Journal article
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19
Abstract
BACKGROUND: Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid-19.
METHODS: In an open-label, adaptive, multiplatform, randomized clinical trial, critically ill patients with severe Covid-19 were randomly assigned to a pragmatically defined regimen of …
Authors
Goligher EC; Bradbury CA; McVerry BJ; Lawler PR; Berger JS; Gong MN; Carrier M; Reynolds HR; Kumar A; Turgeon AF
Journal
The New England Journal of Medicine, Vol. 385, No. 9, pp. 777–789
Publisher
Massachusetts Medical Society
Publication Date
August 26, 2021
DOI
10.1056/nejmoa2103417
ISSN
0028-4793