Treatment Failure
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BCR–ABL1 transcript doubling time as a predictor for treatment‐free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase Academic Article
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A Canadian phase II study evaluating the efficacy of rituximab in the management of patients with relapsed/refractory thrombotic thrombocytopenic purpura Conference Paper
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A Controlled Trial of Oral Acyclovir for Iridocyclitis Caused by Herpes Simplex Virus Academic Article
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A Phase II study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and gemcitabine in advanced pancreatic carcinoma. A trial of the Princess Margaret Hospital Phase II consortium Academic Article
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A comparison of physical and psychological features of responders and non-responders to cervical facet blocks in chronic whiplash Academic Article
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A phase II study of AT9283, an aurora kinase inhibitor, in patients with relapsed or refractory multiple myeloma: NCIC clinical trials group IND.191 Academic Article
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A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer Academic Article
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A phase II trial of ZD1839 (Iressa™) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer Academic Article
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A systematic survey of randomised trials that stopped early for reasons of futility Academic Article
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A wake-up call for global access to salvage HIV drug regimens Academic Article
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A well-conducted randomized trial that establishes no benefit of therapy is an important medical advance Academic Article
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ACG Clinical Guideline: Treatment of Helicobacter pylori Infection Academic Article
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Adequacy of dialysis and nutrition in continuous peritoneal dialysis Academic Article
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Advanced Ovarian Cancer: Phase III Randomized Study of Sequential Cisplatin–Topotecan and Carboplatin–Paclitaxel vs Carboplatin–Paclitaxel Academic Article
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Age, Gender, Race, and Associations With Kidney Failure Following Living Kidney Donation Academic Article
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Allogeneic Mesenchymal Stem Cells for Treatment of AKI after Cardiac Surgery Academic Article
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An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy Academic Article
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Antibiotic exposure and ‘response failure’ for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care Academic Article
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Antibiotic treatment failure in four common infections in UK primary care 1991-2012: longitudinal analysis Academic Article
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Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls Academic Article
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Are Elderly Patients at Increased Risk of Complications Following Pacemaker Implantation? A Meta-Analysis of Randomized Trials Academic Article
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Are some children with empyema at risk for treatment failure with fibrinolytics? A multicenter cohort study Academic Article
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Aspirin in Patients Undergoing Noncardiac Surgery Academic Article
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Assumptions of Expected Benefits in Randomized Phase III Trials Evaluating Systemic Treatments for Cancer Academic Article
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Asthma that is unresponsive to usual care Academic Article
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Autologous Stem Cell Transplantation in Follicular Lymphoma: a Systematic Review and Meta-analysis Academic Article
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B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke Academic Article
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Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis Academic Article
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Bouveret Syndrome: When There Are No Options Academic Article
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Canadian Guidelines for the Management of Acute Exacerbations of Chronic Bronchitis Academic Article
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Characterization of Operator Learning Curve for Transradial Coronary Interventions Academic Article
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Clinical Outcomes of Failing to Dose-Reduce Cephalosporin Antibiotics in Older Adults with CKD Academic Article
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Clonidine in Patients Undergoing Noncardiac Surgery Academic Article
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Comparative effectiveness of tenofovir in HIV-infected treatment-experienced patients: systematic review and meta-analysis Academic Article
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Compression ultrasonography for false femoral artery aneurysms: Hypocoagulability is a cause of failure Academic Article
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Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions Academic Article
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Continuous Erector Spinae Plane Block for Rescue Analgesia in Thoracotomy After Epidural Failure: A Case Report. Academic Article
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Contralateral Cerebral Infarction Following Vacuum Extraction Academic Article
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Correlates of clinical failure in ventilator-associated pneumonia: insights from a large, randomized trial Academic Article
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Creatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1 Academic Article
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Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease Academic Article
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Decreased Glenoid Retroversion Is a Risk Factor for Failure of Primary Arthroscopic Bankart Repair in Individuals With Subcritical Bone Loss Versus No Bone Loss Academic Article
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Differentiating Ventricular From Supraventricular Arrhythmias Using the Postpacing Interval After Failed Antitachycardia Pacing Academic Article
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Disseminated Tumor Embolism From Breast Cancer Leading to Multiorgan Failure Academic Article
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Does 3-Day Course of Oral Amoxycillin Benefit Children of Non-Severe Pneumonia with Wheeze: A Multicentric Randomised Controlled Trial Academic Article
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Early Closure of the Watterberg Trial Academic Article
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Editorial Commentary: Labral Reconstruction: Some Early Positive Signals, and Now the Challenge Is Ours Academic Article
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Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19 Academic Article
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Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis Academic Article
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Effect of Everolimus on Bone Marker Levels and Progressive Disease in Bone in
BOLERO-2 Academic Article
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Effect of Lipid Lowering With Rosuvastatin on Progression of Aortic Stenosis Academic Article
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Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome Academic Article
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Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes Academic Article
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Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients Academic Article
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Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy Academic Article
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Effectiveness and safety of abciximab after failed thrombolytic therapy Academic Article
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Effects of Combination Lipid Therapy in Type 2 Diabetes Mellitus Academic Article
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Effects of Intensive Glucose Lowering in Type 2 Diabetes Academic Article
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Effects of Lowering Homocysteine Levels With B Vitamins on Cardiovascular Disease, Cancer, and Cause-Specific Mortality<subtitle>Meta-analysis of 8 Randomized Trials Involving 37 485 Individuals</subtitle><alt-title>Effects of Lowering Homocysteine Levels</alt-title> Academic Article
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Effects of antithyroid drugs on radioiodine treatment: systematic review and meta-analysis of randomised controlled trials Academic Article
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Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate renal insufficiency: Results of the HOPE Study Academic Article
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Effects on Thrombin Generation of Single Injections of Hirulog™ in Patients with Calf Vein Thrombosis Academic Article
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Efficacy of 5-Aminosalicylates in Ulcerative Colitis: Systematic Review and Meta-Analysis Academic Article
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Efficacy of Biological Therapies in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis Academic Article
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Efficacy of Immunosuppressive Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis Academic Article
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Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: systematic review and network meta-analysis Academic Article
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Eradication of Hepatitis C Virus Infection and the Development of Hepatocellular Carcinoma Academic Article
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Eradication ofHelicobacter pylori: Omeprazole in Combination with Antibiotics Conference Paper
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Etanercept for patients with psoriasis who did not respond or who lost their response to adalimumab or infliximab Academic Article
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Evaluation of Clinical and Sonographic Features in 55 Children with Tularemia Academic Article
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Failed Pyeloplasty in Children: Comparative Analysis of Retrograde Endopyelotomy Versus Redo Pyeloplasty Conference Paper
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Failure Mechanisms and Neoatherosclerosis Patterns in Very Late Drug-Eluting and Bare-Metal Stent Thrombosis Academic Article
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Failure of Aspirin to Prevent Atherothrombosis Academic Article
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Failure of Protein to Improve Time Trial Performance when Added to a Sports Drink Academic Article
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Failure of aneurysm occlusion by flow diverter: a role for surgical bypass and parent artery occlusion Academic Article
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Failure of montelukast to reduce sputum eosinophilia in high-dose corticosteroid-dependent asthma Academic Article
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Fluoroquinolones in Children With Fever and Neutropenia Academic Article
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GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength Academic Article
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Genetic variability and characterization of non-structural region 5 of hepatitis C virus genome from Chinese patients Academic Article
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Germ Cell Transplantation in an Azoospermic Klinefelter Bull1 Academic Article
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Glucocorticosteroid Therapy in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis Academic Article
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Grade 3 ischemia on the admission electrocardiogram predicts failure of ST resolution and of adequate flow restoration after primary percutaneous coronary intervention for acute myocardial infarction Academic Article
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Health Care Costs of Peritoneal Dialysis Technique Failure and Dialysis Modality Switching Academic Article
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High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome Academic Article
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Host Genetic Determinants Associated With Helicobacter pylori Eradication Treatment Failure: A Systematic Review and Meta-analysis Academic Article
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Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19 Academic Article
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Hypothermia Therapy after Traumatic Brain Injury in Children Academic Article
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Identifying Factors Most Important to Lower Extremity Trauma Patients: Key Concepts from the Development of a Patient-Reported Outcome Instrument for Lower Extremity Trauma, The LIMB-Q Academic Article
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Impact of antibiotic treatment duration on outcomes in older men with suspected urinary tract infection: Retrospective cohort study Academic Article
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Incidence and Treatment Outcomes of PharyngealNeisseria gonorrhoeaeandChlamydia trachomatisInfections in Men Who Have Sex with Men: A 13‐Year Retrospective Cohort Study Academic Article
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Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. The Canada-USA (CANUSA) Peritoneal Dialysis Study Group. Academic Article
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Indications for Surgical Management of Osteochondritis Dissecans of the Knee in the Pediatric Population: A Systematic Review Academic Article
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Individualized 131I-mIBG therapy in the management of refractory and relapsed neuroblastoma Academic Article
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Induction failure in acute lymphoblastic leukemia of childhood Academic Article
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Intramedullary Nailing Versus Plate Fixation for the Treatment Displaced Midshaft Clavicular Fractures: A Systematic Review and Meta-Analysis Academic Article
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Intravenous and Oral Itraconazole versus Intravenous Amphotericin B Deoxycholate as Empirical Antifungal Therapy for Persistent Fever in Neutropenic Patients with Cancer Who Are Receiving Broad-Spectrum Antibacterial Therapy Academic Article
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Irbesartan in Patients with Atrial Fibrillation Academic Article
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Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction Academic Article
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Is there a role for laboratory testing to identify patients at risk of aspirin treatment failure? Academic Article
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Is there a role for laboratory testing to identify patients at risk of aspirin treatment failure? Academic Article
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Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women Academic Article
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Laparoscopic sleeve gastrectomy versus laparoscopic gastric bypass: A retrospective cohort study Academic Article
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Laparoscopic splenectomy in chronic idiopathic thrombocytopenic purpura Academic Article
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Lateral Extra-articular Tenodesis Reduces Failure of Hamstring Tendon Autograft Anterior Cruciate Ligament Reconstruction: 2-Year Outcomes From the STABILITY Study Randomized Clinical Trial Academic Article
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Learning from failure-rationale and design for a study about discontinuation of randomized trials (DISCO study) Academic Article
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Levofloxacin-based rescue regimens after Helicobacter pylori treatment failure: how strong is the evidence? Academic Article
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Life table (survival) analysis to generate cumulative pregnancy rates in assisted reproduction: are we overestimating our success rates? Academic Article
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Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome Academic Article
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Measles immunization strategy: measles antibody response following MMR II vaccination of children at one year of age. Academic Article
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Medical abortion: what does the research tell us? Academic Article
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Meta-Analysis Academic Article
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Mexiletine or catheter ablation after amiodarone failure in the VANISH trial Academic Article
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Millimetre wave therapy for pain relief after total knee arthroplasty: A randomised controlled trial Academic Article
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Misdiagnosis of bipolar disorder as borderline personality disorder: clinical and economic consequences Academic Article
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Monoclonal antibodies for the treatment of refractory asthma Academic Article
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Multicenter Randomized Controlled Trial of Terlipressin Versus Sclerotherapy in the Treatment of Acute Variceal Bleeding: The TEST Study Academic Article
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Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis Academic Article
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Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial Academic Article
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Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy Academic Article
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No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: Results of two randomized, double-blind, placebo-controlled clinical trials Academic Article
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Non-invasive high-frequency ventilation versus bi-phasic continuous positive airway pressure (BP-CPAP) following CPAP failure in infants <1250 g: a pilot randomized controlled trial Academic Article
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Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies Academic Article
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Outpatient and oral antibiotic management of low-risk febrile neutropenia are effective in children—a systematic review of prospective trials Academic Article
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Pancreatic Enzyme Supplements Are Not Effective for Relieving Abdominal Pain in Patients with Chronic Pancreatitis: Meta-Analysis and Systematic Review of Randomized Controlled Trials Academic Article
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Patient factors that predict failure of omeprazole, clarithromycin, and tinidazole to eradicateHelicobacter pylori Academic Article
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Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer Academic Article
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Penile brachytherapy: Results for 49 patients Academic Article
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Persistent genital arousal disorder: a clinical challenge Academic Article
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Phase II Stopping Rules That Employ Response Rates and Early Progression Academic Article
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Phase II/III randomized trial of TCH346 in patients with ALS Academic Article
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Predicting Which Children with Juvenile Idiopathic Arthritis Will Not Attain Early Remission with Conventional Treatment: Results from the ReACCh-Out Cohort Academic Article
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Predictors of Failure after Pancreaticoduodenectomy for Ampullary Carcinoma Academic Article
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Predictors of Skeletal Complications in Men with Hormone-Refractory Metastatic Prostate Cancer Academic Article
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Prednisolone andMycobacterium indicus praniiin Tuberculous Pericarditis Academic Article
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Prevention of Syncope Trial (POST) Academic Article
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Primary arthroscopic repair of massive rotator cuff tears results in significant improvements with low rate of re-tear Academic Article
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Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections Academic Article
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Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections Academic Article
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Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Academic Article
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Prognostic value of procalcitonin in respiratory tract infections across clinical settings Academic Article
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Prospective, Multisite, International Comparison of 18F-Fluoromethylcholine PET/CT, Multiparametric MRI, and 68Ga-HBED-CC PSMA-11 PET/CT in Men with High-Risk Features and Biochemical Failure After Radical Prostatectomy: Clinical Performance and Patient Outcomes Academic Article
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Psychopharmacologic treatment of pediatric major depressive disorder Academic Article
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Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial) Academic Article
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Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder: a double-blind, randomised, placebo-controlled study [ISRCTN83050762] Academic Article
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Randomized Phase II Study of Docetaxel and Prednisone With or Without OGX-011 in Patients With Metastatic Castration-Resistant Prostate Cancer Conference Paper
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Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy Academic Article
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Randomized trial of insulin versus usual care in reducing restenosis after coronary intervention in patients with diabetes. the STent Restenosis And Metabolism (STREAM) study Academic Article
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Rationale and design of AVERROES: Apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment Academic Article
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Reamed Versus Nonreamed Intramedullary Nailing of Lower Extremity Long Bone Fractures: A Systematic Overview and Meta-analysis Academic Article
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Reasons for resistance to aspirin in cardiovascular disease. Academic Article
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Recommendations for advancing the care of Canadians living with refractory angina pectoris: A Canadian Cardiovascular Society position statement Academic Article
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Recurrence of Dialysis Shunt Pseudoaneurysm Following Percutaneous Thrombin Embolization Academic Article
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Refractory Primary Central Nervous System Vasculitis of Childhood: Successful Treatment with Infliximab Academic Article
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Regular Monitoring of Access Flow Compared with Monitoring of Venous Pressure Fails to Improve Graft Survival Academic Article
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Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori Academic Article
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Rescue Angioplasty or Repeat Fibrinolysis After Failed Fibrinolytic Therapy for ST-Segment Myocardial Infarction Academic Article
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Retention in care and virological failure among adult HIV+ patients on second-line ART in Rwanda: a national representative study Academic Article
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Revisional surgery after failed laparoscopic adjustable gastric banding: a systematic review Conference Paper
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Risankizumab in Severe Asthma — A Phase 2a, Placebo-Controlled Trial Academic Article
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Risk Factors for Treatment Failure With Antiosteoporosis Medication: The Global Longitudinal Study of Osteoporosis in Women (GLOW) Academic Article
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Risk Factors of Cellulitis Treatment Failure with Once-Daily Intravenous Cefazolin Plus Oral Probenecid Academic Article
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Role of Carnitine Supplementation in Apnea of Prematurity: A Systematic Review Academic Article
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SHOULD ALL UROLOGISTS PERFORMING VASECTOMY REVERSALS BE ABLE TO PERFORM VASOEPIDIDYMOSTOMIES IF REQUIRED? Academic Article
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Short course versus 7-day course of intravenous antibiotics for probable neonatal septicemia: A pilot, open-label, randomized controlled trial Academic Article
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Shorter Versus Longer-term Antibiotic Treatments for Community-Acquired Pneumonia in Children: A Meta-analysis Academic Article
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Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811 Conference Paper
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Subcutaneous IGF-1 is not beneficial in 2-year ALS trial Academic Article
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Surgical approach after failed enteryx injection for GERD. Academic Article
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Telmisartan to Prevent Recurrent Stroke and Cardiovascular Events Academic Article
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The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for malignant glioma Academic Article
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The Burden of Treatment Failure in Type 2 Diabetes Academic Article
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The Hunt for New Tuberculosis Vaccines: Anti-TB Immunity and Rational Design of Vaccines Academic Article
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The Poorly Explored Impact of Uncontrolled Asthma Academic Article
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The Predictive Value of Early Assessment After 1 Cycle of Induction Chemotherapy with 18F-FDG PET/CT and Diffusion-Weighted MRI for Response to Radical Chemoradiotherapy in Head and Neck Squamous Cell Carcinoma Academic Article
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The Pursuit of Clinically Relevant Measures of Platelet Function After Antiplatelet Drug Therapy⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology. Academic Article
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The REVision Using Imaging to Guide Staging and Evaluation (REVISE) in ACL Reconstruction Classification Academic Article
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The Stability study: a protocol for a multicenter randomized clinical trial comparing anterior cruciate ligament reconstruction with and without Lateral Extra-articular Tenodesis in individuals who are at high risk of graft failure Academic Article
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The Use of Transcutaneous Oximetry to Predict Healing Complications of Lower Limb Amputations: A Systematic Review and Meta-analysis Academic Article
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The association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy Academic Article
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The association of platelets with failed patent ductus arteriosus closure after a primary course of indomethacin or ibuprofen: a systematic review and meta-analysis Academic Article
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The use of preoperative radiotherapy in the management of patients with clinically resectable rectal cancer: a practice guideline Academic Article
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The use of the impingement test as a predictor of outcome following subacromial decompression for rotator cuff tendinosis Academic Article
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Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 Academic Article
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Treatment after failure: the problem of "non-responders" Academic Article
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Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis Academic Article
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Treatment failure in osteoporosis Academic Article
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Treatment of Acute Otitis Media in Children Academic Article
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Treatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings Academic Article
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Use of Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers and Cardiovascular Outcomes in Chronic Dialysis Patients: A Population-Based Cohort Study Academic Article
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Vasopressin versus Norepinephrine Infusion in Patients with Septic Shock Academic Article
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Virologic failure in people living with HIV in 1st line ART: A 10-year Mexican population-based study Academic Article
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Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients Academic Article
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When Is Recalcitrant Pyoderma Gangrenosum Truly Recalcitrant? Academic Article
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When Midazolam Fails Academic Article
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When is Recalcitrant Pyoderma Gangrenosum Truly Recalcitrant? Academic Article
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n–3 Fatty Acids and Cardiovascular Outcomes in Patients with Dysglycemia Academic Article