Neoplastic Stem Cells Concept

subject area of

• A Cancer Stem Cell Model for Studying Brain Metastases From Primary Lung Cancer  Journal Articles
• A Patient-Derived Xenograft Model of Glioblastoma  Journal Articles
• A novel stem cell culture model of recurrent glioblastoma  Journal Articles
• A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia  Journal Articles
• A role for GPx3 in activity of normal and leukemia stem cells  Journal Articles
• Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients  Journal Articles
• Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity  Journal Articles
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Journal Articles
• Amplification of MUC1 in prostate cancer metastasis and CRPC development  Journal Articles
• Antagonists of the serotonin receptor 5A target human breast tumor initiating cells  Journal Articles
• Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2  Journal Articles
• BMI1 is a therapeutic target in recurrent medulloblastoma  Conferences
• BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ  Journal Articles
• Biting into a union of oncology and metabolism through leukemic stem cells  Journal Articles
• Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells  Journal Articles
• Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells  Journal Articles
• Brain Metastasis-Initiating Cells: Survival of the Fittest  Journal Articles
• Breast cancer stem-like cells can promote metastasis by activating platelets and down-regulating antitumor activity of natural killer cells  Journal Articles
• CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence  Journal Articles
• Cancer Gastric Chemoprevention: Isolation of Gastric Tumor-Initiating Cells  Journal Articles
• Cancer Stem Cells: Current Challenges and Future Perspectives  Chapters
• Cancer stem cells in nervous system tumors  Journal Articles
• Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations  Journal Articles
• Characterization of brain cancer stem cells: a mathematical approach  Journal Articles
• Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells  Journal Articles
• Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma  Conferences
• Childhood Medulloblastoma: An Overview  Chapters
• Clinical–pathologic significance of cancer stem cell marker expression in familial breast cancers  Journal Articles
• Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors  Journal Articles
• Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations  Journal Articles
• Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway  Journal Articles
• Concepts of human leukemic development  Journal Articles
• Contribution of Host-Derived Tissue Factor to Tumor Neovascularization  Journal Articles
• Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma  Journal Articles
• Culture and Isolation of Brain Tumor Initiating Cells  Journal Articles
• Culture and Isolation of Brain Tumor Initiating Cells  Journal Articles
• Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice  Journal Articles
• Development of a Patient-Derived Xenograft Model Using Brain Tumor Stem Cell Systems to Study Cancer  Journal Articles
• Differentiation of Brain Tumor Initiating Cells  Chapters
• Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance  Journal Articles
• Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma  Journal Articles
• EMT: Mechanisms and therapeutic implications  Journal Articles
• EPH Profiling of BTIC Populations in Glioblastoma Multiforme Using CyTOF  Journal Articles
• Elevated tissue factor procoagulant activity in CD133‐positive cancer cells  Journal Articles
• Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia  Journal Articles
• Estrogen receptor of breast cancer stem cells depending on the original breast cancers  Journal Articles
• Evidence for the transmission of neoplastic properties from transformed to normal human stem cells  Journal Articles
• Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion  Journal Articles
• Flow Cytometric Analysis of Brain Tumor Stem Cells  Chapters
• FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells  Journal Articles
• From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration  Journal Articles
• GBM secretome induces transient transformation of human neural precursor cells  Journal Articles
• Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer  Journal Articles
• Generation of Murine Xenograft Models of Brain Tumors from Primary Human Tissue for In Vivo Analysis of the Brain Tumor-Initiating Cell  Journal Articles
• Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression.  Journal Articles
• Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells  Journal Articles
• Identification of T-lymphocytic leukemia–initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease  Journal Articles
• Identification of a cancer stem cell in human brain tumors.  Journal Articles
• In Vitro Self-Renewal Assays for Brain Tumor Stem Cells  Chapters
• Introduction to Brain Tumor Stem Cells  Chapters
• Introduction to Cancer Stem Cells: Past, Present, and Future  Chapters
• LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML  Journal Articles
• Leukemia targeting ligands isolated from phage display peptide libraries  Journal Articles
• Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer  Journal Articles
• Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs  Journal Articles
• Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo  Journal Articles
• Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis  Journal Articles
• Mathematical model for the cancer stem cell hypothesis  Journal Articles
• Medulloblastoma stem cells: Modeling tumor heterogeneity  Journal Articles
• Medulloblastoma stem cells: where development and cancer cross pathways  Journal Articles
• Metformin: Metabolic Rewiring Faces Tumor Heterogeneity  Journal Articles
• MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia  Journal Articles
• MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway  Journal Articles
• Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells  Journal Articles
• Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells  Journal Articles
• Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney  Journal Articles
• Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents  Journal Articles
• Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells  Journal Articles
• Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer  Journal Articles
• Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs  Journal Articles
• Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype  Journal Articles
• Oxymatrine diminishes the side population and inhibits the expression of β-catenin in MCF-7 breast cancer cells  Journal Articles
• PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer  Journal Articles
• Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions  Journal Articles
• Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells  Journal Articles
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Journal Articles
• Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma  Journal Articles
• Preclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer  Journal Articles
• Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting  Journal Articles
• Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation  Journal Articles
• Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response  Journal Articles
• Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells  Journal Articles
• RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity  Journal Articles
• Recent advances in Barrett's esophagus  Journal Articles
• Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells  Journal Articles
• Revealed: The spy who regulates neuroblastoma stem cells  Journal Articles
• Role of the tissue factor pathway in the biology of tumor initiating cells  Journal Articles
• SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells  Journal Articles
• Sam68 Allows Selective Targeting of Human Cancer Stem Cells  Journal Articles
• Scale-Up of Breast Cancer Stem Cell Aggregate Cultures to Suspension Bioreactors  Journal Articles
• Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts  Journal Articles
• Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer  Journal Articles
• Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer  Journal Articles
• Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models.  Journal Articles
• Stem cell gene expression programs influence clinical outcome in human leukemia  Journal Articles
• TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem–Like Cells in a Redox-Sensitive Manner  Journal Articles
• Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics  Journal Articles
• Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs  Journal Articles
• The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma  Journal Articles
• The Role of Serotonin in Breast Cancer Stem Cells  Journal Articles
• The identification of human pituitary adenoma-initiating cells  Journal Articles
• The role of stem cells in pediatric central nervous system malignancies.  Journal Articles
• The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression  Journal Articles
• The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells  Journal Articles
• The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors  Journal Articles
• USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation  Journal Articles
• Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML  Journal Articles
• Upregulation of FAM84B during prostate cancer progression  Journal Articles
• WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma  Journal Articles
• WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells  Journal Articles
• Yin-yang Balance Therapy on Regulating Cancer Stem Cells  Journal Articles
• [Tumor stem cells may be the final target of traditional Chinese medicine in preventing cancer recurrence and metastasis].  Journal Articles