Journal article
Genetic variability and characterization of non-structural region 5 of hepatitis C virus genome from Chinese patients
Abstract
Abstract: Sequence variation in the putative nonstructural region 5b (NS5b) of hepatitis C virus (HCV) was analyzed in China. Complementary DNA fragments from sera of 49 Chinese patients were amplified by polymerase chain reaction (PCR) and the products were cloned and sequenced. Based on the comparison in NS5b of 33 clones of genotype 1b and 16 clones of genotype 2a, Chinese isolates of HCV belong to the same subtype as HCV-J, and HC-J6 from …
Authors
Wei L; Wang Y; Du S; Wang H; Tao Q
Journal
Journal of Gastroenterology, Vol. 33, No. 1, pp. 62–72
Publisher
Springer Nature
Publication Date
January 1998
DOI
10.1007/s005350050046
ISSN
0944-1174
Associated Experts
Fields of Research (FoR)
Sustainable Development Goals (SDG)
Medical Subject Headings (MeSH)
AdultAsian PeopleBase SequenceDNA PrimersFemaleGenotypeHepacivirusHumansMaleMiddle AgedMolecular Sequence DataPolymerase Chain ReactionRegulatory Sequences, Nucleic AcidTranscription, GeneticAgedAged, 80 and overAnti-Bacterial AgentsClarithromycinDrug Resistance, MicrobialDrug Therapy, CombinationHelicobacter InfectionsHelicobacter pyloriMicrobial Sensitivity TestsNitroimidazolesOmeprazoleTinidazoleTreatment Failure