Laparoscopic splenectomy in chronic idiopathic thrombocytopenic purpura Journal Articles

abstract

• Splenectomy remains the definitive treatment for idiopathic thrombocytopenic purpura (ITP). Issues related to timing of splenectomy, perioperative management of platelet count, deep vein thrombosis prophylaxis, and preoperative vaccination are not standardized. Predicting the outcome of splenectomy is desirable but, again, consistent evidence for a particular approach is lacking. Laparoscopic splenectomy, first introduced in 1991, has removed some of the barriers to acceptance of splenectomy and may well change its place in the various treatment algorithms. This article reviews current knowledge with respect to laparoscopic splenectomy and provides an analysis of current evidence regarding issues of safety, efficacy, and cost effectiveness. Surgical technique is briefly reviewed. The information is drawn from a comprehensive analysis of the literature, as well as my own large experience with laparoscopic splenectomy, the majority of which has been focused on laparoscopic splenectomy for ITP.

authors

• Marcaccio, Michael Joseph

status

• published 

publication date

• July 2000

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• Chronic Disease (MeSH)
• Costs and Cost Analysis (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• Laparoscopy (MeSH)
• Purpura, Thrombocytopenic, Idiopathic (MeSH)
• Splenectomy (MeSH)
• Treatment Failure (MeSH)

published in

• Seminars in Hematology  Journal

keywords

• Chronic Disease
• Costs and Cost Analysis
• Humans
• Laparoscopy
• Purpura, Thrombocytopenic, Idiopathic
• Splenectomy
• Treatment Failure

Digital Object Identifier (DOI)

• 10.1016/s0037-1963(00)90105-7

PubMed ID

• 10942221

start page

• 267

end page

• 274

volume

• 37

issue

• 3