Journal article
Monoclonal antibodies for the treatment of refractory asthma
Abstract
PURPOSE OF REVIEW: A small proportion of patients with asthma have severe disease characterized by persistent airflow obstruction, airway hyperresponsiveness and eosinophilic airway inflammation. This review focuses on the clinical efficacy of inhibiting T helper 2-cytokine-mediated inflammatory responses using monoclonal antibodies directed against immunoglobulin E (IgE), interleukin (IL)-5, and IL-4/IL-13 in patients with severe refractory …
Authors
Hambly N; Nair P
Journal
Current Opinion in Pulmonary Medicine, Vol. 20, No. 1, pp. 87–94
Publisher
Wolters Kluwer
Publication Date
1 2014
DOI
10.1097/mcp.0000000000000007
ISSN
1070-5287