Transforming Growth Factor beta1 Concept

subject area of

• A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.  Journal Articles
• Activin and transforming growth factor-β as local regulators of ovarian steroidogenesis in the goldfish  Journal Articles
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.  Journal Articles
• Adenoviral Gene Transfer of Connective Tissue Growth Factor in the Lung Induces Transient Fibrosis  Journal Articles
• Adenoviral-Mediated Gene Transfer into Bone Marrow: An Effective Surgical Technique in Rat  Journal Articles
• Adenovirus-Mediated Gene Transfer of TGF-β1 to the Renal Glomeruli Leads to Proteinuria  Journal Articles
• Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice.  Journal Articles
• Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels  Journal Articles
• Antifibrotic Effects of a Recombinant Adeno-Associated Virus Carrying Small Interfering RNA Targeting TIMP-1 in Rat Liver Fibrosis  Journal Articles
• Antifibrotic Role of αB-Crystallin Inhibition in Pleural and Subpleural Fibrosis  Journal Articles
• Association between Markers of Inflammation, Fibrosis and Hypervolemia in Peritoneal Dialysis Patients  Journal Articles
• B Cells Are Not Involved in the Regulation of Adenoviral TGF-β1– or Bleomycin-Induced Lung Fibrosis in Mice  Journal Articles
• Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin‐induced thrombocytopenia  Journal Articles
• Complex two-gene modulation of lung disease severity in children with cystic fibrosis  Journal Articles
• Connective Tissue Growth Factor Is Crucial to Inducing a Profibrotic Environment in “Fibrosis-Resistant” Balb/c Mouse Lungs  Journal Articles
• Connective-Tissue Growth Factor Contributes to TGF-β1–induced Lung Fibrosis  Journal Articles
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Journal Articles
• Differential expression of nerve growth factor transcripts in glia and neurons and their regulation by transforming growth factor-β1  Journal Articles
• Disruption of β-catenin/CBP signaling inhibits human airway epithelial–mesenchymal transition and repair  Journal Articles
• Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells  Journal Articles
• Effect of Human Wharton's Jelly Mesenchymal Stem Cell Paracrine Signaling on Keloid Fibroblasts  Journal Articles
• Effect of Tangnaikang on TGF-β1-induced transdifferentiation of human renal tubular epithelial HK-2 cells  Journal Articles
• Epithelial Expression of Profibrotic Mediators in a Model of Allergen-Induced Airway Remodeling  Journal Articles
• Exploring alveolar recruitability using positive end-expiratory pressure in mice overexpressing TGF-β1: a structure–function analysis  Journal Articles
• Fibrotic extracellular matrix induces release of extracellular vesicles with pro-fibrotic miRNA from fibrocytes  Journal Articles
• Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum  Journal Articles
• Genetic Modifiers of Liver Disease in Cystic Fibrosis  Journal Articles
• Genetic determinants of right-ventricular remodeling after tetralogy of Fallot repair  Journal Articles
• Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis  Journal Articles
• Gremlin Promotes Peritoneal Membrane Injury in an Experimental Mouse Model and Is Associated with Increased Solute Transport in Peritoneal Dialysis Patients  Journal Articles
• HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells  Journal Articles
• High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation  Journal Articles
• Human antigen R promotes lung fibroblast differentiation to myofibroblasts and increases extracellular matrix production  Journal Articles
• Human milk composition differs in healthy mothers and mothers with celiac disease  Journal Articles
• Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis  Journal Articles
• Induction of Bystander Response in Human Glioma Cells using High-Energy Electrons: A Role for TGF-β1  Journal Articles
• Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation  Journal Articles
• Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair  Journal Articles
• Latent TGF‐β1 is Compartmentalized Between Blood and Seminal Plasma of HIV‐Positive Men and Its Activation in Semen is Negatively Correlated with Viral Load and Immune Activation  Journal Articles
• Lens-Specific Expression of TGF-β Induces Anterior Subcapsular Cataract Formation in the Absence of Smad3  Journal Articles
• Lysyl Oxidase–Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-β1–induced Pulmonary Fibrosis  Journal Articles
• Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension  Journal Articles
• Matrix Metalloproteinase-9–Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation  Journal Articles
• Matrix abnormalities in pulmonary fibrosis  Journal Articles
• Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis  Conferences
• Mechanisms Underlying the Maintenance of Muscle Hypercontractility in a Model of Postinfective Gut Dysfunction  Journal Articles
• Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice  Journal Articles
• Myofibroblast Markers and Microscopy Detection Methods in Cell Culture and Histology  Chapters
• Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts  Journal Articles
• Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis  Journal Articles
• Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats  Journal Articles
• Overexpression of transforming growth factor- 1 in fetal monkey lung results in prenatal pulmonary fibrosis  Journal Articles
• Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis  Journal Articles
• PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells  Journal Articles
• Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling  Journal Articles
• Peritoneal morphological and functional changes associated with platelet-derived growth factor B  Journal Articles
• Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor  Journal Articles
• Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3  Journal Articles
• Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus  Journal Articles
• RETRACTED ARTICLE: Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells  Journal Articles
• Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression  Journal Articles
• Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3  Journal Articles
• Repetitive invasive lung function maneuvers do not accentuate experimental fibrosis in mice  Journal Articles
• Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study  Journal Articles
• SNPs in the bovine IL-10 receptor are associated with somatic cell score in Canadian dairy bulls  Journal Articles
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Journal Articles
• SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells  Journal Articles
• SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells  Journal Articles
• Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis  Journal Articles
• Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin  Journal Articles
• Stretch-induced Activation of Transforming Growth Factor-β₁ in Pulmonary Fibrosis  Journal Articles
• Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis  Journal Articles
• Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo  Journal Articles
• TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium  Journal Articles
• TGF-β1 Induces Progressive Pleural Scarring and Subpleural Fibrosis  Journal Articles
• TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis  Journal Articles
• TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling  Journal Articles
• The Human Papilloma Virus E7 Oncoprotein Inhibits Transforming Growth Factor-β Signaling by Blocking Binding of the Smad Complex to Its Target Sequence  Journal Articles
• The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis  Journal Articles
• Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases  Journal Articles
• Transcriptional profiling and regulation of the extracellular matrix during muscle regeneration  Journal Articles
• Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia  Journal Articles
• Transforming Growth Factor-β1-Mediated Neuroprotection against Excitotoxic Injuryin Vivo  Journal Articles
• Transforming Growth Factor-β: Importance in Long-Term Peritoneal Membrane Changes  Conferences
• Transient Overexpression of TGF-β1 Induces Epithelial Mesenchymal Transition in the Rodent Peritoneum  Journal Articles
• Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis  Journal Articles
• VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats  Journal Articles
• Vascular–Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling  Conferences
• WNT signaling is required for peritoneal membrane angiogenesis  Journal Articles
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Journal Articles
• miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis  Journal Articles
• miR299a-5p promotes renal fibrosis by suppressing the antifibrotic actions of follistatin  Journal Articles