Journal article
Strategies for target identification of antimicrobial natural products
Abstract
Covering: 2000 to 2015Despite a pervasive decline in natural product research at many pharmaceutical companies over the last two decades, natural products have undeniably been a prolific and unsurpassed source for new lead antibacterial compounds. Due to their inherent complexity, natural extracts face several hurdles in high-throughout discovery programs, including target identification. Target identification and validation is a crucial …
Authors
Farha MA; Brown ED
Journal
Natural Product Reports, Vol. 33, No. 5, pp. 668–680
Publisher
Royal Society of Chemistry (RSC)
Publication Date
May 4, 2016
DOI
10.1039/c5np00127g
ISSN
0265-0568