Journal article
The role of the CCR1 receptor in the inflammatory response to tobacco smoke in a mouse model
Abstract
ObjectiveThe aim was to create pathological changes in mice relevant to human smoke exposure that can be used to further understand the mechanisms and pathology of smoke-induced inflammatory disease.MethodsMice were exposed to tobacco smoke or lipopolysaccharide (LPS) to generate an inflammatory infiltrate within the lungs.ResultsTobacco smoke exposure over a 4 day period led to neutrophilia in the lungs of BALB/c mice. Within the inflammatory …
Authors
Önnervik P-O; Lindahl M; Svitacheva N; Stämpfli M; Thim K; Smailagic A; Virtala R; Taylor JD
Journal
Inflammation Research, Vol. 59, No. 10, pp. 817–825
Publisher
Springer Nature
Publication Date
10 2010
DOI
10.1007/s00011-010-0193-5
ISSN
1023-3830