Journal article
Effects of Intensive Glucose Lowering in Type 2 Diabetes
Abstract
BACKGROUND: Epidemiologic studies have shown a relationship between glycated hemoglobin levels and cardiovascular events in patients with type 2 diabetes. We investigated whether intensive therapy to target normal glycated hemoglobin levels would reduce cardiovascular events in patients with type 2 diabetes who had either established cardiovascular disease or additional cardiovascular risk factors.
METHODS: In this randomized study, 10,251 …
Authors
Gerstein HC; Miller ME; Byington RP; Goff DC; Bigger JT; Buse JB; Cushman WC; Genuth S; Ismail-Beigi F; Grimm RH
Journal
The New England Journal of Medicine, Vol. 358, No. 24, pp. 2545–2559
Publisher
Massachusetts Medical Society
Publication Date
June 12, 2008
DOI
10.1056/nejmoa0802743
ISSN
0028-4793