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Inflammatory Endotype-Associated Airway Resistome...
Journal article

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease

Abstract

Antimicrobial resistance is a global concern in chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). The collection of antibiotic resistance genes or resistome in human airways may underlie the resistance. COPD is heterogeneous, and understanding the airway resistome in relation to patient phenotype and endotype may inform precision antibiotic therapy. Here, we characterized the airway resistome for 94 COPD …

Authors

Yi X; Li Y; Liu H; Liu X; Yang J; Gao J; Yang Y; Liang Z; Wang F; Chen D

Journal

Microbiology Spectrum, Vol. 10, No. 2, pp. e02593–e02521

Publisher

American Society for Microbiology

Publication Date

April 27, 2022

DOI

10.1128/spectrum.02593-21

ISSN

2165-0497