Biological Products Concept

subject area of

• 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis  Academic Article
• 2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis  Academic Article
• 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty  Academic Article
• 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis  Academic Article
• 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis  Academic Article
• A Psoriatic Patient-Based Survey on the Understanding of the Use of Vaccines While on Biologics During the COVID-19 Pandemic  Academic Article
• A Review of Drug-Drug Interactions for Biologic Drugs Used in the Treatment of Psoriasis  Academic Article
• A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent  Academic Article
• A Useful Clinical Tool for Psoriasis  Academic Article
• A brief guide to machine learning for antibiotic discovery  Academic Article
• A case series of dual biologics therapy for severe asthma  Academic Article
• A macrophage-stimulating compound from a screen of microbial natural products  Academic Article
• A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity  Academic Article
• A simple bioassay for monocyte-derived hepatocyte stimulating factor: Increased synthesis of α2-macroglobulin and reduced synthesis of albumin by cultured rat hepatocytes  Academic Article
• A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines  Academic Article
• A z2 laterally-fed membrane chromatography device for fast high-resolution purification of biopharmaceuticals  Academic Article
• AR101 Oral Immunotherapy for Peanut Allergy  Academic Article
• Accessorizing natural products: Adding to nature's toolbox  Academic Article
• Adjuvant Chemotherapy With or Without Biologics Including Antiangiogenics and Monoclonal Antibodies Targeting EGFR and EpCAM in Colorectal Cancer: A Systematic Review and Meta-analysis  Academic Article
• Adverse effects of biologics: a network meta-analysis and Cochrane overview  Academic Article
• Alveolar Macrophage/Peripheral Blood Monocyte-Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts  Academic Article
• An Engineered Allele of afsQ1 Facilitates the Discovery and Investigation of Cryptic Natural Products  Academic Article
• An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products  Academic Article
• An ecological perspective of microbial secondary metabolism  Academic Article
• Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D–F  Academic Article
• Antibiotic Dereplication Using the Antibiotic Resistance Platform  Academic Article
• Antibiotics: A New Hope  Academic Article
• Appropriateness of Biologics in the Management of Crohn’s Disease Using RAND/UCLA Appropriateness Methodology  Academic Article
• Architectures, mechanisms and molecular evolution of natural product methyltransferases  Academic Article
• Are there differences between young- and older-onset early inflammatory arthritis and do these impact outcomes? An analysis from the CATCH cohort  Academic Article
• Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance  Academic Article
• Assembly and clustering of natural antibiotics guides target identification  Academic Article
• Association of Patient, Prescriber, and Region With the Initiation of First Prescription of Biologic Disease-Modifying Antirheumatic Drug Among Older Patients With Rheumatoid Arthritis and Identical Health Insurance Coverage  Academic Article
• Automated Identification of Depsipeptide Natural Products by an Informatic Search Algorithm  Academic Article
• BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics  Academic Article
• Back to the future: a new ‘old’ lead for tuberculosis  Academic Article
• Biologic survival.  Academic Article
• Biologic therapies and bone loss in rheumatoid arthritis  Academic Article
• Biological treatments for systemic lupus erythematosus  Academic Article
• Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma  Academic Article
• Biosynthesis of the Fluorinated Natural Product Nucleocidin inStreptomyces calvusIs Dependent on thebldA-Specified Leu-tRNA^UUAMolecule  Academic Article
• Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis  Academic Article
• Changes in Market Share of Biologic and Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs for Treatment of Rheumatoid Arthritis: Results from the Ontario Best-Practice Research Initiative Database  Academic Article
• Checklist for the Systemic Treatment of Psoriasis Using Biologics: A Delphi Study  Academic Article
• Chemical and biosynthetic evolution of the antimycin-type depsipeptides  Academic Article
• Christopher Walsh: Pioneer and innovator in antibiotic and natural product chemical biology  Book
• Comparative Effectiveness of Biologics for Endoscopic Healing of the Ileum and Colon in Crohn's Disease  Conference Paper
• Comparative Efficacy and Rapidity of Action for Infliximab vs Ustekinumab in Biologic Naïve Crohn’s Disease  Academic Article
• Comparative Efficacy for Infliximab Vs Vedolizumab in Biologic Naive Ulcerative Colitis  Academic Article
• Comparison of the acute phase response of cultured Morris hepatoma 7777 cells and of rat hepatocytes.  Academic Article
• Complete Response as an Intermediate End Point in Patients Receiving Salvage Systemic Therapy for Urothelial Carcinoma  Academic Article
• Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions  Academic Article
• Controversies Around Measuring Drug Toxicity: US Food and Drug Administration and Gastrointestinal Perspectives  Academic Article
• Controversies in Allergy: Aspirin Desensitization or Biologics for Aspirin-Exacerbated Respiratory Disease—How to Choose  Academic Article
• Cost-effectiveness analysis of secukinumab for the treatment of active psoriatic arthritis: a Canadian perspective  Academic Article
• Current use of biologicals in thrombosis and haemostasis  Academic Article
• Cytokines and other mediators in rheumatoid arthritis  Academic Article
• Dedication: Heinz Floss and Christopher Walsh—pioneers in natural product chemical biology  Academic Article
• DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products  Academic Article
• Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery  Academic Article
• Development of isoporous microslit silicon nitride membranes for sterile filtration applications  Academic Article
• Discovery of Ibomycin, a Complex Macrolactone that Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function  Academic Article
• Does the Addition of Biologic Agents to Chemotherapy in Patients with Unresectable Colorectal Cancer Metastases Result in a Higher Proportion of Patients Undergoing Resection? A Systematic Review and Meta-analysis  Academic Article
• Early Change in Epithelial Neutrophilic Infiltrate Predicts Long-Term Response to Biologics in Ulcerative Colitis  Academic Article
• Effect of Concomitant Disease-modifying Antirheumatic Drugs and Methotrexate Administration Route on Biologic Treatment Durability in Rheumatoid Arthritis: OBRI Cohort Results  Academic Article
• Effect of anti‐IL‐5 biologics on weight and body mass index  Academic Article
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma  Academic Article
• Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma  Academic Article
• Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines—Recommendations on the use of biologicals in severe asthma  Academic Article
• Enantioselective Organocatalytic Michael/Aldol Sequence: Anticancer Natural Product (+)-trans-Dihydrolycoricidine  Academic Article
• Epidermal Interleukin-1 is Increased in Cutaneous T-Cell Lymphoma  Academic Article
• Estimation of Pulmonary Deposition of Aerosol Using Gamma Scintigraphy  Academic Article
• Evaluation of synthetic coumarins for antiausterity cytotoxicity against pancreatic cancers  Academic Article
• Evidence-Based Guideline: ACR made 10 strong treatment recommendations for RA, but high-quality evidence was sparse  Academic Article
• Evolving medicinal chemistry strategies in antibiotic discovery  Academic Article
• Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites  Academic Article
• Exploration of Nonribosomal Peptide Families with an Automated Informatic Search Algorithm  Academic Article
• Fast and high-resolution purification of a PEGylated protein using a z2 laterally-fed membrane chromatography device  Academic Article
• Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)  Academic Article
• Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining  Academic Article
• Glycopeptide antibiotic discovery in the genomic era  Chapter
• Heterogeneity in Patient Characteristics and Differences in Treatment Across 4 Canadian Rheumatoid Arthritis Cohorts  Academic Article
• Heterologous Expression and Structural Characterisation of a Pyrazinone Natural Product Assembly Line  Academic Article
• Heterologous expression-facilitated natural products’ discovery in actinomycetes  Academic Article
• High functional diversity among Nitrospira populations that dominate rotating biological contactor microbial communities in a municipal wastewater treatment plant  Academic Article
• Impact of using concomitant conventional DMARDs on adherence to biologic DMARD treatment in rheumatoid arthritis: Multi-centre, population-based cohort study.  Academic Article
• Incidence and prognosis of COVID‐19 in psoriasis patients on biologic therapy: a multicentre retrospective cohort study  Academic Article
• Incorporating Fecal Calprotectin Into Clinical Practice for Patients With Moderate-to-Severely Active Ulcerative Colitis Treated With Biologics or Small-Molecule Inhibitors  Academic Article
• Informatic search strategies to discover analogues and variants of natural product archetypes  Academic Article
• Inspired by nature: investigating tetrataenite for permanent magnet applications  Academic Article
• Long-term safety of biologics in dermatology  Academic Article
• Management of Juvenile Idiopathic Arthritis 2015: A Position Statement from the Pediatric Committee of the Canadian Rheumatology Association  Academic Article
• Modelling the benefits of an optimised treatment strategy for 5-ASA in mild-to-moderate ulcerative colitis  Academic Article
• Monitoring eosinophils to guide therapy with biologics in asthma: does the compartment matter?  Academic Article
• Much ado about Biologicals: Highlights of the Master Class on Biologicals, Prague, 2018  Academic Article
• Natural health product use in Canada: analysis of the National Population Health Survey.  Academic Article
• Nebulisation of surfactants in an animal model of neonatal respiratory distress  Academic Article
• New paradigm in asthma management: Switching between biologics!  Academic Article
• No improvement in disclosure of natural health product use to primary care medical doctors in the last 15 years: A survey of naturopathic patients  Academic Article
• Nonribosomal Assembly of Natural Lipocyclocarbamate Lipoprotein-Associated Phospholipase Inhibitors  Academic Article
• ONS Guidelines™ for Cancer Treatment–Related Hot Flashes in Women With Breast Cancer and Men With Prostate Cancer  Academic Article
• Occurrence of Serious Infection in Patients with Rheumatoid Arthritis Treated with Biologics and Denosumab Observed in a Clinical Setting  Conference Paper
• Opportunities for natural products in 21^st century antibiotic discovery  Academic Article
• PRISM 3: expanded prediction of natural product chemical structures from microbial genomes  Academic Article
• Perspective: Synthetic biology revives antibiotics  Academic Article
• Plasma-derived biological medicines used to promote haemostasis  Academic Article
• Polyphenolic natural products and natural product–inspired steroidal mimics as aromatase inhibitors  Academic Article
• Poractant alfa versus bovine lipid extract surfactant for infants 24+0 to 31+6 weeks gestational age: A randomized controlled trial  Academic Article
• Poractant alfa versus bovine lipid extract surfactant: prospective comparative effectiveness study  Academic Article
• Potential Interactions Between Pharmaceuticals and Natural Health Products in Canada  Academic Article
• Predicting Which Children with Juvenile Idiopathic Arthritis Will Not Attain Early Remission with Conventional Treatment: Results from the ReACCh-Out Cohort  Academic Article
• Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7  Academic Article
• Reducing the risk of bacterial contamination of cellular blood components.  Academic Article
• Reply to Yilmaz: Selection of Biologics for Type 2–High Asthma  Academic Article
• Resolution of dominant patient‐reported outcome at end of induction predicts clinical and endoscopic remission in Crohn’s disease  Academic Article
• Response to placebo in non-renal, non-neuropsychiatric systemic lupus erythematosus: a systematic review and pooled analysis  Academic Article
• Review and Practical Guidance on Managing Fungal Infections in Patients With Psoriasis Receiving Anti-IL-17 Therapies  Academic Article
• Review of Systemic Treatment Options for Adult Atopic Dermatitis  Academic Article
• Role of Biologics in Asthma  Academic Article
• Role of Epidermal Cell Thymocyte-Activating Factor in the Proliferation and Differentiation of Murine B Cells  Academic Article
• Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice  Academic Article
• Self-reported use of natural health products: A cross-sectional telephone survey in older Ontarians  Academic Article
• Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60  Academic Article
• Something old, something new: revisiting natural products in antibiotic drug discovery  Academic Article
• Statistical reanalysis of natural products reveals increasing chemical diversity  Academic Article
• Strategies for target identification of antimicrobial natural products  Academic Article
• Sulfate was a trace constituent of Archean seawater  Academic Article
• Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation  Academic Article
• Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics  Academic Article
• Targeting the Resistance of Pancreatic Cancer Cells to Nutrient Deprivation: Anti-Austerity Compounds  Academic Article
• The Antibiotic Resistome: A Guide for the Discovery of Natural Products as Antimicrobial Agents  Academic Article
• The Effects of Red Yeast Rice Dietary Supplement on Blood Pressure, Lipid Profile and C-reactive Protein in Hypertension: A Systematic Review  Academic Article
• The Joint Task Force on Practice Parameters GRADE guidelines for the medical management of chronic rhinosinusitis with nasal polyposis  Academic Article
• The Real-World Effectiveness and Safety of Ustekinumab in the Treatment of Crohn's Disease: Results From the SUCCESS Consortium  Academic Article
• The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines  Academic Article
• The development of a DNA microarray-based assay for the characterization of commercially formulated microbial products  Academic Article
• The interleukin-13 paradox in asthma: effective biology, ineffective biologicals  Academic Article
• The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort  Academic Article
• Thiopeptides: antibiotics with unique chemical structures and diverse biological activities  Academic Article
• Ulcerative colitis.  Academic Article
• Ultrahigh‐speed, ultrahigh‐resolution preparative separation of protein biopharmaceuticals using membrane chromatography  Academic Article
• Under-Reporting of COVID-19 Infections in Psoriasis Patients on Biologics  Academic Article
• Unlocking the potential of natural products in drug discovery  Academic Article
• Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial  Academic Article
• WHO Expert Committee on Biological Standardization.  Conference Paper
• What drives the comparative effectiveness of biologics vs methotrexate in rheumatoid arthritis? Meta-regression and graphical inspection of suspected clinical factors  Academic Article
• Who Expert Committee on Biological Standardization.  Book
• β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents  Academic Article