Journal article
An insight to treat cardiovascular diseases through phytochemicals targeting PPAR-α
Abstract
Peroxisome proliferator-activated receptor-α (PPAR-α) belonging to the nuclear hormone receptor superfamily is a promising target for CVDs which mechanistically improves the production of high-density lipid as well as inhibit vascular smooth muscle cell proliferation. PPAR-α mainly interferes with adenosine monophosphate-activated protein kinase, transforming growth factor-β-activated kinase, and nuclear factor-κB pathways to protect against …
Authors
Sharma S; Sharma D; Dhobi M; Wang D; Tewari D
Journal
Molecular and Cellular Biochemistry, Vol. 479, No. 3, pp. 707–732
Publisher
Springer Nature
Publication Date
3 2024
DOI
10.1007/s11010-023-04755-7
ISSN
0300-8177