G expression in COPD. European Respiratory Journal. 57:1902338-1902338. 2021
- Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling. Frontiers in Immunology. 12:740330. 2021
- Multi-omic meta-analysis identifies functional signatures of airway microbiome in chronic obstructive pulmonary disease. The ISME Journal. 14:2748-2765. 2020
- Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice. European Respiratory Journal. 56:2000404-2000404. 2020
- Dissociation between airway and systemic autoantibody responses in chronic obstructive pulmonary disease. ANNALS OF TRANSLATIONAL MEDICINE. 8:918-918. 2020
- Performance Characteristics of Spirometry With Negative Bronchodilator Response and Methacholine Challenge Testing and Implications for Asthma Diagnosis. Chest. 158:479-490. 2020
- A Refined View of Airway Microbiome in Chronic Obstructive Pulmonary Disease at Species and Strain-Levels. Frontiers in Microbiology. 11:1758. 2020
- Disruption of Physiological Rhythms Persist Following Cessation of Cigarette Smoke Exposure in Mice. Frontiers in Physiology. 11:501383. 2020
- Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke. ERJ Open Research. 6:00265-2019. 2020
- Transcriptomic and barrier responses of human airway epithelial cells exposed to cannabis smoke. Physiological Reports. 7:e14249. 2019
- Statins Promote Interleukin-1β–Dependent Adipocyte Insulin Resistance Through Lower Prenylation, Not Cholesterol. Diabetes. 68:1441-1448. 2019
- c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells. Cell Reports. 27:2304-2312.e6. 2019
- The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells. Scientific Reports. 9:153. 2019
- A comparative analysis of cannabis and tobacco smoke exposure on human airway epithelial cell gene expression, immune phenotype, and response to formoterol and budesonide treatment 2019
- Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease. American Journal of Respiratory and Critical Care Medicine. 198:850-858. 2018
- The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD. Scientific Reports. 8:11881. 2018
- Does Compromised Immune Exclusion Drive Inflammatory Processes in Chronic Obstructive Pulmonary Disease?. American Journal of Respiratory Cell and Molecular Biology. 58:671-672. 2018
- Identification of Drug Candidates to Suppress Cigarette Smoke–induced Inflammation via Connectivity Map Analyses. American Journal of Respiratory Cell and Molecular Biology. 58:727-735. 2018
- The immune system as a victim and aggressor in chronic obstructive pulmonary disease. Journal of Thoracic Disease. 10:S2011-S2017. 2018
- Identification of microRNAs as potential markers of ovarian toxicity. Journal of Applied Toxicology. 38:744-752. 2018
- Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF. Respiratory Research. 18:48. 2017
- Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination. Journal of Virology. 91:e01234-e01217. 2017
- Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice. Infection and Immunity. 85:e00434-e00417. 2017
- Targeting Interleukin-17 signalling in cigarette smoke-induced lung disease: Mechanistic concepts and therapeutic opportunities. Pharmacology and Therapeutics. 178:123-131. 2017
- Increased IL-17RA and IL-17RC in End-Stage COPD and the Contribution to Mast Cell Secretion of FGF-2 and VEGF. Respiratory Research. 18. 2017
- Induction of pulmonary antibodies against oxidized lipids in mice exposed to cigarette smoke. Respiratory Research. 17:97. 2016
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Role of
BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice. Physiological Reports. 4:e13057. 2016 - Total particulate matter concentration skews cigarette smoke's gene expression profile. ERJ Open Research. 2:00029-2016. 2016
- Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway. PLoS Pathogens. 12:e1005706-e1005706. 2016
- Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary. Reproductive Toxicology. 61:105-113. 2016
- Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice. Infection and Immunity. 84:1536-1547. 2016
- Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway. PLoS Pathogens. 12:e1005589-e1005589. 2016
- Small airway epithelial-C/EBPβ is increased in patients with advanced COPD. Respiratory Research. 16:133. 2015
- Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice. European Respiratory Journal. 46:1451-1460. 2015
- Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice1. Biology of Reproduction. 93:93. 2015
- IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 192:428-437. 2015
- IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis. American Journal of Respiratory and Critical Care Medicine. 191:1232-1241. 2015
- IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke–induced Lymphoid Neogenesis. American Journal of Respiratory and Critical Care Medicine. 191:1232-1241. 2015
- Impacts of peroxisome proliferator-activated receptor-γ activation on cigarette smoke-induced exacerbated response to bacteria. European Respiratory Journal. 45:191-200. 2015
- Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction. Respiratory Research. 15:42. 2014
- Influenza Promotes Collagen Deposition via αvβ6 Integrin-mediated Transforming Growth Factor β Activation. Journal of Biological Chemistry. 289:35246-35263. 2014
- Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure. Respiratory Research. 15:49. 2014
- Cigarette Smoke Primes the Pulmonary Environment to IL-1α/CXCR-2–Dependent Nontypeable Haemophilus influenzae–Exacerbated Neutrophilia in Mice. Journal of Immunology. 193:3134-3145. 2014
- A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure. PLoS ONE. 9:e88714-e88714. 2014
- Impact of Cigarette Smoke on the Human and Mouse Lungs: A Gene-Expression Comparison Study. PLoS ONE. 9:e92498-e92498. 2014
- Detection of Lung Dysfunction Using Ventilation and Perfusion SPECT in a Mouse Model of Chronic Cigarette Smoke Exposure. Journal of Nuclear Medicine. 54:616-623. 2013
- IL-1 Receptor Regulates microRNA-135b Expression in a Negative Feedback Mechanism during Cigarette Smoke–Induced Inflammation. Journal of Immunology. 190:3679-3686. 2013
- Asthma Associated With Incontinentia Pigmenti and Fanconi Anemia. Chest. 143:856-858. 2013
- Cigarette Smoke Exposure Elicits Increased Autophagy and Dysregulation of Mitochondrial Dynamics in Murine Granulosa Cells1. Biology of Reproduction. 88:63. 2013
- Alterations in Skeletal Muscle Cell Homeostasis in a Mouse Model of Cigarette Smoke Exposure. PLoS ONE. 8:e66433-e66433. 2013
- Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis. PLoS ONE. 8:e59185-e59185. 2013
- The Influence of Cigarette Smoking on Viral Infections. Chest. 143:196-206. 2013
- Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice. Respiratory Research. 13:81. 2012
- Cigarette smoke and platelet-activating factor receptor dependent adhesion ofStreptococcus pneumoniaeto lower airway cells. Thorax. 67:908-913. 2012
- Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection: Genomic Insights. Journal of Immunology. 188:832-843. 2012
- Cigarette Smoke Exposure Leads to Follicle Loss via an Alternative Ovarian Cell Death Pathway in a Mouse Model. Toxicological Sciences. 125:274-284. 2012
- Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation. Respiratory Research. 12:39. 2011
- Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood. Mucosal Immunology. 4:682-694. 2011
- Cigarette Smoke Differentially Affects Eosinophilia and Remodeling in a Model of House Dust Mite Asthma. American Journal of Respiratory Cell and Molecular Biology. 45:753-760. 2011
- Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice. American Journal of Physiology - Lung Cellular and Molecular Physiology. 301:L391-L401. 2011
- A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke. European Respiratory Journal. 38:285-294. 2011
- Lung Epithelial CCAAT/Enhancer-binding Protein-β Is Necessary for the Integrity of Inflammatory Responses to Cigarette Smoke. American Journal of Respiratory and Critical Care Medicine. 184:233-242. 2011
- IL-1α/IL-1R1 Expression in Chronic Obstructive Pulmonary Disease and Mechanistic Relevance to Smoke-Induced Neutrophilia in Mice. PLoS ONE. 6:e28457-e28457. 2011
- Mechanisms of clearance of nontypeable Haemophilus influenzae from cigarette smoke-exposed mouse lungs. European Respiratory Journal. 36:1131-1142. 2010
- Treating Viral Exacerbations of Chronic Obstructive Pulmonary Disease: Insights from a Mouse Model of Cigarette Smoke and H1N1 Influenza Infection. PLoS ONE. 5:e13251-e13251. 2010
- The role of the CCR1 receptor in the inflammatory response to tobacco smoke in a mouse model. Inflammation Research. 59:817-825. 2010
- Innate Immune Processes Are Sufficient for Driving Cigarette Smoke–Induced Inflammation in Mice. American Journal of Respiratory Cell and Molecular Biology. 42:394-403. 2010
- Dysregulated Macrophage-Inflammatory Protein-2 Expression Drives Illness in Bacterial Superinfection of Influenza. Journal of Immunology. 184:2001-2013. 2010
- Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke. BMC Medical Genetics. 2:56. 2009
- Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1. Experimental Cell Research. 315:3486-3499. 2009
- Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs. Molecular Immunology. 46:3108-3116. 2009
- Cigarette smoke causes follicle loss in mice ovaries at concentrations representative of human exposure. Human Reproduction. 24:1452-1459. 2009
- How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nature Reviews Immunology. 9:377-384. 2009
- Bacteria Challenge in Smoke-exposed Mice Exacerbates Inflammation and Skews the Inflammatory Profile. American Journal of Respiratory and Critical Care Medicine. 179:666-675. 2009
- Acute, but Not Resolved, Influenza A Infection Enhances Susceptibility to House Dust Mite-Induced Allergic Disease. Journal of Immunology. 182:3095-3104. 2009
- Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-β production. Molecular Immunology. 46:821-829. 2009
- Adjuvant and Anti-Inflammatory Properties of Cigarette Smoke in Murine Allergic Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. 40:38-46. 2009
- Toxicogenomic Analysis of Mainstream Tobacco Smoke-Exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart. Inhalation Toxicology. 21:78-85. 2009
- Cigarette Smoke Suppresses Type I Interferon-Mediated Antiviral Immunity in Lung Fibroblast and Epithelial Cells. Journal of Interferon and Cytokine Research. 28:167-179. 2008
- Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. Journal of Leukocyte Biology. 83:774-784. 2008
- Cigarette Smoke Exposure Attenuates Cytokine Production by Mouse Alveolar Macrophages. American Journal of Respiratory Cell and Molecular Biology. 38:218-226. 2008
- Impact of cigarette smoke on T and B cell responsiveness. Cellular Immunology. 253:38-44. 2008
- Kinetics of in vitro bronchoconstriction in an elastolytic mouse model of emphysema. European Respiratory Journal. 30:691-700. 2007
- Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection. Journal of Immunology. 179:4015-4026. 2007
- Critical negative regulation of immunopathology by signaling intracellular infection. Journal of Immunology. 179:4015-4026. 2007
- Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. American Journal of Physiology - Lung Cellular and Molecular Physiology. 293:L730-L739. 2007
- Eosinophilia is induced in the colon of Th2-sensitized mice upon exposure to locally expressed antigen. American Journal of Physiology - Gastrointestinal and Liver Physiology. 293:G383-G390. 2007
- Mainstream Tobacco Smoke Causes Paternal Germ-Line DNA Mutation. Cancer Research. 67:5103-5106. 2007
- Cigarette Smoke Impairs NK Cell-Dependent Tumor Immune Surveillance. Journal of Immunology. 178:936-943. 2007
- Animal Models of Chronic Obstructive Pulmonary Disease Exacerbations. Contributions to microbiology. 14:126-141. 2007
- Cigarette Smoke Impacts Immune Inflammatory Responses to Influenza in Mice. American Journal of Respiratory and Critical Care Medicine. 174:1342-1351. 2006
- Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues. Journal of Immunology. 176:2568-2580. 2006
- Prolonged Ovalbumin Exposure Attenuates Airway Hyperresponsiveness and T Cell Function in Mice. International Archives of Allergy and Immunology. 141:130-140. 2006
- Mainstream Cigarette Smoke Exposure Attenuates Airway Immune Inflammatory Responses to Surrogate and Common Environmental Allergens in Mice, Despite Evidence of Increased Systemic Sensitization. Journal of Immunology. 175:2834-2842. 2005
- B7RP-1 Is Not Required for the Generation of Th2 Responses in a Model of Allergic Airway Inflammation but Is Essential for the Induction of Inhalation Tolerance. Journal of Immunology. 174:3000-3005. 2005
- Cutaneous Antigen Priming via Gene Gun Leads to Skin-Selective Th2 Immune-Inflammatory Responses. Journal of Immunology. 174:1664-1674. 2005
- Impact of Cigarette Smoke on Clearance and Inflammation after Pseudomonas aeruginosa Infection. American Journal of Respiratory and Critical Care Medicine. 170:1164-1171. 2004
- The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigenin vivo. Clinical and Experimental Immunology. 138:213-220. 2004
- Concomitant airway expression of granulocyte‐macrophage colony‐stimulating factor and decorin, a natural inhibitor of transforming growth factor‐β, breaks established inhalation tolerance. European Journal of Immunology. 34:2375-2386. 2004
- Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis. Journal of Immunology. 173:2099-2108. 2004
- Cigarette Smoke Decreases Pulmonary Dendritic Cells and Impacts Antiviral Immune Responsiveness. American Journal of Respiratory Cell and Molecular Biology. 30:202-211. 2004
- Interleukin-13–Dependent Expression of Matrix Metalloproteinase-12 Is Required for the Development of Airway Eosinophilia in Mice. American Journal of Respiratory Cell and Molecular Biology. 30:84-90. 2004
- Chronic Exposure to Innocuous Antigen in Sensitized Mice Leads to Suppressed Airway Eosinophilia That Is Reversed by Granulocyte Macrophage Colony-Stimulating Factor. Journal of Immunology. 169:3499-3506. 2002
- Chronic exposure to innocuous leads to suppressed airway antigen in sensitized mice eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. Journal of Immunology. 169:3499-3506. 2002
- Granulocyte Macrophage Colony–Stimulating Factor–Driven Respiratory Mucosal Sensitization Induces Th2 Differentiation and Function Independently of Interleukin-4. American Journal of Respiratory Cell and Molecular Biology. 27:428-435. 2002
- On the generation of allergic airway diseases: from GM-CSF to Kyoto. Trends in Immunology. 23:396-402. 2002
- Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clinical and Experimental Allergy. 32:411-421. 2002
- Compartmentalized transgene expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in mouse lung enhances allergic airways inflammation. Clinical and Experimental Immunology. 113:157-165. 2001
- Temporal–Spatial Analysis of the Immune Response in a Murine Model of Ovalbumin-Induced Airways Inflammation. American Journal of Respiratory Cell and Molecular Biology. 25:326-334. 2001
- Generation of experimental allergic airways inflammation in the absence of draining lymph nodes. Journal of Clinical Investigation. 108:577-583. 2001
- Expression of the Th1 Chemokine IFN-γ-Inducible Protein 10 in the Airway Alters Mucosal Allergic Sensitization in Mice. Journal of Immunology. 166:2750-2759. 2001
- Determinants of the immune-inflammatory response in allergic airway inflammation: Overview of antigen presentation and cellular activation. Journal of Allergy and Clinical Immunology. 106:S206-S212. 2000
- Transient Transgenic Approaches for Investigating the Role of Granulocyte- Macrophage Colony-Stimulating Factor in Pulmonary Inflammatory and Immune Diseases. Methods in Molecular Medicine. 44:161-178. 2000
- Interleukin-10 Gene Transfer to the Airway Regulates Allergic Mucosal Sensitization in Mice. American Journal of Respiratory Cell and Molecular Biology. 21:586-596. 1999
- Regulation of Allergic Mucosal Sensitization by Interleukin-12 Gene Transfer to the Airway. American Journal of Respiratory Cell and Molecular Biology. 21:317-326. 1999
- Interaction of Human IgE with Fc Epsilon RI Alpha Exposes Hidden Epitopes on IgE. International Archives of Allergy and Immunology. 120:295-302. 1999
- Adenoviral infection inhibits allergic airways inflammation in mice. Clinical and Experimental Allergy. 28:1581-1590. 1998
- GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.. Journal of Clinical Investigation. 102:1704-1714. 1998
- Disruption of antigen-induced inflammatory responses in CD40 ligand knockout mice.. Journal of Clinical Investigation. 101:1342-1353. 1998
- Antigen Interaction and Heat Inactivation Expose New Epitopes on Human IgE. International Archives of Allergy and Immunology. 117:231-238. 1998
- Eosinophilia in antigen-induced airways inflammation.. Canadian Respiratory Journal. 5 Suppl A:31A-35A. 1998
- Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation.. American Journal of Respiratory Cell and Molecular Biology. 16:510-520. 1997
- Neuropeptides accentuate interleukin‐4 induced human immunoglobuline E synthesis in vitro. Experimental Dermatology. 5:38-44. 1996
- Natural And Recombinant ANTI-IgE Autoantibodies. Advances in Experimental Medicine and Biology. 409:411-416. 1996
- Antigen-specific inhibition of IgE binding to the high-affinity receptor.. Journal of Immunology. 155:2948-2954. 1995
- Inhibition of human IgE synthesis by anti‐IgE antibodies requires divalent recognition. European Journal of Immunology. 24:2161-2167. 1994
- Neuropeptides are potent modulators of human in vitro immunoglobulin E synthesis. European Journal of Immunology. 24:1908-1913. 1994
- Domain-Specific Anti-IgE Antibodies Interfere with IgE Binding to FcεRII. International Archives of Allergy and Immunology. 105:75-82. 1994
- A Specific Feedback by Anti-IgE Autoantibodies on the Cytokine Network in Allergy. Agents and Actions Supplements. 40:144-152. 1993
- Biological Activities of Anti-IgE Antibodies. International Archives of Allergy and Immunology. 102:121-126. 1993