Journal article
Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women
Abstract
BACKGROUND: The antibiotic nitrofurantoin is commonly used to treat uncomplicated urinary tract infections. However, when this drug is used by patients with reduced kidney function, its urine concentration may be subtherapeutic.
METHODS: We conducted a population-based study of older women (mean age 79 years) in Ontario, Canada, whose estimated glomerular filtration rate was relatively low (median 38 mL/min per 1.73 m(2)) and for whom 1 of 4 …
Authors
Singh N; Gandhi S; McArthur E; Moist L; Jain AK; Liu AR; Sood MM; Garg AX
Journal
Canadian Medical Association Journal, Vol. 187, No. 9, pp. 648–656
Publisher
Joule
Publication Date
June 16, 2015
DOI
10.1503/cmaj.150067
ISSN
0820-3946