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PRISM 3: expanded prediction of natural product...
Journal article

PRISM 3: expanded prediction of natural product chemical structures from microbial genomes

Abstract

Microbial natural products represent a rich resource of pharmaceutically and industrially important compounds. Genome sequencing has revealed that the majority of natural products remain undiscovered, and computational methods to connect biosynthetic gene clusters to their corresponding natural products therefore have the potential to revitalize natural product discovery. Previously, we described PRediction Informatics for Secondary Metabolomes …

Authors

Skinnider MA; Merwin NJ; Johnston CW; Magarvey NA

Journal

Nucleic Acids Research, Vol. 45, No. W1, pp. w49–w54

Publisher

Oxford University Press (OUP)

Publication Date

July 3, 2017

DOI

10.1093/nar/gkx320

ISSN

0305-1048