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Prednisolone and Mycobacterium indicus pranii in...
Journal article

Prednisolone and Mycobacterium indicus pranii in Tuberculous Pericarditis

Abstract

BACKGROUND: Tuberculous pericarditis is associated with high morbidity and mortality even if antituberculosis therapy is administered. We evaluated the effects of adjunctive glucocorticoid therapy and Mycobacterium indicus pranii immunotherapy in patients with tuberculous pericarditis. METHODS: Using a 2-by-2 factorial design, we randomly assigned 1400 adults with definite or probable tuberculous pericarditis to either prednisolone or placebo …

Authors

Mayosi BM; Ntsekhe M; Bosch J; Pandie S; Jung H; Gumedze F; Pogue J; Thabane L; Smieja M; Francis V

Journal

The New England Journal of Medicine, Vol. 371, No. 12, pp. 1121–1130

Publisher

Massachusetts Medical Society

Publication Date

September 18, 2014

DOI

10.1056/nejmoa1407380

ISSN

0028-4793