Journal article
Efficacy of Biological Therapies in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis
Abstract
OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory disorders of the gastrointestinal tract of unknown etiology. Evidence for treatment of the condition with biological therapies exists, but no systematic review and meta-analysis has examined this issue in its entirety.
METHODS: MEDLINE, EMBASE, and the Cochrane central register of controlled trials were searched (through to December 2010). Trials recruiting adults …
Authors
Ford AC; Sandborn WJ; Khan KJ; Hanauer SB; Talley NJ; Moayyedi P
Journal
The American Journal of Gastroenterology, Vol. 106, No. 4,
Publisher
Wolters Kluwer
Publication Date
April 2011
DOI
10.1038/ajg.2011.73
ISSN
0002-9270
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Anti-Inflammatory AgentsAntibodiesAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBiological TherapyColitis, UlcerativeCrohn DiseaseHumansInfliximabIntegrin alpha4NatalizumabRandomized Controlled Trials as TopicRemission InductionRiskSecondary PreventionSeverity of Illness IndexTreatment FailureTreatment OutcomeTumor Necrosis Factor-alphaWound Healing