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Histological Remission Placebo Rates in Ulcerative...
Journal article

Histological Remission Placebo Rates in Ulcerative Colitis Trials: A Systematic Review and Meta-analysis

Abstract

BACKGROUND: High histologic remission rates have been reported with placebos in randomized controlled trials (RCTs) evaluating ulcerative colitis (UC) therapies and have varied based on trial designs. We performed a systematic review and meta-analysis to quantify placebo histological remission rates and identify factors influencing those rates. METHODS: MEDLINE, EMBASE, and the Cochrane library were searched from inception of the databases …

Authors

Youssef M; Dong K; Lee SJ; Narula N

Journal

Inflammatory Bowel Diseases, Vol. 30, No. 1, pp. 125–131

Publisher

Oxford University Press (OUP)

Publication Date

January 5, 2024

DOI

10.1093/ibd/izad013

ISSN

1078-0998