BMJ Open Journal

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Overview

publication venue for

• EFFECTIVENESS OF IMPLEMENTATION INTERVENTIONS IN IMPROVING PHYSICIAN ADHERENCE TO GUIDELINE RECOMMENDATIONS IN HEART FAILURE: A SYSTEMATIC REVIEW 2017
• Scoping review exploring the impact of hip fracture in older adults with cognitive impairment or dementia..  15:e093893. 2025
• Exploring the feasibility of using discrete choice experiment (DCE) to elicit preferences among children and adolescents: protocol for a convergent parallel mixed methods study..  15:e097598. 2025
• Implementing physical activity for individuals with cancer during treatment: protocol for the IMPACT implementation-effectiveness trial..  15:e101013. 2025
• Changing primary care capacity in Canada: protocol for a cross-provincial mixed methods study..  15:e099302. 2025
• Cost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia..  15:e087333. 2025
• The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study..  15:e100568. 2025
• Examining experiences and system impacts of publicly funded episodic virtual care: protocol for a cross-provincial mixed methods study..  15:e099098. 2025
• Prospective harmonisation of four international randomised controlled trials in Canada, China, India and South Africa: the Healthy Life Trajectories Initiative..  15:e086233. 2025
• Narrative enhancement and cognitive therapy for self-stigma among youth with bipolar disorder or multiple mental health conditions: protocol for a pilot randomised basket trial..  15:e096222. 2025
• Clinicians' experience with infographic summaries from the BMJ Rapid Recommendations: a qualitative user-testing study among residents and interns at a large teaching hospital in Switzerland..  15:e083032. 2025
• Establishing primary care physician commitment in Canadian long-term care homes: a protocol for a modified e-Delphi study..  15:e093277. 2025
• Interventions for the management of post-COVID-19 condition (long COVID): protocol for a living systematic review and network meta-analysis..  15:e086407. 2025
• High-intensive physical rehabilitation approach in children and adolescents with acquired brain injury during subacute phase (REHABILITY): a feasibility study protocol..  15:e087768. 2025
• Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort study..  15:e086932. 2025
• Patient preferences for drug therapy in inflammatory arthritis: protocol for a living systematic review and evidence map to inform clinical practice guidelines..  15:e088267. 2025
• Development of a predictive model for loss of functional and cognitive abilities in long-term care home residents: a protocol..  15:e086935. 2025
• Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial..  15:e087704. 2025
• Effects of nurse-home visiting on intimate partner violence and maternal income, mental health and self-efficacy by 24 months postpartum: a randomised controlled trial (British Columbia Healthy Connections Project)..  15:e083147. 2025
• Exploring the landscape of Canadian midwifery research: strengths, gaps and priorities - results of a scoping review..  14:e087698. 2024
• Promoting Intensive Transitions for Children and Youth with Medical Complexity from Paediatric to Adult Care: the PITCare study-protocol for a randomised controlled trial..  14:e086088. 2024
• Supporting resident-centred decision-making about transitions from long-term care homes to hospital: a qualitative study protocol..  14:e086748. 2024
• Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)..  14:e084825. 2024
• Mapping context of sedentary behaviour in older adults who are prefrail and frail: an analysis of secondary outcomes from a longitudinal study (MAPS-B)..  14:e084610. 2024
• Physical activity promotion intervention improved physical activity knowledge, confidence and behaviour among diverse immigrant women: pre-post multiple methods feasibility study..  14:e086653. 2024
• Tushirikiane-4-Uthabiti (Supporting Each Other For Resilience): study protocol of a mental health, HIV self-testing and livelihoods randomised controlled trial for advancing HIV prevention outcomes among urban refugee youth in Kampala, Uganda..  14:e087470. 2024
• Economic effects of priority setting in healthcare: a scoping review of current evidence..  14:e086342. 2024
• Multicentre randomised controlled trial comparing Bankart repair with remplissage and Latarjet procedure in shoulder instability with subcritical bone loss (STABLE): study protocol..  14:e089831. 2024
• Methodological standards in the design and reporting of pilot and feasibility studies in emergency medicine literature: a systematic review..  14:e082648. 2024
• Nepal Family Cohort study: a study protocol..  14:e088896. 2024
• Perspectives on the sustained engagement with digital health tools: protocol for a qualitative interview study among people living with Inflammatory Bowel Disease or irritable bowel syndrome..  14:e089220. 2024
• Experiences of physiotherapists working with adults living with Long COVID in Canada: a qualitative study..  14:e086357. 2024
• STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) before surgery..  14:e093710. 2024
• Traditional, complementary and integrative medicine therapies for the treatment of mild/moderate acute COVID-19: protocol for a systematic review and network meta-analysis..  14:e088959. 2024
• The efficacy of valproate in acute mania, bipolar depression and maintenance therapy for bipolar disorder: an overview of systematic reviews with meta-analyses..  14:e087999. 2024
• Quality and completeness of, and spin in reporting of, pilot and feasibility studies in hip and knee arthroplasty: a protocol for a methodological survey..  14:e085441. 2024
• Implementation of an electronic prospective surveillance model for cancer rehabilitation: a mixed methods study protocol..  14:e090449. 2024
• Road to Recovery: protocol for a mixed-methods prospective cohort study evaluating the impact of a new model of substance use care in a Canadian setting..  14:e090608. 2024
• Systematic scoping review of cluster randomised trials conducted exclusively in low-income and middle-income countries between 2017 and 2022..  14:e087724. 2024
• Fatherhood and men's participation in antenatal care in rural sub-Saharan Africa: a scoping review protocol..  14:e085901. 2024
• Supported decision-making with persons with dementia: a scoping review protocol in partnership with lived experts.  14:e085954-e085954. 2024
• Disparity between statistical and clinical significance in published randomised controlled trials indexed in PubMed: a protocol for a cross-sectional methodological survey.  14:e084375-e084375. 2024
• Selective early medical treatment of the patent ductus arteriosus in extremely low gestational age infants: a pilot randomised controlled trial protocol (SMART-PDA).  14:e087998-e087998. 2024
• Calcineurin Inhibitor in NEuRoloGically deceased donors to decrease kidney delayed graft function study: study protocol of the CINERGY Pilot randomised controlled trial.  14:e086777-e086777. 2024
• Chronic obstructive pulmonary disease exacerbation purulence status and its association with pulmonary embolism: protocol for a systematic review with meta-analysis.  14:e085328-e085328. 2024
• PRECISE trial (Pain RElief Combination Intervention StratEgies): protocol for the clinical trial of a pregabalin–melatonin combination for fibromyalgia.  14:e087180-e087180. 2024
• Protocol for Improving Care by FAster risk-STratification through use of high sensitivity point-of-care troponin in patients presenting with possible acute coronary syndrome in the EmeRgency department (ICare-FASTER): a stepped-wedge cluster randomised quality improvement initiative.  14:e083752-e083752. 2024
• Coordination of oral anticoagulant care at hospital discharge (COACHeD): pilot randomised controlled trial.  14:e079353-e079353. 2024
• Describing primary care patterns before and during the COVID-19 pandemic across Canada: a quasi-experimental pre–post design cohort study using national practice-based research network data.  14:e084608-e084608. 2024
• Impact of social determinants of health on progression from potentially life-threatening complications to near miss events and death during pregnancy and post partum in a middle-income setting: an observational study.  14:e081996-e081996. 2024
• Patient, caregiver and other knowledge user engagement in consensus-building healthcare initiatives: a scoping review protocol.  14:e080822-e080822. 2024
• Protocol for the development of the Chatbot Assessment Reporting Tool (CHART) for clinical advice.  14:e081155-e081155. 2024
• Sex and gender-based analysis and diversity metric reporting in acute care trials published in high-impact journals: a systematic review.  14:e081118-e081118. 2024
• ‘It’s just my knee’: a qualitative study investigating the process of reframing and young athletes’ perceived quality of life between anterior cruciate ligament injury and surgery.  14:e076799-e076799. 2024
• Evidence related to a vegetarian diet and metabolic dysfunction-associated steatotic liver disease: protocol for a scoping review.  14:e079750-e079750. 2024
• Global trends in chronic kidney disease-related mortality: a systematic review protocol.  14:e078485-e078485. 2024
• REporting quality of PilOt randomised controlled trials in surgery (REPORTS): a methodological survey protocol.  14:e085293-e085293. 2024
• The Pediatric Autism Research Cohort (PARC) Study: protocol for a patient-oriented prospective study examining trajectories of functioning in children with autism.  14:e083045-e083045. 2024
• Co-creating a new Charter for equitable and inclusive co-creation: insights from an international forum of academic and lived experience experts.  14:e078950-e078950. 2024
• Developing a reporting item checklist for studies of HIV drug resistance prevalence or incidence: a mixed methods study.  14:e080014-e080014. 2024
• Effectiveness of metformin to pregnant women with PCOS to reduce spontaneous abortion and gestational diabetes mellitus: a protocol for an overview of reviews.  14:e078217-e078217. 2024
• Investigation of divergent thinking among surgeons and surgeon trainees in Canada (IDEAS): a mixed-methods study.  14:e081367-e081367. 2024
• Prepregnancy body mass index and other risk factors for early-onset and late-onset haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome: a population-based retrospective cohort study in British Columbia, Canada.  14:e079131-e079131. 2024
• Effects of ambient air pollution on obesity and ectopic fat deposition: a protocol for a systematic review and meta-analysis.  14:e080026-e080026. 2024
• Sepsis policy, guidelines and standards in Canada: a jurisdictional scoping review protocol.  14:e077909-e077909. 2024
• Understanding the use and outcomes of high-flow nasal cannula among infants admitted to Canadian hospitals with bronchiolitis (CanFLO): a protocol for a multicentre, retrospective cohort study.  14:e080197-e080197. 2024
• Cannabis for medical use versus opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised clinical trials.  14:e068182-e068182. 2024
• International consensus statement on the design, delivery and evaluation of sport-based interventions aimed at promoting social, psychological and physical well-being in prison.  14:e075792-e075792. 2024
• Development of indicators for avoidable emergency medical service calls by mapping paramedic clinical impression codes to ambulatory care sensitive conditions and mental health conditions in the UK and Canada.  13:e073520-e073520. 2023
• Understanding and addressing changing administrative workload in primary care in Canada: protocol for a mixed-method study.  13:e076917-e076917. 2023
• What is the optimal assessment of speech? A multicentre, international evaluation of speech assessment in 2500 patients with a cleft.  13:e071571-e071571. 2023
• Burden, determinants, consequences and care of multimorbidity in rural and urbanising Telangana, India: protocol for a mixed-methods study within the APCAPS cohort.  13:e073897-e073897. 2023
• Cost-effectiveness analysis of the Geriatric Fracture Center (GFC) concept: a prospective multicentre cohort study.  13:e072744-e072744. 2023
• Delphi consensus study to develop guidelines for the management of adults with borderline personality disorder in the emergency department: a protocol.  13:e075119-e075119. 2023
• Exploring the outcomes of research engagement using the observation method in an online setting.  13:e073953-e073953. 2023
• How do network meta-analyses address intransitivity when assessing certainty of evidence: a systematic survey.  13:e075212-e075212. 2023
• Infographic summaries for clinical practice guidelines: results from user testing of the BMJ Rapid Recommendations in primary care.  13:e071847-e071847. 2023
• Intranasal antihistamines and corticosteroids in the treatment of allergic rhinitis: a systematic review and meta-analysis protocol.  13:e076614-e076614. 2023
• Perceived value and benefits of the Community Paramedicine at Clinic (CP@clinic) programme: a descriptive qualitative study.  13:e076066-e076066. 2023
• Protocol for a longitudinal cohort study of Lyme disease with physical, mental and immunological assessment.  13:e076833-e076833. 2023
• Protocol for validating an algorithm to identify neurocognitive disorders in Canadian Longitudinal Study on Aging participants: an observational study.  13:e073027-e073027. 2023
• REVISE:Re-Evaluating theInhibition ofStressErosions in the ICU: a randomised trial protocol.  13:e075588-e075588. 2023
• What are effective vaccine distribution approaches for equity-deserving and high-risk populations during COVID-19? Exploring best practices and recommendations in Canada: protocol for a mixed-methods multiple case codesign study.  13:e072238-e072238. 2023
• Evaluating interactive weekly mobile phone text messaging plus motivational interviewing for breastfeeding promotion among women living with HIV, giving normal birth at a primary healthcare facility in South Africa: a feasibility randomised controlled trial.  13:e073385-e073385. 2023
• Evaluation of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) programme: a protocol of a cluster randomised control trial.  13:e073585-e073585. 2023
• Impact of strategies to mitigate misinformation in diverse settings and populations: a protocol for a living evidence synthesis.  13:e076672-e076672. 2023
• TILE pilot trial study protocol: Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol.  13:e064715-e064715. 2023
• Safety of influenza vaccination during pregnancy: a systematic review..  13:e066182. 2023
• Development of practice-based quality indicators for the primary care of older adults: a RAND/UCLA Appropriateness Method study protocol.  13:e072232-e072232. 2023
• Estimating the cost impact of atrial fibrillation using a prospective cohort study and population-based controls.  13:e072080-e072080. 2023
• Frequency of postoperative cognitive dysfunction after non-cardiac surgery and its impact on functional outcomes: protocol for a systematic review.  13:e071732-e071732. 2023
• One-year real-world outcomes for patients undergoing transcatheter mitral valve repair: the Gulf MTEER registry (GULF Mitral Transcatheter Edge to Edge Repair).  13:e073549-e073549. 2023
• Conflict of interest and funding in health communication on social media: a systematic review.  13:e072258-e072258. 2023
• Defining the capabilities and competencies of high-performing family physicians: a mixed methods study.  13:e072266-e072266. 2023
• Depression, parenting and the COVID-19 pandemic in Canada: results from three nationally representative cross-sectional surveys.  13:e063991-e063991. 2023
• For health or for profit? Understanding how private financing and for-profit delivery operate within Canadian healthcare (4H|4P): protocol for a multimethod knowledge mobilisation research project.  13:e077783-e077783. 2023
• Patient-reported, health economic and psychosocial outcomes in patients with Friedreich ataxia (PROFA): protocol of an observational study using momentary data assessments via mobile health app.  13:e075736-e075736. 2023
• Predictors of harsh parenting practices and inter-partner conflict during the COVID-19 pandemic in Ontario, Canada: a cross-sectional analysis from the Ontario Parent Survey.  13:e066840-e066840. 2023
• Protocol for the COVID-19 Wellbeing and Stress Study: a longitudinal study of parent distress, biological stress and child biopsychosocial development during the pandemic and beyond.  13:e071926-e071926. 2023
• Doppler identified venous congestion in septic shock: protocol for an international, multi-centre prospective cohort study (Andromeda-VEXUS).  13:e074843-e074843. 2023
• Evaluating the impact of including non-randomised studies of interventions in meta-analysis of randomised controlled trials: a protocol for a meta-epidemiological study.  13:e073232-e073232. 2023
• Exploring participant attrition in a longitudinal follow-up of older adults: the Global Longitudinal Study of Osteoporosis in Women (GLOW) Hamilton cohort.  13:e066594-e066594. 2023
• Identifying priority questions regarding rapid systematic reviews’ methods: protocol for an eDelphi study.  13:e069856-e069856. 2023
• Lifestyle changes during the COVID-19 pandemic in Brazil: results from three consecutive cross-sectional web surveys.  13:e070328-e070328. 2023
• TeleRehabilitation with Aims to Improve Lower extremity recovery in community-dwelling individuals who have had a stroke: protocol for a multisite, parallel group, assessor-blinded, randomised attention-controlled trial.  13:e076723-e076723. 2023
• Critical Care Cycling to ImproveLowerExtremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients.  13:e075685-e075685. 2023
• Drug interventions for prevention of COVID-19 progression to severe disease in outpatients: a systematic review with meta-analyses and trial sequential analyses (The LIVING Project).  13:e064498-e064498. 2023
• Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis.  13:e064322-e064322. 2023
• How regional versus global thresholds for physical activity and grip strength influence physical frailty prevalence and mortality estimates in PURE: a prospective multinational cohort study of community-dwelling adults.  13:e066848-e066848. 2023
• Observed intervention effects for mortality in randomised clinical trials: a methodological study protocol.  13:e072550-e072550. 2023
• Tolerability of bedtime diuretics: a prospective cohort analysis.  13:e068188-e068188. 2023
• A culturally tailored personaliseD nutrition intErvention in South ASIan women at risk of Gestational Diabetes Mellitus (DESI-GDM): a randomised controlled trial protocol.  13:e072353-e072353. 2023
• Burden of opioid toxicity death in the fentanyl-dominant era for people who experience incarceration in Ontario, Canada, 2015–2020: a whole population retrospective cohort study.  13:e071867-e071867. 2023
• Conversion between B-type natriuretic peptide and N-terminal pro B-type natriuretic peptide in perioperative risk assessment: protocol for a prospective cohort study.  13:e068147-e068147. 2023
• Nephrologists’ perspectives on the impact of COVID-19 on caring for patients undergoing dialysis in Latin America: a qualitative study.  13:e062321-e062321. 2023
• What counts as patient-important upper gastrointestinal bleeding in the ICU? A mixed-methods study protocol of patient and family perspectives.  13:e070966-e070966. 2023
• Impact of urinary sodium excretion on the prevalence and incidence of metabolic syndrome: a population-based study..  13:e065402. 2023
• Cost-utility analysis of a multispecialty interprofessional team dementia care model in Ontario, Canada.  13:e064882-e064882. 2023
• Engaging pregnant individuals and healthcare professionals in an international mixed methods study to develop a core outcome set for studies on placenta accreta spectrum disorder (COPAS): a study protocol.  13:e060699-e060699. 2023
• Investigating divergent thinking and creative ability in surgeons (IDEAS): a survey protocol.  13:e069873-e069873. 2023
• Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdrawal of life-sustaining measures.  13:e073643-e073643. 2023
• Older adults’ experiences and perceived impacts of the Aging, Community and Health Research Unit-Community Partnership Program (ACHRU-CPP) for diabetes self-management in Canada: a qualitative descriptive study.  13:e068694-e068694. 2023
• Perceptions of COVID-19 risk, vaccine access and confidence: a qualitative description of South Asians in Canada.  13:e070433-e070433. 2023
• Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial).  13:e068363-e068363. 2023
• What is the role of primary care in the COVID-19 vaccine roll-out and the barriers and facilitators to an equitable vaccine roll-out? A rapid scoping review of nine jurisdictions.  13:e065306-e065306. 2023
• Wireless physical activity monitor use among adults living with HIV in a community-based exercise intervention study: a quantitative, longitudinal, observational study.  13:e068754-e068754. 2023
• Association of the COVID-19 pandemic on stroke admissions and treatment globally: a systematic review.  13:e062734-e062734. 2023
• Can youth-engaged research facilitate equitable access to contraception in Canada? The qualitative study protocol for the Ask Us project.  13:e070904-e070904. 2023
• Factors associated with higher quality of clinical practice guidelines and their recommendations for the pharmacological treatment of depression: a systematic review.  13:e067390-e067390. 2023
• Piloting an online telecoaching community-based exercise intervention with adults living with HIV: protocol for a mixed-methods implementation science study.  13:e067703-e067703. 2023
• Retrospective cross-sectional study examining the association between loneliness and unmet healthcare needs among middle-aged and older adults using the Canadian Longitudinal Study of Aging (CLSA).  13:e068769-e068769. 2023
• ‘It’s so simple’ Lessons from the margins: a qualitative study of patient experiences of a mobile health clinic in Hamilton, Ontario, Canada.  13:e066674-e066674. 2023
• Accuracy of efficient data methods to determine the incidence of hospital-acquired thrombosis and major bleeding in medical and surgical inpatients: a multicentre observational cohort study in four UK hospitals.  13:e069244-e069244. 2023
• Association between frailty, chronic conditions and socioeconomic status in community-dwelling older adults attending primary care: a cross-sectional study using practice-based research network data.  13:e066269-e066269. 2023
• Critical appraisal and comparison of recommendations of clinical practice guidelines for the treatment of schizophrenia in children and adolescents: a methodological survey.  13:e070332-e070332. 2023
• FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer’s lactate.  13:e067142-e067142. 2023
• Global evidence of gender equity in academic health research: a scoping review.  13:e067771-e067771. 2023
• High continuous positive airway pressures versus non-invasive positive pressure ventilation in preterm neonates: protocol for a multicentre pilot randomised controlled trial.  13:e069024-e069024. 2023
• Examining the immediate and ongoing impact of the COVID-19 pandemic on population-based estimates of dementia: a population-based time series analysis in Ontario, Canada.  13:e067689-e067689. 2023
• Mental health and well-being of unpaid caregivers: a cross-sectional survey protocol.  13:e070374-e070374. 2023
• Preferences, barriers and facilitators regarding virtual pelvic healthcare in individuals with gynaecological cancers: protocol for a patient-oriented, mixed-methods study.  13:e067606-e067606. 2023
• Protocol for validation of the Global Scales for Early Development (GSED) for children under 3 years of age in seven countries.  13:e062562-e062562. 2023
• Effects of lifestyle interventions on cardiovascular risk factors in South Asians: a systematic review and meta-analysis.  12:e059666-e059666. 2022
• Hospitalised COVID-19 outcomes are predicted by hypoxaemia and pneumonia phenotype irrespective of the timing of their emergence.  12:e062453-e062453. 2022
• Income precarity and child and parent weight change during the COVID-19 pandemic: a cross-sectional analysis of the Ontario Parent Survey.  12:e063653-e063653. 2022
• Prognostic factors for streptococcal toxic shock syndrome: systematic review and meta-analysis.  12:e063023-e063023. 2022
• Understanding discrimination towards persons experiencing homelessness: A scoping review protocol.  12:e066522-e066522. 2022
• Validation of a classification to identify emergency department visits suitable for subacute and virtual care models: a randomised single-blinded agreement study protocol.  12:e068488-e068488. 2022
• Asking youth and adults about child maltreatment: a review of government surveys.  12:e063905-e063905. 2022
• Assessing knowledge, attitudes and belief toward HPV vaccination of parents with children aged 9–14 years in rural communities of Northwest Cameroon: a qualitative study.  12:e068212-e068212. 2022
• Barriers and facilitators to healthy active living in South Asian families in Canada: a thematic analysis.  12:e060385-e060385. 2022
• Characterising performance information use in the primary healthcare systems of El Salvador, Lebanon and Malawi: multiple qualitative case study protocol.  12:e060503-e060503. 2022
• Midodrine therapy for vasopressor dependent shock in the intensive care unit: a protocol for a systematic review and meta-analysis.  12:e064060-e064060. 2022
• Novel care pathway to optimise antimicrobial prescribing for uncomplicated community-acquired pneumonia: study protocol for a prospective before–after cohort study in the emergency department of a tertiary care Canadian children’s hospital.  12:e062360-e062360. 2022
• Canadian Anaphylaxis Network-Predicting Recurrence after Emergency Presentation for Allergic REaction (CAN-PREPARE): a prospective, cohort study protocol.  12:e061976-e061976. 2022
• Cross-sectional survey of the Mental health and Addictions effects, Service impacts and Care needs of children, youth and families during the COVID-19 pandemic: the COVID-19 MASC study protocol.  12:e066190-e066190. 2022
• Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol.  12:e067117-e067117. 2022
• Supporting self-management in women with pre-existing diabetes in pregnancy: a protocol for a mixed-methods sequential comparative case study.  12:e062777-e062777. 2022
• Assessing the sensibility and utility of a short-form version of the HIV Disability Questionnaire in clinical practice settings in Canada, Ireland and the USA: a mixed methods study.  12:e062008-e062008. 2022
• Pharmacotherapy in paediatric type 2 diabetes mellitus: a protocol for a systematic review and network meta-analysis of randomised trials.  12:e065287-e065287. 2022
• Protocol for a qualitative pilot study to explore ethical issues and stakeholder trust in the use of normothermic regional perfusion in organ donation in Canada.  12:e067515-e067515. 2022
• South Asian Youth as Vaccine Agents of Change (SAY-VAC): evaluation of a public health programme to mobilise and empower South Asian youth to foster COVID-19 vaccine-related evidence-based dialogue in the Greater Toronto and Hamilton Area, Canada.  12:e061619-e061619. 2022
• Understanding patient partnership in health systems: lessons from the Canadian patient partner survey.  12:e061465-e061465. 2022
• Understanding patient partnership in health systems: lessons from the Canadian patient partner survey (vol 12, e061465, 2022).  12. 2022
• What are the mental health changes associated with the COVID-19 pandemic in people with medical conditions? An international survey.  12:e060995-e060995. 2022
• Ku-gaa-gii pimitizi-win, the COVID-19 cohort study of people experiencing homelessness in Toronto, Canada: a study protocol.  12:e063234-e063234. 2022
• Cost-free pharmacotherapy in smokers with TIA or stroke: QUIT-MED randomised controlled trial.  12:e050403-e050403. 2022
• Factors Associated with the Magnitude Of acUpuncture treatment effectS (FAMOUS): a meta-epidemiological study of acupuncture randomised controlled trials.  12:e060237-e060237. 2022
• Long-term and serious harms of medical cannabis and cannabinoids for chronic pain: a systematic review of non-randomised studies.  12:e054282-e054282. 2022
• Study protocol for assessing knowledge, attitudes and belief towards HPV vaccination of parents with children aged 9–14 years in rural communities of North West Cameroon: a qualitative study.  12:e062556-e062556. 2022
• Effects of inulin-type fructans supplementation on cardiovascular disease risk factors: a protocol for a systematic review and meta-analysis of randomised controlled trials.  12:e058875-e058875. 2022
• How the Suboxone Education Programme presented as a solution to risks in the Canadian opioid crisis: a critical discourse analysis.  12:e059561-e059561. 2022
• Inclusion of young people with disabilities in the future of work: forecasting workplace, labour market and community-based strategies through an online and accessible Delphi survey protocol.  12:e055452-e055452. 2022
• Protocol for a living systematic review for the management of concussion in adults.  12:e061282-e061282. 2022
• ‘Communication, that is the key’: a qualitative investigation of how essential workers with COVID-19 responded to public health information.  12:e061583-e061583. 2022
• Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study.  12:e057991-e057991. 2022
• Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study.  12:e056400-e056400. 2022
• Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS).  12:e060436-e060436. 2022
• Evaluation of parent and youth experiences in advisory groups as part of a mental healthcare clinical trial: protocol for a mixed-method study.  12:e059689-e059689. 2022
• Evidence mapping and overview of systematic reviews of the effects of acupuncture therapies.  12:e056803-e056803. 2022
• Shorter versus longer durations of antibiotic treatment for patients with community-acquired pneumonia: a protocol for a systematic review and meta-analysis.  12:e062428-e062428. 2022
• Guidance relevant to the reporting of health equity in observational research: a scoping review protocol.  12:e056875-e056875. 2022
• Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP).  12:e058274-e058274. 2022
• Personalised immunotherapy in sepsis: a scoping review protocol.  12:e060411-e060411. 2022
• Primary care-based integrated disease management for heart failure: a study protocol for a cluster randomised controlled trial.  12:e058608-e058608. 2022
• Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit Recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE).  12:e053417-e053417. 2022
• Triple-negative breast cancer prevalence in Africa: a systematic review and meta-analysis.  12:e055735-e055735. 2022
• Aneurysmal subarachnoid haemorrhage—cerebral vasospasm and prophylactic ibuprofen: a randomised controlled pilot trial protocol.  12:e058895-e058895. 2022
• Applying systems thinking to identify enablers and challenges to scale-up interventions for hypertension and diabetes in low-income and middle-income countries: protocol for a longitudinal mixed-methods study.  12:e053122-e053122. 2022
• Assessing the impact of mental health difficulties on young people’s daily lives: protocol for a scoping umbrella review of measurement instruments.  12:e054679-e054679. 2022
• Building knowledge, optimising physical and mental health and setting up healthier life trajectories in South African women (Bukhali): a preconception randomised control trial part of the Healthy Life Trajectories Initiative (HeLTI).  12:e059914-e059914. 2022
• Considerations for developing and implementing an online community-based exercise intervention with adults living with HIV: a qualitative study.  12:e059294-e059294. 2022
• Effect of obesity treatment interventions in preschool children aged 2–6 years: a systematic review and meta-analysis.  12:e053523-e053523. 2022
• Genetics Adviser: a protocol for a mixed-methods randomised controlled trial evaluating a digital platform for genetics service delivery.  12:e060899-e060899. 2022
• Impact of quality improvement initiatives to improve CKD referral patterns: a systematic review protocol.  12:e055456-e055456. 2022
• Implementation of a new clinical and organisational practice to improve access to primary care services: a protocol for an effectiveness-implementation hybrid study.  12:e059792-e059792. 2022
• Implementation strategies to address barriers to evidence-informed symptom management among outpatient oncology nurses: a scoping review protocol.  12:e057661-e057661. 2022
• Intravenous ketorolac versus morphine in children presenting with suspected appendicitis: a pilot single-centre non-inferiority randomised controlled trial.  12:e056499-e056499. 2022
• Prevalence of childhood exposure to intimate partner violence in low-income and lower-middle-income countries: a systematic review.  12:e051140-e051140. 2022
• Qualitative study informing the development and content validity of the HAND-Q: a modular patient-reported outcome measure for hand conditions.  12:e052780-e052780. 2022
• Responsiveness of the HUG-5 in an outpatient clinic: a 12-month randomised feasibility study protocol.  12:e061057-e061057. 2022
• SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada: a cross-sectional study.  12:e057846-e057846. 2022
• Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials.  12:e048502-e048502. 2022
• Cohort profile: genomic data for 26 622 individuals from the Canadian Longitudinal Study on Aging (CLSA).  12:e059021-e059021. 2022
• Defining decision thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks: a protocol for a randomised methodological study (GRADE-THRESHOLD).  12:e053246-e053246. 2022
• Effects of ACE inhibitors and angiotensin receptor blockers: protocol for a UK cohort study using routinely collected electronic health records with validation against the ONTARGET trial.  12:e051907-e051907. 2022
• Feasibility of establishing a Canadian Obstetric Survey System (CanOSS) for severe maternal morbidity: a study protocol.  12:e061093-e061093. 2022
• Fighting COVID-19: a qualitative study into the lives of intensive care unit survivors in Wuhan, China.  12:e055365-e055365. 2022
• Investigating the role and applicability of patient versions of guidelines in oncology and deriving recommendations for the development, dissemination and implementation of patient versions in Germany: protocol for multiphase study.  12:e059040-e059040. 2022
• Long COVID and episodic disability: advancing the conceptualisation, measurement and knowledge of episodic disability among people living with Long COVID – protocol for a mixed-methods study.  12:e060826-e060826. 2022
• Primary Care Severe Asthma Registry and Education Project (PCSAR-EDU): Phase 1 – an e-Delphi for registry definitions and indices of clinician behaviour.  12:e055958-e055958. 2022
• Randomised comparative effectiveness trial of Pulmonary Embolism Prevention after hiP and kneE Replacement (PEPPER): the PEPPER trial protocol.  12:e060000-e060000. 2022
• Telerehabilitation for lower extremity recovery poststroke: a systematic review and meta-analysis protocol.  12:e055527-e055527. 2022
• Bedtime versus morning use of antihypertensives for cardiovascular risk reduction (BedMed): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial.  12:e059711-e059711. 2022
• Characteristics and quality of clinical practice guidelines addressing acupuncture interventions: a systematic survey of 133 guidelines and 433 acupuncture recommendations.  12:e058834-e058834. 2022
• Comparative efficacy and safety of alternative glucocorticoids regimens in patients with ANCA-associated vasculitis: a systematic review.  12:e050507-e050507. 2022
• Cross-sectional prospective feasibility study of newborn screening for sickle cell anaemia and congenital hypothyroidism in Guyana.  12:e046240-e046240. 2022
• Development of a core outcome set for multimorbidity trials in low/middle-income countries (COSMOS): study protocol.  12:e051810-e051810. 2022
• Families’ healthcare experiences for children with inherited metabolic diseases: protocol for a mixed methods cohort study.  12:e055664-e055664. 2022
• Feasibility of implementing the advanced HIV disease care package as part of community-based HIV/TB activities: a mixed-methods study protocol.  12:e057291-e057291. 2022
• Global status of essential medicine selection: a systematic comparison of national essential medicine lists with recommendations by WHO.  12:e053349-e053349. 2022
• Impact of virtual care on health-related quality of life in children with diabetes mellitus: a systematic review protocol.  12:e053642-e053642. 2022
• Qualitative analysis of a virtual research meeting summarises expert-based strategies to promote hydration in residential care during COVID-19 and beyond.  12:e055457-e055457. 2022
• Tranexamic acid versus placebo to reduce perioperative blood transfusion in patients undergoing liver resection: protocol for the haemorrhage during liver resection tranexamic acid (HeLiX) randomised controlled trial.  12:e058850-e058850. 2022
• Understanding income-related differences in distribution of child growth, behaviour and development using a cross-sectional sample of a clinical cohort study.  12:e056991-e056991. 2022
• Associations of functional disability and behavioural risk factors with social participation of older adults: a cross-sectional analysis from the Canadian Longitudinal Study on Aging.  12:e052173-e052173. 2022
• Clinical outcome measures and their evidence base in degenerative cervical myelopathy: a systematic review to inform a core measurement set (AO Spine RECODE-DCM).  12:e057650-e057650. 2022
• Do baseline characteristics and treatments account for geographical disparities in the outcomes of patients with newly diagnosed atrial fibrillation? The prospective GARFIELD-AF registry.  12:e049933-e049933. 2022
• Evaluation of a decision aid for incidental genomic results, the Genomics ADvISER: protocol for a mixed methods randomised controlled trial.  8:e021876-e021876. 2022
• Investigating the work–life experiences of nursing faculty in Canadian academic settings and the factors that influence their retention: protocol for a mixed-method study.  12:e056655-e056655. 2022
• Sacrifice and solidarity: a qualitative study of family experiences of death and bereavement in critical care settings during the pandemic.  12:e058768-e058768. 2022
• Background incidence rates of hospitalisations and emergency department visits for thromboembolic and coagulation disorders in Ontario, Canada for COVID-19 vaccine safety assessment: a population-based retrospective observational study.  11:e052019-e052019. 2021
• CCEDRRN COVID-19 Infection Score (CCIS): development and validation in a Canadian cohort of a clinical risk score to predict SARS-CoV-2 infection in patients presenting to the emergency department with suspected COVID-19.  11:e055832-e055832. 2021
• CCWORK protocol: a longitudinal study of Canadian Correctional Workers’ Well-being, Organizations, Roles and Knowledge.  11:e052739-e052739. 2021
• Current practices and challenges in adaptation of clinical guidelines: a qualitative study based on semistructured interviews.  11:e053587-e053587. 2021
• Detecting young people with mental disorders: a cluster-randomised trial of multidisciplinary health teams at the GP office.  11:e050036-e050036. 2021
• Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort study.  11:e053021-e053021. 2021
• Identifying patient characteristics associated with potentially redirectable paramedic transported emergency department visits in Ontario, Canada: a population-based cohort study.  11:e054625-e054625. 2021
• Identifying patient-important outcomes for treatment of bipolar disorder: a systematic review protocol.  11:e050453-e050453. 2021
• Impact of COVID-19 on mobility and participation of older adults living in Hamilton, Ontario, Canada: a multimethod cohort design protocol.  11:e053758-e053758. 2021
• Public health implications of SARS-CoV-2 variants of concern: a rapid scoping review.  11:e055781-e055781. 2021
• Association of chiropractic integration in an Ontario community health centre with prescription opioid use for chronic non-cancer pain: a mixed methods study protocol.  11:e051000-e051000. 2021
• Kukaa Salama (Staying Safe): study protocol for a pre/post-trial of an interactive mHealth intervention for increasing COVID-19 prevention practices with urban refugee youth in Kampala, Uganda.  11:e055530-e055530. 2021
• Optimising a couples-focused intervention to increase couples’ HIV testing and counselling using the person-based approach: a qualitative study in Kwa-Zulu Natal, South Africa.  11:e047408-e047408. 2021
• Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study.  11:e050830-e050830. 2021
• Outcomes reported in randomised controlled trials of major depressive disorder in older adults: protocol for a methodological review.  11:e054777-e054777. 2021
• Quality indicators for transition from paediatric to adult care for adolescents with chronic physical and mental illness: protocol for a systematic review.  11:e055194-e055194. 2021
• Rates of opioid agonist treatment prescribing in provincial prisons in Ontario, Canada, 2015–2018: a repeated cross-sectional analysis.  11:e048944-e048944. 2021
• Relevance of assessment items in community paramedicine home visit programmes: results of a modified Delphi study.  11:e048504-e048504. 2021
• Trajectory research in children on the autism spectrum: a scoping review protocol.  11:e053443-e053443. 2021
• Unravelling data for rapid evidence-based response to COVID-19: a summary of the unCoVer protocol.  11:e055630-e055630. 2021
• Gastrointestinal recovery after surgery: protocol for a systematic review.  11:e054704-e054704. 2021
• Impact of electronic cigarette ever use on lung function in adults aged 45–85: a cross-sectional analysis from the Canadian Longitudinal Study on Aging.  11:e051519-e051519. 2021
• Relationship between hormonal contraceptives and sleep among women of reproductive age: a systematic review protocol.  11:e045819-e045819. 2021
• Values and other decisional factors regarding treatment of hypercalcaemia of malignancy: a systematic review protocol.  11:e051141-e051141. 2021
• Virological measures and factors associated with outcomes, and missing outcome data in HIV clinical trials: a methodological study.  11:e039462-e039462. 2021
• Youth in a pandemic: a longitudinal examination of youth mental health and substance use concerns during COVID-19.  11:e049209-e049209. 2021
• Cohort profile: the Ontario Life After Workplace Injury Study (OLAWIS).  11:e048143-e048143. 2021
• Diagnostic and prognostic accuracy of Protein C in adult patients with sepsis: protocol for a systematic review and meta-analysis.  11:e050754-e050754. 2021
• Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: a systematic integrative review.  11:e047511-e047511. 2021
• Impact of restricted visitation policies in hospitals on patients, family members and healthcare providers during the COVID-19 pandemic: a scoping review protocol.  11:e048227-e048227. 2021
• Investigating and addressing the immediate and long-term consequences of the COVID-19 pandemic on patients with substance use disorders: a scoping review and evidence map protocol.  11:e045946-e045946. 2021
• Life or limb: an international qualitative study on decision making in sarcoma surgery during the COVID-19 pandemic.  11:e047175-e047175. 2021
• MUFFIN-PTS trial, Micronized Purified Flavonoid Fraction for the Treatment of Post-Thrombotic Syndrome: protocol of a randomised controlled trial.  11:e049557-e049557. 2021
• Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in severely bleeding trauma patients: the FiiRST 2 trial (a 2020 EAST multicentre trial).  11:e051003-e051003. 2021
• Publication practices of sub-Saharan African Cochrane authors: a bibliometric study.  11:e051839-e051839. 2021
• Ross for Valve replacement In AduLts (REVIVAL) pilot trial: rationale and design of a randomised controlled trial.  11:e046198-e046198. 2021
• Values and preferences towards medical cannabis among people living with chronic pain: a mixed-methods systematic review.  11:e050831-e050831. 2021
• Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysis.  11:e053302-e053302. 2021
• Identifying non-traditional electronic datasets for population-level surveillance and prevention of cardiometabolic diseases: a scoping review protocol.  11:e053485-e053485. 2021
• Intimate partner violence (IPV) in male and female orthopaedic trauma patients: a multicentre, cross-sectional prevalence study.  11:e046164-e046164. 2021
• Single-centre, open-label, randomised, trial to compare rapid molecular point-of-care streptococcal testing to standard laboratory-based testing for the management of streptococcal pharyngitis in children: study protocol.  11:e047271-e047271. 2021
• Sleep, biological rhythms and anxiety in the perinatal period: a systematic review protocol.  11:e046767-e046767. 2021
• COVID-19 international border surveillance at Toronto’s Pearson Airport: a cohort study.  11:e050714-e050714. 2021
• Coached, Coordinated, Enhanced Neonatal Transition (CCENT): protocol for a multicentre pragmatic randomised controlled trial of transition-to-home support for parents of high-risk infants.  11:e046706-e046706. 2021
• Consideration of antimicrobial resistance and contextual factors in infectious disease guidelines: a systematic survey.  11:e046097-e046097. 2021
• Experiences engaging in a group-based physiotherapist-led exercise programme for adults living with HIV and complex multimorbidity: a qualitative study.  11:e045158-e045158. 2021
• Frailty differences across population characteristics associated with health inequality: a cross-sectional analysis of baseline data from the Canadian Longitudinal Study on Aging (CLSA).  11:e047945-e047945. 2021
• Hands-Up program: protocol for a feasibility randomised controlled trial of a combined 6-week exercise and education intervention in adults aged 50–65 with a distal radius fracture.  11:e046122-e046122. 2021
• Interventional treatments for chronic, axial or radicular, non-cancer, spinal pain: a protocol for a systematic review and network meta-analysis of randomised trials.  11:e046025-e046025. 2021
• Management of social isolation and loneliness in community-dwelling older adults: protocol for a network meta-analysis of randomised controlled trials.  11:e042828-e042828. 2021
• Opioid-sparing effects of medical cannabis or cannabinoids for chronic pain: a systematic review and meta-analysis of randomised and observational studies.  11:e047717-e047717. 2021
• Programmes to prepare siblings for future roles to support their brother or sister with a neurodisability: protocol of a scoping review.  11:e053184-e053184. 2021
• Risk assessment models for venous thromboembolism in hospitalised adult patients: a systematic review.  11:e045672-e045672. 2021
• Simulation study on the validity of the average risk approach in estimating population attributable fractions for continuous exposures.  11:e045410-e045410. 2021
• Systematic review of academic bullying in medical settings: dynamics and consequences.  11:e043256-e043256. 2021
• Values, preferences and burden of treatment for the initiation of GLP-1 receptor agonists and SGLT-2 inhibitors in adult patients with type 2 diabetes: a systematic review.  11:e049130-e049130. 2021
• Which older emergency patients are at risk of intracranial bleeding after a fall? A protocol to derive a clinical decision rule for the emergency department.  11:e044800-e044800. 2021
• Mixed-methods study protocol for an evaluation of the mental health transition navigator model in child and adolescent mental health services: the Navigator Evaluation Advancing Transitions (NEAT) study.  11:e051190-e051190. 2021
• Progression from external pilot to definitive randomised controlled trial: a methodological review of progression criteria reporting.  11:e048178-e048178. 2021
• Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units.  11:e046909-e046909. 2021
• Association between end-of-life cancer care and immigrant status: a retrospective cohort study in Ontario, Canada.  11:e042978-e042978. 2021
• Impact of disasters, including pandemics, on cardiometabolic outcomes across the life-course: a systematic review.  11:e047152-e047152. 2021
• LIVES for families psychological first aid training programme to address COVID-19 psychological distress: A mixed methods acceptability and feasibility protocol.  11:e049995-e049995. 2021
• Physical-mental multimorbidity in children and youth: a scoping review.  11:e043124-e043124. 2021
• Transforming primary care for older Canadians living with frailty: mixed methods study protocol for a complex primary care intervention.  11:e042911-e042911. 2021
• Association between postsurgical pain and heart rate variability: protocol for a scoping review.  11:e044949-e044949. 2021
• Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol.  11:e046851-e046851. 2021
• Determinants of short birth intervals among married women: a cross-sectional study in Karachi, Pakistan.  11:e043786-e043786. 2021
• Impact of neighbourhood walkability on the onset of multimorbidity: a cohort study.  11:e045890-e045890. 2021
• Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE).  11:e049093-e049093. 2021
• Virtual care for prostate cancer survivorship: protocol for an evaluation of a nurse-led algorithm-enhanced virtual clinic implemented at five cancer centres across Canada.  11:e045806-e045806. 2021
• Web-based early intervention for children with motor difficulties aged 3–8 years old using multimodal rehabilitation (WECARE): protocol of a patient-centred pragmatic randomised trial of paediatric telerehabilitation to support families.  11:e046561-e046561. 2021
• Effects of cosmetic and other camouflage interventions on appearance-related and psychological outcomes among adults with visible differences in appearance: a systematic review..  11:e046634. 2021
• CHILD-BRIGHT READYorNot Brain-Based Disabilities Trial: protocol of a randomised controlled trial (RCT) investigating the effectiveness of a patient-facing e-health intervention designed to enhance healthcare transition readiness in youth.  11:e048756-e048756. 2021
• Decision Analysis in SHared decision making for Thromboprophylaxis during Pregnancy (DASH-TOP): a sequential explanatory mixed methods pilot study protocol.  11:e046021-e046021. 2021
• HIV prevention and treatment interventions for black men who have sex with men in Canada: a protocol for a scoping systematic review.  11:e043055-e043055. 2021
• Repetitive transcranial magnetic stimulation alone and in combination with motor control exercise for the treatment of individuals with chronic non-specific low back pain (ExTraStim trial): study protocol for a randomised controlled trial.  11:e045504-e045504. 2021
• Risk of dispersion or aerosol generation and infection transmission with nasopharyngeal and oropharyngeal swabs for detection of COVID-19: a systematic review.  11:e040616-e040616. 2021
• Staying ahead of the curve: Navigating changes and maintaining gains in patient safety culture - a mixed-methods study.  11:e044116-e044116. 2021
• Deprescribing fall-risk increasing drugs (FRIDs) for the prevention of falls and fall-related complications: a systematic review and meta-analysis.  11:e035978-e035978. 2021
• Do premorbid characteristics of home care clients predict delayed discharges in acute care hospitals: a retrospective cohort study in Ontario and British Columbia, Canada.  11:e038484-e038484. 2021
• End-of-life outcomes with or without early palliative care: a propensity score matched, population-based cancer cohort study.  11:e041432-e041432. 2021
• Patient-specific instrumentation (PSI) Referencing High Tibial Osteotomy Technological Transfer and Education: protocol for a double-blind, randomised controlled trial (PROTECTED HTO Trial).  11:e041129-e041129. 2021
• Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally—Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): a Healthy Life Trajectories Initiative (HeLTI) Study.  11:e045862-e045862. 2021
• Protocol for a randomised trial evaluating a preconception-early childhood telephone-based intervention with tailored e-health resources for women and their partners to optimise growth and development among children in Canada: a Healthy Life Trajectory Initiative (HeLTI Canada).  11:e046311-e046311. 2021
• Willingness of patients with sarcoma to participate in cancer surveillance research: a cross-sectional patient survey.  11:e042742-e042742. 2021
• Disclosure of study funding and author conflicts of interest in press releases and the news: a retrospective content analysis with two cohorts..  11:e041385. 2021
• Are patients’ goals in treatment associated with expected treatment outcomes? Findings from a mixed-methods study on outpatient pharmacological treatment for opioid use disorder.  11:e044017-e044017. 2021
• Association between vaping and health outcomes in patients with opioid use disorder: a systematic review protocol.  11:e040349-e040349. 2021
• Barriers, facilitators, preferences and expectations of joint protection programmes for patients with hand arthritis: a cross-sectional survey.  11:e041935-e041935. 2021
• Development of the PriCARE classification for potentially preventable emergency department visits by ambulance: a RAND/UCLA modified Delphi study protocol.  11:e045351-e045351. 2021
• Which Exercise for Low Back Pain? (WELBack) trial predicting response to exercise treatments for patients with low back pain: a validation randomised controlled trial protocol.  11:e042792-e042792. 2021
• Adaptive randomised controlled non-inferiority multicentre trial (the Ketodex Trial) on intranasal dexmedetomidine plus ketamine for procedural sedation in children: study protocol.  10:e041319-e041319. 2020
• Establishing thresholds for important benefits considering the harms of screening interventions.  10:e037854-e037854. 2020
• How do cancer screening guidelines trade off benefits versus harms and burdens of screening? A systematic survey.  10:e038322-e038322. 2020
• Introduction to statistical simulations in health research.  10:e039921-e039921. 2020
• National primary care responses to COVID-19: a rapid review of the literature.  10:e041622-e041622. 2020
• Protocol for a scoping review of outcomes in clinical studies of interventions for venous thromboembolism in adults.  10:e040122-e040122. 2020
• Reporting of methodological studies in health research: a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC).  10:e040478-e040478. 2020
• Are you really doing ‘codesign’? Critical reflections when working with vulnerable populations.  10:e038339-e038339. 2020
• Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial.  10:e040110-e040110. 2020
• Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65): protocol and statistical analysis plan for a randomised clinical trial.  10:e037947-e037947. 2020
• Use of implementation science in tobacco control intervention studies in the USA between 2000 and 2020: a scoping review protocol.  10:e038617-e038617. 2020
• Cross-sectional analysis of bibliometrics and altmetrics: comparing the impact of qualitative and quantitative articles in the British Medical Journal..  10:e040950. 2020
• Cost-effectiveness analysis of a community paramedicine programme for low-income seniors living in subsidised housing: the community paramedicine at clinic programme (CP@clinic).  10:e037386-e037386. 2020
• IMAGINE Network’s Mind And Gut Interactions Cohort (MAGIC) Study: a protocol for a prospective observational multicentre cohort study in inflammatory bowel disease and irritable bowel syndrome.  10:e041733-e041733. 2020
• Identifying factors associated with high use of acute care in Canada: protocol of a population-based retrospective cohort study.  10:e038008-e038008. 2020
• Predicting population health with machine learning: a scoping review.  10:e037860-e037860. 2020
• Reproductive patterns, pregnancy outcomes and parental leave practices of women physicians in Ontario, Canada: the Dr Mom Cohort Study protocol.  10:e041281-e041281. 2020
• Social determinants of health associated with the development of sepsis in adults: a scoping review protocol.  10:e039146-e039146. 2020
• Trial of remote ischaemic preconditioning in vascular cognitive impairment (TRIC-VCI): protocol.  10:e040466-e040466. 2020
• Critical review of multimorbidity outcome measures suitable for low-income and middle-income country settings: perspectives from the Global Alliance for Chronic Diseases (GACD) researchers.  10:e037079-e037079. 2020
• How and why a multifaceted intervention to improve adherence post-MI worked for some (and could work better for others): an outcome-driven qualitative process evaluation.  10:e036750-e036750. 2020
• Impact of COVID-19 and other pandemics and epidemics on people with pre-existing mental disorders: a systematic review protocol and suggestions for clinical care.  10:e040229-e040229. 2020
• Multicentre, single-blind randomised controlled trial comparing MyndMove neuromodulation therapy with conventional therapy in traumatic spinal cord injury: a protocol study.  10:e039650-e039650. 2020
• Overview of systematic reviews on strategies to improve treatment initiation, adherence to antiretroviral therapy and retention in care for people living with HIV: part 1.  10:e034793-e034793. 2020
• Predictors of oral anticoagulant-associated adverse events in seniors transitioning from hospital to home: a retrospective cohort study protocol.  10:e036537-e036537. 2020
• Adaptive design methods in dialysis clinical trials: a systematic review protocol.  10:e036755-e036755. 2020
• Barriers and facilitators to optimal supportive end-of-life palliative care in long-term care facilities: a qualitative descriptive study of community-based and specialist palliative care physicians’ experiences, perceptions and perspectives.  10:e037466-e037466. 2020
• Barriers in accessing HIV care for Francophone African, Caribbean and Black people living with HIV in Canada: a scoping review.  10:e036885-e036885. 2020
• Do insomnia and/or sleep disturbances predict the onset, relapse or worsening of depression in community and clinical samples of children and youth? Protocol for a systematic review and meta-analysis.  10:e034606-e034606. 2020
• Health programmes and services addressing the prevention and management of infectious diseases in persons who inject drugs in Canada: a systematic integrative review protocol.  10:e035188-e035188. 2020
• Protocol of an interdisciplinary consensus project aiming to develop an AGREE II extension for guidelines in surgery.  10:e037107-e037107. 2020
• A/C study protocol: a cross-sectional study of HIV epidemiology among African, Caribbean and Black people in Ontario.  10:e036259-e036259. 2020
• Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada.  10:e033932-e033932. 2020
• Core outcome set for studies on pregnant women with vasa previa (COVasP): a study protocol.  10:e034018-e034018. 2020
• Development of a core outcome set for studies on prevention and management of pregnancy-associated venous thromboembolism (COSPVenTE): a study protocol.  10:e034017-e034017. 2020
• National suicide management guidelines with family as an interv’ention and suicide mortality rates: a systematic review protocol.  10:e034694-e034694. 2020
• Provision of medical assistance in dying: a scoping review.  10:e036054-e036054. 2020
• Reporting of conflicts of interest by authors of primary studies on health policy and systems research: a cross-sectional survey.  10:e032425-e032425. 2020
• Systematic survey of the causal language use in systematic reviews of observational studies: a study protocol.  10:e038571-e038571. 2020
• Trajectories of health system use and survival for community-dwelling persons with dementia: a cohort study.  10:e037485-e037485. 2020
• Assessing the transparency of informed consent in feasibility and pilot studies: a single-centre quality assurance study protocol.  10:e036226-e036226. 2020
• Concurrent validity of the alcohol purchase task in relation to alcohol involvement: protocol for a systematic review and meta-analysis.  10:e035400-e035400. 2020
• Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol.  10:e036047-e036047. 2020
• How have predictors, moderators, mediators, treatment response, remission and resistance been defined and measured in randomised controlled trials for adolescent depression? A scoping review protocol.  10:e036171-e036171. 2020
• Improving gender equity in critical care medicine: a protocol to establish priorities and strategies for implementation.  10:e037090-e037090. 2020
• Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives.  10:e037527-e037527. 2020
• Psychometric properties of an Arabic-language health literacy assessment scale for adolescents (HAS-A-AR) in Palestine.  10:e034943-e034943. 2020
• Study protocol for two complementary trials of non-steroidal or opioid analgesia use for children aged 6 to 17 years with musculoskeletal injuries (the No OUCH study).  10:e035177-e035177. 2020
• Assessing care models implemented in primary healthcare for persons with dementia: a mixed-methods study protocol.  10:e035916-e035916. 2020
• Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol.  10:e038300-e038300. 2020
• Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey.  10:e034565-e034565. 2020
• Cow’s Milk Fat Obesity pRevention Trial (CoMFORT): a primary care embedded randomised controlled trial protocol to determine the effect of cow’s milk fat on child adiposity.  10:e035241-e035241. 2020
• Collaborating with healthcare providers to understand their perspectives on a hospital-to-home warning signs intervention for rural transitional care: protocol of a multimethod descriptive study.  10:e034698-e034698. 2020
• Socioeconomic gradient in the developmental health of Canadian children with disabilities at school entry: a cross-sectional study.  10:e032396-e032396. 2020
• [¹⁸F]DCFPyL PET-MRI/CT for unveiling a molecularly defined oligorecurrent prostate cancer state amenable for curative-intent ablative therapy: study protocol for a phase II trial.  10:e035959-e035959. 2020
• Development and usability testing of HEARTPA♀N: protocol for a mixed methods strategy to develop an integrated smartphone and web-based intervention for women with cardiac pain.  10:e033092-e033092. 2020
• Evaluating a group-based Yoga of Stress Resilience programme: a pragmatic before–after interventional study protocol.  10:e035862-e035862. 2020
• Impact of a short version of the CONSORT checklist for peer reviewers to improve the reporting of randomised controlled trials published in biomedical journals: study protocol for a randomised controlled trial.  10:e035114-e035114. 2020
• International mixed methods study protocol to develop a patient-reported outcome measure for all types of chronic wounds (the WOUND-Q).  10:e032332-e032332. 2020
• Pain Squad+ smartphone app to support real-time pain treatment for adolescents with cancer: protocol for a randomised controlled trial.  10:e037251-e037251. 2020
• Chronic disease management models in nursing homes: a scoping review.  10:e032316-e032316. 2020
• Effects of medical and non-medical cannabis use in older adults: protocol for a scoping review.  10:e034301-e034301. 2020
• Impact of the KidneyWise toolkit on chronic kidney disease referral practices in Ontario primary care: a prospective evaluation.  10:e032838-e032838. 2020
• Longitudinal Youth in Transition Study (LYiTS): protocol for a multicentre prospective cohort study of youth transitioning out of child and adolescent mental health services at age 18.  10:e035744-e035744. 2020
• Developing a framework to incorporate real-world evidence in cancer drug funding decisions: the Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration.  10:e032884-e032884. 2020
• Effectiveness of non-pharmacological strategies in the management of type 2 diabetes in primary care: a protocol for a systematic review and network meta-analysis.  10:e034481-e034481. 2020
• Guidelines about physical activity and exercise to reduce cardiometabolic risk factors: protocol for a systematic review and critical appraisal.  10:e032656-e032656. 2020
• International phase 1 study protocol to develop a health state classification system for a preference-based measure for women with breast cancer: the BREAST-Q Utility module.  10:e034451-e034451. 2020
• Sex-specific effects of nutritional supplements in infants born early or small: protocol for an individual participant data meta-analysis (ESSENCE IPD-MA).  10:e033438-e033438. 2020
• Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study.  9:e035206-e035206. 2019
• DIVERT-Collaboration Action Research and Evaluation (CARE) Trial Protocol: a multiprovincial pragmatic cluster randomised trial of cardiorespiratory management in home care.  9:e030301-e030301. 2019
• Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol.  9:e034594-e034594. 2019
• Role of patient preferences in clinical practice guidelines: a multiple methods study using guidelines from oncology as a case.  9:e032483-e032483. 2019
• Safety and efficacy of perioperative benzodiazepine administration: study protocol for a systematic review and meta-analysis.  9:e031895-e031895. 2019
• Sleep duration and eating behaviours in youth: a scoping review protocol.  9:e030457-e030457. 2019
• Transitional care quality indicators to assess quality of care following hospitalisation for chronic obstructive pulmonary disease and heart failure: a systematic review protocol.  9:e032764-e032764. 2019
• Estimation of fibrosis progression rates for chronic hepatitis C: a systematic review and meta-analysis update.  9:e027491-e027491. 2019
• Fit for School Study protocol: early child growth, health behaviours, nutrition, cardiometabolic risk and developmental determinants of a child’s school readiness, a prospective cohort.  9:e030709-e030709. 2019
• Fostering humanism: a mixed methods evaluation of the Footprints Project in critical care.  9:e029810-e029810. 2019
• Multifaceted intervention to Reduce Antimicrobial Prescribing in Care Homes: a process evaluation of a UK-based non-randomised feasibility study.  9:e032185-e032185. 2019
• Multimorbidity in Children and Youth Across the Life-course (MY LIFE): protocol of a Canadian prospective study.  9:e034544-e034544. 2019
• Protocol for a double-blind, randomised, placebo-controlled pilot study for assessing the feasibility and efficacy of faecal microbiota transplant in a paediatric Crohn’s disease population: PediCRaFT Trial.  9:e030120-e030120. 2019
• Psychometric properties of the global rating of change scales in patients with neck disorders: a systematic review with meta-analysis and meta-regression.  9:e033909-e033909. 2019
• Systematic review of the measurement properties of performance-based functional tests in patients with neck disorders.  9:e031242-e031242. 2019
• Examining consensus for a standardised patient assessment in community paramedicine home visits: a RAND/UCLA-modified Delphi Study.  9:e031956-e031956. 2019
• Feasibility and implementation of a healthy lifestyles program in a community setting in Ontario, Canada: protocol for a pragmatic mixed methods pilot study.  9:e031298-e031298. 2019
• Incremental healthcare utilisation and costs among new senior high-cost users in Ontario, Canada: a retrospective matched cohort study.  9:e028637-e028637. 2019
• Optimised transcranial direct current stimulation (tDCS) for fibromyalgia—targeting the endogenous pain control system: a randomised, double-blind, factorial clinical trial protocol.  9:e032710-e032710. 2019
• Regional variation in primary care improvement strategies and policy: case studies that consider qualitative contextual data for performance measurement in three Canadian provinces.  9:e029622-e029622. 2019
• Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry qualitative study.  9:e032166-e032166. 2019
• How patient acceptability affects access to breast reconstruction: a qualitative study..  9:e029048. 2019
• Choosing appropriate tools and referral criteria for vision screening of children aged 4–5 years in Canada: a quantitative analysis.  9:e032138-e032138. 2019
• Cohort profile: the Canadian coordination and activity tracking in children (CATCH) longitudinal cohort.  9:e029784-e029784. 2019
• Comparison of ventilatory modes to facilitate liberation from mechanical ventilation: protocol for a systematic review and network meta-analysis.  9:e030407-e030407. 2019
• Decision support intervention (Plan Well Guide) for patients and their substitute decision-makers to improve engagement in advance care planning: protocol for a randomised trial.  9:e027897-e027897. 2019
• Effects of accelerated versus standard care surgery on the risk of acute kidney injury in patients with a hip fracture: a substudy protocol of the hip fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) international randomised controlled trial.  9:e033150-e033150. 2019
• Empirical evaluation of SUCRA-based treatment ranks in network meta-analysis: quantifying robustness using Cohen’s kappa.  9:e024625-e024625. 2019
• Evaluating the endometabolic and bone health effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukaemia: a systematic review protocol.  9:e030092-e030092. 2019
• Extending the RIGHT statement for reporting adapted practice guidelines in healthcare: the RIGHT-Ad@pt Checklist protocol.  9:e031767-e031767. 2019
• Risk of myocardial infarction among people living with HIV: an updated systematic review and meta-analysis.  9:e025874-e025874. 2019
• The Surveillance After Extremity Tumor Surgery (SAFETY) trial: protocol for a pilot study to determine the feasibility of a multi-centre randomised controlled trial.  9:e029054-e029054. 2019
• Tranexamic acid in cardiac surgery: a systematic review and meta-analysis (protocol).  9:e028585-e028585. 2019
• Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study.  9:e031775-e031775. 2019
• Complex care for kids Ontario: protocol for a mixed-methods randomised controlled trial of a population-level care coordination initiative for children with medical complexity.  9:e028121-e028121. 2019
• Educational virtual reality videos in improving bowel preparation quality and satisfaction of outpatients undergoing colonoscopy: protocol of a randomised controlled trial.  9:e029483-e029483. 2019
• Effectiveness and safety of Chinese herbal medicine xuanbi antong granules for the treatment of borderline coronary lesions: study protocol for a randomised, double-blinded, placebo-controlled, multicentre clinical trial.  9:e024968-e024968. 2019
• Living strategies for disability in men ageing with HIV in Ontario, Canada: a longitudinal qualitative study.  9:e031262-e031262. 2019
• Readmission and processes of care across weekend and weekday hospitalisation for acute myocardial infarction, heart failure or stroke: an observational study of the National Readmission Database.  9:e029667-e029667. 2019
• Taking an integrated knowledge translation approach in research to develop the CONSORT-Equity 2017 reporting guideline: an observational study..  9:e026866. 2019
• Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients (COMIC): a pilot randomised controlled trial protocol.  9:e029394-e029394. 2019
• Development of a point of care system for automated coma prognosis: a prospective cohort study protocol.  9:e029621-e029621. 2019
• Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness.  9:e027893-e027893. 2019
• Women with physical disability in pregnancy resident education: a national survey as a needs assessment for curriculum improvement in obstetrics and gynaecology in Canada.  9:e024505-e024505. 2019
• Nash-wo-Numa(childhood growth & development) study protocol: factors that impact linear growth in children 9 to 15 years of age in Matiari, Pakistan.  9:e028343-e028343. 2019
• DONORS (Donation Network to Optimise Organ Recovery Study): Study protocol to evaluate the implementation of an evidence-based checklist for brain-dead potential organ donor management in intensive care units, a cluster randomised trial.  9:e028570-e028570. 2019
• Defining certainty of net benefit: a GRADE concept paper.  9:e027445-e027445. 2019
• Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study.  9:e028237-e028237. 2019
• Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT.  9:e025228-e025228. 2019
• Impact of smoking on health system costs among cancer patients in a retrospective cohort study in Ontario, Canada.  9:e026022-e026022. 2019
• Perceptions of older adults in Ontario, Canada on the implementation and impact of a primary care programme, Health Teams Advancing Patient Experience: Strengthening Quality (Health TAPESTRY): a descriptive qualitative study.  9:e026257-e026257. 2019
• Psychological correlates and binge drinking behaviours among Canadian youth: a cross-sectional analysis of the mental health pilot data from the COMPASS study.  9:e028558-e028558. 2019
• Public, health professional and legislator perspectives on the concept of psychiatric disease: a population-based survey.  9:e024265-e024265. 2019
• A methodological survey on reporting of pilot and feasibility trials for physiotherapy interventions: a study protocol.  9:e020580-e020580. 2019
• Accounting for health literacy and intervention preferences when reducing unhealthy snacking: protocol for an online randomised controlled trial.  9:e028544-e028544. 2019
• Acute and long-term clinical, neuropsychological and return-to-work sequelae following electrical injury: a retrospective cohort study.  9:e025990-e025990. 2019
• Anti-vascular endothelial growth factor treatment for retinal conditions: a systematic review and meta-analysis.  9:e022031-e022031. 2019
• Effect of cervical manipulation on vertebral artery and cerebral haemodynamics in patients with chronic neck pain: a crossover randomised controlled trial.  9:e025219-e025219. 2019
• Effectiveness of interventions for the implementation of thromboprophylaxis in hospitalised patients at risk of venous thromboembolism: an updated abridged Cochrane systematic review and meta-analysis of randomised controlled trials.  9:e024444-e024444. 2019
• Herbal medications for anxiety, depression, pain, nausea and vomiting related to preoperative surgical patients: a systematic review and meta-analysis of randomised controlled trials.  9:e023729-e023729. 2019
• Important food sources of fructose-containing sugars and incident gout: a systematic review and meta-analysis of prospective cohort studies.  9:e024171-e024171. 2019
• International multiphase mixed methods study protocol to develop a patient-reported outcome instrument for children and adolescents with lower limb deformities.  9:e027079-e027079. 2019
• Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC).  9:e028698-e028698. 2019
• Pedagogical strategies in teaching invasive prenatal procedures: a scoping review protocol.  9:e024629-e024629. 2019
• Perioperative Pain and Addiction Interdisciplinary Network (PAIN): protocol of a practice advisory for the perioperative management of buprenorphine using a modified Delphi process.  9:e027374-e027374. 2019
• Recommendations for integrating physiotherapy into an interprofessional outpatient care setting for people living with HIV: a qualitative study.  9:e026827-e026827. 2019
• Transepithelial versus epithelium-off corneal collagen cross-linking for corneal ectasia: protocol for a systematic review, meta-analysis and trial sequential analysis of randomised controlled trials.  9:e025728-e025728. 2019
• Children’s and caregivers’ perspectives about mandatory reporting of child maltreatment: a meta-synthesis of qualitative studies.  9:e025741-e025741. 2019
• How do financial (dis)incentives influence health behaviour and costs? Protocol for a systematic literature review of randomised controlled trials.  9:e024694-e024694. 2019
• Management of acute musculoskeletal pain (excluding low back pain): protocol for a systematic review and network meta-analysis of randomised trials.  9:e024441-e024441. 2019
• Multifactorial correlates of blood pressure in South Asian children in Canada: a cross-sectional study.  9:e027844-e027844. 2019
• Qualitative descriptive study to explore nurses’ perceptions and experience on pain, agitation and delirium management in a community intensive care unit.  9:e024328-e024328. 2019
• Rationale and design of the HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial: a protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients.  9:e028537-e028537. 2019
• What factors are associated with resilient outcomes in children exposed to social adversity? A systematic review.  9:e024870-e024870. 2019
• Knowledge and motivations of researchers publishing in presumed predatory journals: a survey..  9:e026516. 2019
• Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study.  9:e024159-e024159. 2019
• Children and Teens in Charge of their Health (CATCH): A protocol for a feasibility randomised controlled trial of solution-focused coaching to foster healthy lifestyles in childhood disability.  9:e025119-e025119. 2019
• Effectiveness of the Diagnose-Intervene- Verify-Adjust (DIVA) model for integrated primary healthcare planning and performance improvement: an embedded mixed methods evaluation in Kaduna state, Nigeria.  9:e026016-e026016. 2019
• Experiences of community-dwelling older adults living with multiple chronic conditions: a qualitative study.  9:e023345-e023345. 2019
• International multiphase mixed methods study protocol to develop a cross-cultural patient-reported outcome and experience measure for hand conditions (HAND-Q).  9:e025822-e025822. 2019
• Patient trade-offs between continuity and access in primary care interprofessional teaching clinics in Canada: a cross-sectional survey using discrete choice experiment.  9:e023578-e023578. 2019
• The ART of conversation: feasibility and acceptability of a pilot peer intervention to help transition complex HIV-positive people from hospital to community.  9:e026674-e026674. 2019
• Tramadol and the risk of seizure: nested case-control study of US patients with employer-sponsored health benefits.  9:e026705-e026705. 2019
• Adiposity measures and their validity in estimating risk of hypertension in South Asian children: a cross-sectional study.  9:e024087-e024087. 2019
• Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: a population-based clustered multiple baseline time series design.  9:e022984-e022984. 2019
• Examination of psychological risk factors for chronic pain following cardiac surgery: protocol for a prospective observational study.  9:e022995-e022995. 2019
• Minimal important differences for improvement in shoulder condition patient-reported outcomes: a systematic review to inform aBMJRapid Recommendation.  9:e028777-e028777. 2019
• Multimorbidity, eHealth and implications for equity: a cross-sectional survey of patient perspectives on eHealth.  9:e023731-e023731. 2019
• Quality of reporting of outcomes in trials of therapeutic interventions for pressure ulcers in adults: a protocol for a systematic survey.  9:e024633-e024633. 2019
• Shortening patient-reported outcome measures through optimal test assembly: application to the Social Appearance Anxiety Scale in the Scleroderma Patient-centered Intervention Network Cohort.  9:e024010-e024010. 2019
• Barriers to HIV care among Francophone African, Caribbean and Black immigrant people living with HIV in Canada: a protocol for a scoping systematic review.  9:e027440-e027440. 2019
• Effects of exercise interventions on cardiovascular health in individuals with chronic, motor complete spinal cord injury: protocol for a randomised controlled trial [Cardiovascular Health/Outcomes: Improvements Created by Exercise and education in SCI (CHOICES) Study].  9:e023540-e023540. 2019
• Health-related quality of life and anxiety in the PAN-CAN lung cancer screening cohort.  9:e024719-e024719. 2019
• Large care gaps in primary care management of asthma: a longitudinal practice audit.  9:e022506-e022506. 2019
• Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.  9:e023455-e023455. 2019
• Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol.  9:e024191-e024191. 2019
• Temporal trends in neonatal mortality and morbidity following spontaneous and clinician-initiated preterm birth in Washington State, USA: a population-based study.  9:e023004-e023004. 2019
• Feasibility and validity of the Health Status Classification System-Preschool (HSCS-PS) in a large community sample: the Generation R study.  8:e022449-e022449. 2018
• Identifying patient-important outcomes in medication-assisted treatment for opioid use disorder patients: a systematic review protocol.  8:e025059-e025059. 2018
• Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: an implementation and realist evaluation protocol.  8:e026433-e026433. 2018
• Evaluating comparative effectiveness of psychosocial interventions for persons receiving opioid agonist therapy for opioid use disorder: protocol for a systematic review..  8:e023902. 2018
• Acupuncture treatment for knee osteoarthritis with sensitive points: protocol for a multicentre randomised controlled trial.  8:e023838-e023838. 2018
• International phase I study protocol to develop a patient-reported outcome measure for adolescents and adults receiving gender-affirming treatments (the GENDER-Q).  8:e025435-e025435. 2018
• Effectiveness of service models and organisational structures supporting tuberculosis identification and management in hard-to-reach populations in countries of low and medium tuberculosis incidence: a systematic review..  8:e019642. 2018
• Strategies to improve adherence to antiretroviral therapy and retention in care for people living with HIV in high-income countries: a protocol for an overview of systematic reviews.  8:e022982-e022982. 2018
• Values and preferences of men for undergoing prostate-specific antigen screening for prostate cancer: a systematic review.  8:e025470-e025470. 2018
• Does perturbation-based balance training prevent falls among individuals with chronic stroke? A randomised controlled trial.  8:e021510-e021510. 2018
• FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial.  8:e022780-e022780. 2018
• Protocol for a scoping review about ethics in transition programmes for adolescents and young adults with neurodisabilities.  8:e020914-e020914. 2018
• Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data.  8:e025266-e025266. 2018
• Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire.  8:e021900-e021900. 2018
• Xylitol for the prevention of acute otitis media episodes in children aged 2–4 years: protocol for a pragmatic randomised controlled trial.  8:e020941-e020941. 2018
• Defining and measuring health equity effects in research on task shifting interventions in high-income countries: a systematic review protocol.  8:e021172-e021172. 2018
• Estimating the current and future cancer burden in Canada: methodological framework of the Canadian population attributable risk of cancer (ComPARe) study.  8:e022378-e022378. 2018
• Patent foramen ovale closure, antiplatelet therapy or anticoagulation in patients with patent foramen ovale and cryptogenic stroke: a systematic review and network meta-analysis incorporating complementary external evidence.  8:e023761-e023761. 2018
• Rationale and design for the detection and neurological impact of cerebrovascular events in non-cardiac surgery patients cohort evaluation (NeuroVISION) study: a prospective international cohort study.  8:e021521-e021521. 2018
• Comparative safety of bowel cleansers: protocol for a systematic review and network meta-analysis..  8:e021892. 2018
• Overweight and obesity management strategies in survivors of paediatric acute lymphoblastic leukaemia: a systematic review protocol.  8:e022530-e022530. 2018
• POP-Brazil study protocol: a nationwide cross-sectional evaluation of the prevalence and genotype distribution of human papillomavirus (HPV) in Brazil.  8:e021170-e021170. 2018
• Satisfactory Analgesia with Minimal Emesis in Day Surgeries (SAME DayS): a protocol for a randomised controlled trial of morphine versus hydromorphone.  8:e022504-e022504. 2018
• Establishing a protocol for building a pan-Canadian population-based monitoring system for early childhood development for children with health disorders: Canadian Children’s Health in Context Study (CCHICS).  8:e023688-e023688. 2018
• Multimorbidity in children and youth: a scoping review protocol.  8:e022413-e022413. 2018
• A protocol for a Canadian prospective observational study of decision-making on active surveillance or surgery for low-risk papillary thyroid cancer.  8:e020298-e020298. 2018
• Access to palliative care by disease trajectory: a population-based cohort of Ontario decedents.  8:e021147-e021147. 2018
• Identification and initial response to children’s exposure to intimate partner violence: a qualitative synthesis of the perspectives of children, mothers and professionals.  8:e019761-e019761. 2018
• Intermittent versus continuous oxygen saturation monitoring for infants hospitalised with bronchiolitis: study protocol for a pragmatic randomised controlled trial.  8:e022707-e022707. 2018
• Pathways of association between maternal haemoglobin and stillbirth: path-analysis of maternity data from two hospitals in England.  8:e020149-e020149. 2018
• Patient preferences for nutritional supplementation to improve fracture healing: a discrete choice experiment.  8:e019685-e019685. 2018
• Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial.  8:e020741-e020741. 2018
• Qualitative longitudinal study of episodic disability experiences of older women living with HIV in Ontario, Canada.  8:e021507-e021507. 2018
• Study protocol to assess the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units: a cluster-randomised, crossover trial (The ICU Visits Study).  8:e021193-e021193. 2018
• Use of the nominal group technique to identify stakeholder priorities and inform survey development: an example with informal caregivers of people with scleroderma..  8:e019726. 2018
• Effectiveness of implementation interventions in improving physician adherence to guideline recommendations in heart failure: a systematic review.  8:e017765-e017765. 2018
• Factor structure and convergent validity of the Derriford Appearance Scale-24 using standard scoring versus treating ‘not applicable’ responses as missing data: a Scleroderma Patient-centered Intervention Network (SPIN) cohort study.  8:e018641-e018641. 2018
• Self-management interventions for adults with chronic kidney disease: a scoping review.  8:e019814-e019814. 2018
• Study protocol for Vitality: a proof-of-concept randomised controlled trial of exercise training or complex mental and social activities to promote cognition in adults with chronic stroke.  8:e021490-e021490. 2018
• Temporal trends in severe maternal and neonatal trauma during childbirth: a population-based observational study.  8:e020578-e020578. 2018
• Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis.  8:e020991-e020991. 2018
• Protocol for a prospective, school-based standardisation study of a digital social skills assessment tool for children: The Paediatric Evaluation of Emotions, Relationships, and Socialisation (PEERS) study.  8:e016633-e016633. 2018
• Towards high-quality, useful practice guidelines for child and youth mental health disorders: protocol for a systematic review and consensus exercise.  8:e018053-e018053. 2018
• Healthy Foundations Study: a randomised controlled trial to evaluate biological embedding of early-life experiences.  8:e018915-e018915. 2018
• Knowledge, opinions and compliance related to the 100% smoke-free law in hospitality venues in Kampala, Uganda: cross-sectional results from theKOMPLY Project.  8:e017601-e017601. 2018
• Mental disorder in children with physical conditions: a pilot study.  8:e019011-e019011. 2018
• Two alternatives versus the standard Grading of Recommendations Assessment, Development and Evaluation (GRADE) summary of findings (SoF) tables to improve understanding in the presentation of systematic review results: a three-arm, randomised, controlled, non-inferiority trial.  8:e015623-e015623. 2018
• Understanding frailty: a qualitative study of European healthcare policy-makers’ approaches to frailty screening and management.  8:e018653-e018653. 2018
• Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.  7:e019022-e019022. 2017
• Comparing the diagnostic accuracy of five common tumour biomarkers and CA19-9 for pancreatic cancer: a protocol for a network meta-analysis of diagnostic test accuracy.  7:e018175-e018175. 2017
• Identifying and understanding the health and social care needs of older adults with multiple chronic conditions and their caregivers: a protocol for a scoping review.  7:e018247-e018247. 2017
• Improved risk stratification of patients with atrial fibrillation: an integrated GARFIELD-AF tool for the prediction of mortality, stroke and bleed in patients with and without anticoagulation.  7:e017157-e017157. 2017
• Investigating the effect of sociodemographic factors on 30-day hospital readmission among medical patients in Toronto, Canada: a prospective cohort study.  7:e017956-e017956. 2017
• Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students.  7:e019365-e019365. 2017
• Senior high-cost healthcare users’ resource utilization and outcomes: a protocol of a retrospective matched cohort study in Canada.  7:e018488-e018488. 2017
• Values and preferences of women living with HIV who are pregnant, postpartum or considering pregnancy on choice of antiretroviral therapy during pregnancy.  7:e019023-e019023. 2017
• Does the impact of a plant-based diet during pregnancy on birth weight differ by ethnicity? A dietary pattern analysis from a prospective Canadian birth cohort alliance.  7:e017753-e017753. 2017
• Early vasopressor use following traumatic injury: a systematic review.  7:e017559-e017559. 2017
• Self-management of cardiac pain in women: an evidence map.  7:e018549-e018549. 2017
• UpToDate adherence to GRADE criteria for strong recommendations: an analytical survey.  7:e018593-e018593. 2017
• Association between statistical significance and time to publication among systematic reviews: a study protocol for a meta-epidemiological investigation.  7:e018856-e018856. 2017
• Better early functional outcome after short stem total hip arthroplasty? A prospective blinded randomised controlled multicentre trial comparing the Collum Femoris Preserving stem with a Zweymuller straight cementless stem total hip replacement for the treatment of primary osteoarthritis of the hip.  7:e014522-e014522. 2017
• Effectiveness and meaningful use of paediatric surgical safety checklists and their implementation strategies: a systematic review with narrative synthesis.  7:e016298-e016298. 2017
• Implementation and impact of an online tool used in primary care to improve access to financial benefits for patients: a study protocol.  7:e015947-e015947. 2017
• Mandated reporters’ experiences with reporting child maltreatment: a meta-synthesis of qualitative studies.  7:e013942-e013942. 2017
• Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors.  7:e018858-e018858. 2017
• Correction: Medication incidents in primary care medicine: a prospective study in the Swiss Sentinel Surveillance Network (Sentinella).  7:e013658corr1-e013658corr1. 2017
• Development and validation of the Fracture Risk Scale (FRS) that predicts fracture over a 1-year time period in institutionalised frail older people living in Canada: an electronic record-linked longitudinal cohort study.  7:e016477-e016477. 2017
• Long-term risk of recurrence after discontinuing anticoagulants for a first unprovoked venous thromboembolism: protocol for a systematic review and meta-analysis.  7:016950-016950. 2017
• Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews.  7:e017138-e017138. 2017
• The role of pragmatism in explaining heterogeneity in meta-analyses of randomised trials: a protocol for a cross-sectional methodological review.  7:e017887-e017887. 2017
• When is a randomised controlled trial health equity relevant? Development and validation of a conceptual framework.  7:e015815-e015815. 2017
• A national surveillance project on chronic kidney disease management in Canadian primary care: a study protocol.  7:e016267-e016267. 2017
• Answering medical questions at the point of care: a cross-sectional study comparing rapid decisions based on PubMed and Epistemonikos searches with evidence-based recommendations developed with the GRADE approach.  7:e016113-e016113. 2017
• Comparison of health-related quality of life in patients with atrial fibrillation treated with catheter ablation or antiarrhythmic drug therapy: a systematic review and meta-analysis protocol.  7:e017577-e017577. 2017
• Does the person’s context influence engagement in life activities following primary knee replacement? Results from a Canadian prospective cohort study.  7:e015737-e015737. 2017
• Long-term outcomes after acute myocardial infarction in countries with different socioeconomic environments: an international prospective cohort study.  7:e012715-e012715. 2017
• Optic nerve sheath diameter sonography for the diagnosis of increased intracranial pressure: a systematic review and meta-analysis protocol.  7:e016194-e016194. 2017
• Predictors of discharge destination from acute care in patients with traumatic brain injury.  7:e016694-e016694. 2017
• Protocol for a randomised, placebo-controlled pilot study for assessing feasibility and efficacy of faecal microbiota transplantation in a paediatric ulcerative colitis population: PediFETCh trial.  7:e016698-e016698. 2017
• The provision of medical assistance in dying: protocol for a scoping review.  7:e017888-e017888. 2017
• Advancing Concussion Assessment in Pediatrics (A-CAP): a prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: study protocol.  7:e017012-e017012. 2017
• Discontinuation and non-publication of randomised clinical trials supported by the main public funding body in Switzerland: a retrospective cohort study.  7:e016216-e016216. 2017
• Fluids in Sepsis and Septic Shock (FISSH): protocol for a pilot randomised controlled trial.  7:e017602-e017602. 2017
• Guideline recommendations and antimicrobial resistance: the need for a change.  7:e016264-e016264. 2017
• Herbal medications for surgical patients: a systematic review protocol.  7:e014290-e014290. 2017
• Prevalence and antibiotic resistance ofMycoplasma genitaliumamong STI clinic attendees in Western Canada: a cross-sectional analysis.  7:e016300-e016300. 2017
• Retrospective economic analysis of the transfer of services from hospitals to the community: an application to an enhanced eye care service.  7:e014089-e014089. 2017
• Assessing the diagnostic accuracy of PCR-based detection ofStreptococcus pneumoniaefrom nasopharyngeal swabs collected for viral studies in Canadian adults hospitalised with community-acquired pneumonia: a Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research (CIRN) study.  7:e015008-e015008. 2017
• Axillary versus innominate artery cannulation for antegrade cerebral perfusion in aortic surgery: design of the Aortic Surgery Cerebral Protection Evaluation (ACE) CardioLink-3 randomised trial.  7:e014491-e014491. 2017
• Corticosteroids in sepsis: an updated systematic review and meta-analysis (protocol).  7:e016847-e016847. 2017
• Defining clinically important perioperative blood loss and transfusion for the Standardised Endpoints for Perioperative Medicine (StEP) collaborative: a protocol for a scoping review.  7:e016743-e016743. 2017
• Effect of corticosteroid administration on neurologically deceased organ donors and transplant recipients: a systematic review and meta-analysis.  7:e014436-e014436. 2017
• Evaluation of a physiatrist-directed prehabilitation intervention in frail patients with colorectal cancer: a randomised pilot study protocol.  7:e015565-e015565. 2017
• Methods, applications, interpretations and challenges of interrupted time series (ITS) data: protocol for a scoping review.  7:e016018-e016018. 2017
• Promoting Optimal Physical Exercise for Life (PROPEL): aerobic exercise and self-management early after stroke to increase daily physical activity—study protocol for a stepped-wedge randomised trial.  7:e015843-e015843. 2017
• The Bipolar Illness Onset study: research protocol for the BIO cohort study.  7:e015462-e015462. 2017
• Thinker, Soldier, Scribe: cross-sectional study of researchers' roles and author order in theAnnals of Internal Medicine.  7:e013898-e013898. 2017
• A cross-sectional study measuring vanadium and chromium levels in paediatric patients with CKD.  7:e014821-e014821. 2017
• Application of minimal important differences in degenerative knee disease outcomes: a systematic review and case study to informBMJRapid Recommendations.  7:e015587-e015587. 2017
• Knee arthroscopy versus conservative management in patients with degenerative knee disease: a systematic review.  7:e016114-e016114. 2017
• Randomised trial of mitral valve repair with leaflet resection versus leaflet preservation on functional mitral stenosis (The CAMRA CardioLink-2 Trial).  7:e015032-e015032. 2017
• Deprescribing anticholinergic and sedative medicines: protocol for a Feasibility Trial (DEFEAT-polypharmacy) in residential aged care facilities.  7:e013800-e013800. 2017
• Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study.  7:e013779-e013779. 2017
• Quality of reporting in abstracts of RCTs published in emergency medicine journals: a protocol for a systematic survey of the literature.  7:e014981-e014981. 2017
• Atraumatic versus traumatic lumbar puncture needles: a systematic review and meta-analysis protocol.  7:e014478-e014478. 2017
• Cross-sectional associations between dietary intake and carotid intima media thickness in type 2 diabetes: baseline data from a randomised trial.  7:e015026-e015026. 2017
• Impact of gender on event rates at 1 year in patients with newly diagnosed non-valvular atrial fibrillation: contemporary perspective from the GARFIELD-AF registry.  7:e014579-e014579. 2017
• Improving prescribing practices with rapid diagnostic tests (RDTs): synthesis of 10 studies to explore reasons for variation in malaria RDT uptake and adherence.  7:e012973-e012973. 2017
• State of reporting of primary biomedical research: a scoping review protocol.  7:e014749-e014749. 2017
• Integrated collaborative care teams to enhance service delivery to youth with mental health and substance use challenges: protocol for a pragmatic randomised controlled trial.  7:e014080-e014080. 2017
• Vasopressor use following traumatic injury: protocol for a systematic review.  7:e014166-e014166. 2017
• Awareness and attitudes of the Lebanese population with regard to physician–pharmaceutical company interaction: a survey study.  7:e013041-e013041. 2017
• Characteristics of funding of clinical trials: cross-sectional survey and proposed guidance.  7:e015997-e015997. 2017
• Electronic nicotine delivery systems and/or electronic non-nicotine delivery systems for tobacco smoking cessation or reduction: a systematic review and meta-analysis.  7:e012680-e012680. 2017
• External validation of the Revised Cardiac Risk Index and update of its renal variable to predict 30-day risk of major cardiac complications after non-cardiac surgery: rationale and plan for analyses of the VISION study.  7:e013510-e013510. 2017
• International multiphase mixed methods study protocol to develop a cross-cultural patient-reported outcome instrument for children and young adults with cleft lip and/or palate (CLEFT-Q).  7:e015467-e015467. 2017
• Multilayered and digitally structured presentation formats of trustworthy recommendations: a combined survey and randomised trial.  7:e011569-e011569. 2017
• Obstetrical brachial plexus injury (OBPI): Canada's national clinical practice guideline.  7:e014141-e014141. 2017
• Prevention and assessment of infectious diseases among children and adult migrants arriving to the European Union/European Economic Association: A protocol for a suite of systematic reviews for public health and health systems.  7:e014608-e014608. 2017
• Algorithm for predicting death among older adults in the home care setting: study protocol for the Risk Evaluation for Support: Predictions for Elder-life in the Community Tool (RESPECT).  6:e013666-e013666. 2016
• Aneurysmal SubArachnoid Hemorrhage—Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol.  6:e012623-e012623. 2016
• Development of a brief measure of intimate partner violence experiences: the Composite Abuse Scale (Revised)—Short Form (CAS_R-SF).  6:e012824-e012824. 2016
• Process mapping evaluation of medication reconciliation in academic teaching hospitals: a critical step in quality improvement.  6:e013663-e013663. 2016
• Reporting quality in abstracts of meta-analyses of depression screening tool accuracy: a review of systematic reviews and meta-analyses..  6:e012867. 2016
• Comparative effectiveness and safety of oral anticoagulants for atrial fibrillation in real-world practice: a population-based cohort study protocol.  6:e013263-e013263. 2016
• Framing of research question using the PICOT format in randomised controlled trials of venous ulcer disease: a protocol for a systematic survey of the literature.  6:e013175-e013175. 2016
• Gabapentinoids for chronic low back pain: a protocol for systematic review and meta-analysis of randomised controlled trials.  6:e013200-e013200. 2016
• Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis.  6:e014390-e014390. 2016
• Predictors of in-hospital mortality among patients with pulmonary tuberculosis: a protocol of systematic review and meta-analysis of observational studies.  6:e011957-e011957. 2016
• Preference-based disease-specific health-related quality of life instrument for glaucoma: a mixed methods study protocol.  6:e012732-e012732. 2016
• Prevalence of papillomavirus in Brazil: a systematic review protocol.  6:e011884-e011884. 2016
• Reporting quality of abstracts of trials published in top five pain journals: a protocol for a systematic survey.  6:e012319-e012319. 2016
• Surgical ablation of atrial fibrillation: a protocol for a systematic review and meta-analysis of randomised controlled trials.  6:e013273-e013273. 2016
• Towards the genetic basis of cerebral venous thrombosis—the BEAST Consortium: a study protocol.  6:e012351-e012351. 2016
• Evaluating a community-based exercise intervention with adults living with HIV: protocol for an interrupted time series study.  6:e013618-e013618. 2016
• Fructose intake and risk of gout and hyperuricemia: a systematic review and meta-analysis of prospective cohort studies.  6:e013191-e013191. 2016
• Association between progression-free survival and health-related quality of life in oncology: a systematic review protocol.  6:e012909-e012909. 2016
• Exploring the experiences of substitute decision-makers with an exception to consent in a paediatric resuscitation randomised controlled trial: study protocol for a qualitative research study.  6:e012931-e012931. 2016
• Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS.  6:e011148-e011148. 2016
• Patient values and preferences on transcatheter or surgical aortic valve replacement therapy for aortic stenosis: a systematic review.  6:e014327-e014327. 2016
• Predictors of physical functioning after total hip arthroplasty: a systematic review.  6:e010725-e010725. 2016
• Strategies and impacts of patient and family engagement in collaborative mental healthcare: protocol for a systematic and realist review.  6:e012949-e012949. 2016
• Comparative study analysing women's childbirth satisfaction and obstetric outcomes across two different models of maternity care.  6:e011362-e011362. 2016
• False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review.  6:e011890-e011890. 2016
• Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study.  6:e010983-e010983. 2016
• Effectiveness and safety of treatments used for the management of patent ductus arteriosus (PDA) in preterm infants: a protocol for a systematic review and network meta-analysis.  6:e011271-e011271. 2016
• Identifying process and outcome indicators of successful transitions from child to adult mental health services: protocol for a scoping review.  6:e012376-e012376. 2016
• Low-glycaemic index diet to improve glycaemic control and cardiovascular disease in type 2 diabetes: design and methods for a randomised, controlled, clinical trial.  6:e012220-e012220. 2016
• Multicountry survey of emergency and critical care medicine physicians’ fluid resuscitation practices for adult patients with early septic shock.  6:e010041-e010041. 2016
• Simulation study to determine the impact of different design features on design efficiency in discrete choice experiments.  6:e011985-e011985. 2016
• Understanding the role of the immune system in adolescent idiopathic scoliosis: Immunometabolic CONnections to Scoliosis (ICONS) study protocol.  6:e011812-e011812. 2016
• Correction:How do women trade-off benefits and risks in chemotherapy treatment decisions based on gene expression profiling for early-stage breast cancer? A discrete choice experiment.  6:e010981corr1-e010981corr1. 2016
• Empirical evaluation of the Q-Genie tool: a protocol for assessment of effectiveness.  6:e010403-e010403. 2016
• How do women trade-off benefits and risks in chemotherapy treatment decisions based on gene expression profiling for early-stage breast cancer? A discrete choice experiment.  6:e010981-e010981. 2016
• Making patient values visible in healthcare: a systematic review of tools to assess patient treatment priorities and preferences in the context of multimorbidity.  6:e010903-e010903. 2016
• Measuring engagement in advance care planning: a cross-sectional multicentre feasibility study.  6:e010375-e010375. 2016
• Reporting of planned statistical methods in published surgical randomised trial protocols: a protocol for a methodological systematic review.  6:e011188-e011188. 2016
• Sexual counselling for patients with cardiovascular disease: protocol for a pilot study of the CHARMS sexual counselling intervention.  6:e011219-e011219. 2016
• β-Blockers in sepsis: protocol for a systematic review and meta-analysis of randomised control trials.  6:e012466-e012466. 2016
• Factors influencing communication and decision-making about life-sustaining technology during serious illness: a qualitative study.  6:e010451-e010451. 2016
• Intrathecal hyperbaric versus isobaric bupivacaine for adult non-caesarean-section surgery: systematic review protocol.  6:e010885-e010885. 2016
• Moving forward through consensus: protocol for a modified Delphi approach to determine the top research priorities in the field of orthopaedic oncology.  6:e011780-e011780. 2016
• Treatment goal setting for complex patients: protocol for a scoping review.  6:e011869-e011869. 2016
• Biologic Treatment Registry Across Canada (BioTRAC): a multicentre, prospective, observational study of patients treated with infliximab for ankylosing spondylitis.  6:e009661-e009661. 2016
• CYCLE pilot: a protocol for a pilot randomised study of early cycle ergometry versus routine physiotherapy in mechanically ventilated patients.  6:e011659-e011659. 2016
• Cigarette smoking in a Middle Eastern country and its association with hospitalisation use: a nationwide cross-sectional study.  6:e009881-e009881. 2016
• Examining the social determinants of children's developmental health: protocol for building a pan-Canadian population-based monitoring system for early childhood development.  6:e012020-e012020. 2016
• Curved versusStraight Stem UncementedTotal Hip ArthroplastyOsteoarthritisMulticenter trial (CUSTOM): design of a prospective blinded randomised controlled multicentre trial.  6:e010472-e010472. 2016
• Are you ready? Exploring readiness to engage in exercise among people living with HIV and multimorbidity in Toronto, Canada: a qualitative study.  6:e010029-e010029. 2016
• Effect of serotonin modulating pharmacotherapies on body mass index and dysglycaemia among children and adolescents: a systematic review and network meta-analysis protocol.  6:e009998-e009998. 2016
• Effectiveness of implementation strategies in improving physician adherence to guideline recommendations in heart failure: a systematic review protocol.  6:e009364-e009364. 2016
• Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a protocol for a scoping review of the literature and international policies.  6:e010959-e010959. 2016
• Resident reflections on end-of-life education: a mixed-methods study of the 3 Wishes Project.  6:e010626-e010626. 2016
• Does preoperative rehabilitation for patients planning to undergo joint replacement surgery improve outcomes? A systematic review and meta-analysis of randomised controlled trials.  6:e009857-e009857. 2016
• Effect of obesity on cognition in adults with and without a mood disorder: study design and methods.  6:e009347-e009347. 2016
• A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial.  6:e010156-e010156. 2016
• Bias in dissemination of clinical research findings: structured OPEN framework of what, who and why, based on literature review and expert consensus.  6:e010024-e010024. 2016
• Impact of point-of-care diagnostics on maternal outcomes in HIV-infected women: systematic review and meta-analysis protocol.  6:e008002-e008002. 2016
• Reporting of financial and non-financial conflicts of interest by authors of systematic reviews: a methodological survey.  6:e011997-e011997. 2016
• Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol.  6:e010569-e010569. 2016
• Using a Delphi process to define priorities for prison health research in Canada.  6:e010125-e010125. 2016
• Effect of increased water intake on plasma copeptin in patients with chronic kidney disease: results from a pilot randomised controlled trial.  5:e008634-e008634. 2015
• Prediction of individual combined benefit and harm for patients with atrial fibrillation considering warfarin therapy: a study protocol.  5:e009518-e009518. 2015
• Minimally important difference estimates and methods: a protocol.  5:e007953-e007953. 2015
• A protocol for developing early warning score models from vital signs data in hospitals using ensembles of decision trees.  5:e008699-e008699. 2015
• Capturing the experiences of patients across multiple complex interventions: a meta-qualitative approach.  5:e007664-e007664. 2015
• Association of worker characteristics and early reimbursement for physical therapy, chiropractic and opioid prescriptions with workers’ compensation claim duration, for cases of acute low back pain: an observational cohort study.  5:e007836-e007836. 2015
• Management of persistent postconcussion symptoms in youth: a randomised control trial protocol.  5:e008468-e008468. 2015
• Cost-effectiveness of nurse practitioners in primary and specialised ambulatory care: systematic review.  5:e007167-e007167. 2015
• Hyperbaric Oxygen in Lower Limb Trauma (HOLLT); protocol for a randomised controlled trial.  5:e008381-e008381. 2015
• Rationale and methods of a multicentre randomised controlled trial of the effectiveness of a Community Health Assessment Programme with Emergency Medical Services (CHAP-EMS) implemented on residents aged 55 years and older in subsidised seniors’ housing buildings in Ontario, Canada.  5:e008110-e008110. 2015
• Scoping review of physical rehabilitation interventions in long-term care: protocol for tools, models of delivery, outcomes and quality indicators.  5:e007528-e007528. 2015
• Video decision aids to assist with advance care planning: a systematic review and meta-analysis.  5:e007491-e007491. 2015
• What matters most for end-of-life care? Perspectives from community-based palliative care providers and administrators.  5:e007492-e007492. 2015
• Are two youth-focused interventions sufficient to empower youth with chronic health conditions in their transition to adult healthcare: a mixed-methods longitudinal prospective cohort study.  5:e007553-e007553. 2015
• Efficacy of temporary work modifications on disability related to musculoskeletal pain or depressive symptoms—study protocol for a controlled trial.  5:e008300-e008300. 2015
• Evidence-informed recommendations to reduce dissemination bias in clinical research: conclusions from the OPEN (Overcome failure to Publish nEgative fiNdings) project based on an international consensus meeting.  5:e006666-e006666. 2015
• Effects of electroconvulsive therapy on cognitive functioning in patients with depression: protocol for a systematic review and meta-analysis.  5:e006966-e006966. 2015
• Effectiveness of knowledge translation tools addressing multiple high-burden chronic diseases affecting older adults: protocol for a systematic review alongside a realist review.  5:e007640-e007640. 2015
• Hip fracture evaluation with alternatives of total hip arthroplasty versus hemiarthroplasty (HEALTH): protocol for a multicentre randomised trial.  5:e006263-e006263. 2015
• The effect of Chinese herbal medicine Jian Ling Decoction for the treatment of essential hypertension: a systematic review.  5:e006502-e006502. 2015
• Body composition and bone health in long-term survivors of acute lymphoblastic leukaemia in childhood and adolescence: the protocol for a cross-sectional cohort study.  5:e006191-e006191. 2015
• Chinese herbal medicine for resistant hypertension: a systematic review.  5:e005355-e005355. 2015
• Correlates of former smoking in patients with cerebrovascular disease: a cross-sectional study.  5:e005753-e005753. 2015
• Interventions to combat or prevent drug counterfeiting: a systematic review.  5:e006290-e006290. 2015
• Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide.  5:e008431-e008431. 2015
• Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.  5:e009368-e009368. 2015
• The African, Caribbean and European (ACE) Pathways to Care study: a qualitative exploration of similarities and differences between African-origin, Caribbean-origin and European-origin groups in pathways to care for psychosis.  5:e006562-e006562. 2015
• Increasing proportion of female patients with ankylosing spondylitis: a population-based study of trends in the incidence and prevalence of AS.  4:e006634-e006634. 2014
• Classification of osteoarthritis phenotypes by metabolomics analysis.  4:e006286-e006286. 2014
• Management of chronic neuropathic pain: a protocol for a multiple treatment comparison meta-analysis of randomised controlled trials.  4:e006112-e006112. 2014
• Patients’ values and preferences of the expected efficacy of hip arthroscopy for osteoarthritis: a protocol for a multinational structured interview-based study combined with a randomised survey on the optimal amount of information to elicit preferences.  4:e005536-e005536. 2014
• Treatment crossovers in time-to-event non-inferiority randomised trials of radiotherapy in patients with breast cancer.  4:e006531-e006531. 2014
• ‘Conditional candour’ and ‘knowing me’: an interpretive description study on patient preferences for physician behaviours during end-of-life communication.  4:e005653-e005653. 2014
• Interpreting trial results following use of different intention-to-treat approaches for preventing attrition bias: a meta-epidemiological study protocol.  4:e005297-e005297. 2014
• Measuring disability experienced by adults living with HIV: assessing construct validity of the HIV Disability Questionnaire using confirmatory factor analysis.  4:e005456-e005456. 2014
• Brazilian medicinal plants to treat upper respiratory tract and bronchial illness: systematic review and meta-analyses—study protocol.  4:e005267-e005267. 2014
• Effect of tree nuts on metabolic syndrome criteria: a systematic review and meta-analysis of randomised controlled trials.  4:e004660-e004660. 2014
• Extended-release nifedipine and the risk of intestinal obstruction: a population-based study.  4:e005377-e005377. 2014
• Perceptions of chronically ill and healthy consumers about electronic personal health records: a comparative empirical investigation.  4:e005304-e005304. 2014
• Rapid paediatric fluid resuscitation: a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques in a simulated setting.  4:e005028-e005028. 2014
• Correction.  4:e005123corr1-e005123corr1. 2014
• Estimating treatment effects in randomised controlled trials with non-compliance: a simulation study.  4:e005362-e005362. 2014
• Outcomes after corrective surgery for congenital dextro-transposition of the great arteries using the arterial switch technique: a protocol for a scoping systematic review.  4:e005123-e005123. 2014
• Recruitment feasibility to a cohort study of endocrine and metabolic health among survivors of childhood brain tumours: a report from the Canadian study of Determinants of Endometabolic Health in ChIlDrEn (CanDECIDE).  4:e005295-e005295. 2014
• Evidence-informed recommendations for rehabilitation with older adults living with HIV: a knowledge synthesis.  4:e004692-e004692. 2014
• The clinical relevance and newsworthiness of NIHR HTA-funded research: a cohort study.  4:e004556-e004556. 2014
• Effect of green tea supplementation on blood pressure among overweight and obese adults: a protocol for a systematic review.  4:e004971-e004971. 2014
• The effect of weekly text-message communication on treatment completion among patients with latent tuberculosis infection: study protocol for a randomised controlled trial (WelTel LTBI).  4:e004362-e004362. 2014
• Adherence to guidelines in the use of biological agents to treat psoriasis in Brazil.  4:e004179-e004179. 2014
• Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial.  4:e004842-e004842. 2014
• Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale.  4:e004282-e004282. 2014
• Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial.  4:e004886-e004886. 2014
• Access to rheumatologists among patients with newly diagnosed rheumatoid arthritis in a Canadian universal public healthcare system.  4:e003888-e003888. 2014
• Legislative, educational, policy and other interventions targeting physicians’ interaction with pharmaceutical companies: a systematic review.  4:e004880-e004880. 2014
• Shorter or longer anticoagulation to prevent recurrent venous thromboembolism: systematic review and meta-analysis.  4:e005674-e005674. 2014
• Mobile phone text messages for improving adherence to antiretroviral therapy (ART): an individual patient data meta-analysis of randomised trials.  3:e003950-e003950. 2013
• The chronic kidney disease Water Intake Trial (WIT): results from the pilot randomised controlled trial.  3:e003666-e003666. 2013
• The comparative risk of new-onset diabetes after prescription of drugs for cardiovascular risk prevention in primary care: a national cohort study.  3:e003475-e003475. 2013
• A generalised model for individualising a treatment recommendation based on group-level evidence from randomised clinical trials.  3:e003143-e003143. 2013
• Comparing two types of macrolide antibiotics for the purpose of assessing population-based drug interactions.  3:e002857-e002857. 2013
• Effects of centrally acting ACE inhibitors on the rate of cognitive decline in dementia.  3:e002881-e002881. 2013
• Predicting and preventing postconcussive problems in paediatrics (5P) study: protocol for a prospective multicentre clinical prediction rule derivation study in children with concussion.  3:e003550-e003550. 2013
• Canadian Study of Determinants of Endometabolic Health in ChIlDrEn (CanDECIDE study): a cohort study protocol examining the mechanisms of obesity in survivors of childhood brain tumours.  3:e002869-e002869. 2013
• Investigating community ownership of a text message programme to improve adherence to antiretroviral therapy and provider-client communication: a mixed methods research protocol.  3:e002816-e002816. 2013
• The effect of weekly short message service communication on patient retention in care in the first year after HIV diagnosis: study protocol for a randomised controlled trial (WelTel Retain).  3:e003155-e003155. 2013
• An observational study of the hand hygiene initiative: a comparison of preintervention and postintervention outcomes.  3:e003018-e003018. 2013
• Case–control and prospective studies of dietary α-linolenic acid intake and prostate cancer risk: a meta-analysis.  3:e002280-e002280. 2013
• Development and validation of a brief screening instrument for psychosocial risk associated with genetic testing: a pan-Canadian cohort study.  3:e002227-e002227. 2013
• Framework of policy recommendations for implementation of evidence-based practice: a systematic scoping review.  3:e001881-e001881. 2013
• Identifying geographical regions serviced by hospitals to assess laboratory-based outcomes.  3:e001921-e001921. 2013
• Mobile phone text messages for improving adherence to antiretroviral therapy (ART): a protocol for an individual patient data meta-analysis of randomised trials.  3:e002954-e002954. 2013
• Study protocol for a randomised controlled trial comparing the efficiency of two provider-endorsed manual paediatric fluid resuscitation techniques.  3:e002754-e002754. 2013
• Sustainability of knowledge translation interventions in healthcare decision-making: protocol for a scoping review.  3:e002970-e002970. 2013
• The relationship between osteoarthritis and cardiovascular disease in a population health survey: a cross-sectional study.  3:e002624-e002624. 2013
• A retrospective cross-sectional study of risk factors and clinical spectrum of children admitted to hospital with pandemic H1N1 influenza as compared to influenza A.  2:e000310-e000310. 2012
• Coronary Artery Bypass Grafting Surgery Off- or On-pump Revascularisation Study (CORONARY): kidney substudy analytic protocol of an international randomised controlled trial.  2:e001080-e001080. 2012
• Inter-rater and test–retest reliability of quality assessments by novice student raters using the Jadad and Newcastle–Ottawa Scales.  2:e001368-e001368. 2012
• Jurisdictional, socioeconomic and gender inequalities in child health and development: analysis of a national census of 5-year-olds in Australia.  2:e001075-e001075. 2012
• Prophylactic antibiotic regimens in tumour surgery (PARITY): protocol for a multicentre randomised controlled study.  2:e002197-e002197. 2012
• Psychometric properties of a questionnaire to assess exercise-related musculoskeletal injuries in older adults attending a community-based fitness facility.  2:e001777-e001777. 2012
• The coronary CT angiography vision protocol: a prospective observational imaging cohort study in patients undergoing non-cardiac surgery.  2:e001474-e001474. 2012
• The effectiveness of smoking cessation interventions in smokers with cerebrovascular disease: a systematic review.  2:e002022-e002022. 2012
• Validity of theInternational Classification of Diseases 10th revisioncode for hospitalisation with hyponatraemia in elderly patients.  2:e001727-e001727. 2012
• Validity of theInternational Classification of Diseases 10th revisioncode for hyperkalaemia in elderly patients at presentation to an emergency department and at hospital admission.  2:e002011-e002011. 2012
• Validity of theInternational Classification of Diseases, Tenth Revisioncode for acute kidney injury in elderly patients at presentation to the emergency department and at hospital admission.  2:e001821-e001821. 2012
• What is a disease? Perspectives of the public, health professionals and legislators.  2:e001632-e001632. 2012
• A randomised controlled pilot study of standardised counselling and cost-free pharmacotherapy for smoking cessation among stroke and TIA patients.  1:e000366-e000366. 2011
• The At Home/Chez Soi trial protocol: a pragmatic, multi-site, randomised controlled trial of a Housing First intervention for homeless individuals with mental illness in five Canadian cities.  1:e000323-e000323. 2011
• The quality of websites addressing fibromyalgia: an assessment of quality and readability using standardised tools.  1:e000152-e000152. 2011

has subject area

• 1103 Clinical Sciences (FoR)
• 1117 Public Health and Health Services (FoR)
• 1199 Other Medical and Health Sciences (FoR)

Identity

International Standard Serial Number (ISSN)

• 0008-6312
• 2044-6055

Electronic International Standard Serial Number (EISSN)

• 1421-9751
• 2044-6055