subject area of
- A Cancer Stem Cell Model for Studying Brain Metastases From Primary Lung Cancer Journal Articles
- A Patient-Derived Xenograft Model of Glioblastoma Journal Articles
- A novel stem cell culture model of recurrent glioblastoma Journal Articles
- A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia Journal Articles
- A role for GPx3 in activity of normal and leukemia stem cells Journal Articles
- Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients Journal Articles
- Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity Journal Articles
- Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis Journal Articles
- Amplification of MUC1 in prostate cancer metastasis and CRPC development Journal Articles
- Antagonists of the serotonin receptor 5A target human breast tumor initiating cells Journal Articles
- Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2 Journal Articles
- BMI1 is a therapeutic target in recurrent medulloblastoma Conferences
- BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ Journal Articles
- Biting into a union of oncology and metabolism through leukemic stem cells Journal Articles
- Bmi1 marks intermediate precursors during differentiation of human brain tumor initiating cells Journal Articles
- Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells Journal Articles
- Brain Metastasis-Initiating Cells: Survival of the Fittest Journal Articles
- Breast cancer stem-like cells can promote metastasis by activating platelets and down-regulating antitumor activity of natural killer cells Journal Articles
- CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence Journal Articles
- Cancer Gastric Chemoprevention: Isolation of Gastric Tumor-Initiating Cells Journal Articles
- Cancer Stem Cells: Current Challenges and Future Perspectives Chapters
- Cancer stem cells in nervous system tumors Journal Articles
- Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations Journal Articles
- Characterization of brain cancer stem cells: a mathematical approach Journal Articles
- Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells Journal Articles
- Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma Conferences
- Childhood Medulloblastoma: An Overview Chapters
- Clinical–pathologic significance of cancer stem cell marker expression in familial breast cancers Journal Articles
- Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors Journal Articles
- Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations Journal Articles
- Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway Journal Articles
- Concepts of human leukemic development Journal Articles
- Contribution of Host-Derived Tissue Factor to Tumor Neovascularization Journal Articles
- Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma Journal Articles
- Culture and Isolation of Brain Tumor Initiating Cells Journal Articles
- Culture and Isolation of Brain Tumor Initiating Cells Journal Articles
- Cytokine treatment or accessory cells are required to initiate engraftment of purified primitive human hematopoietic cells transplanted at limiting doses into NOD/SCID mice Journal Articles
- Development of a Patient-Derived Xenograft Model Using Brain Tumor Stem Cell Systems to Study Cancer Journal Articles
- Differentiation of Brain Tumor Initiating Cells Chapters
- Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance Journal Articles
- Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma Journal Articles
- EMT: Mechanisms and therapeutic implications Journal Articles
- EPH Profiling of BTIC Populations in Glioblastoma Multiforme Using CyTOF Journal Articles
- Elevated tissue factor procoagulant activity in CD133‐positive cancer cells Journal Articles
- Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia Journal Articles
- Estrogen receptor of breast cancer stem cells depending on the original breast cancers Journal Articles
- Evidence for the transmission of neoplastic properties from transformed to normal human stem cells Journal Articles
- Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion Journal Articles
- Flow Cytometric Analysis of Brain Tumor Stem Cells Chapters
- FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Journal Articles
- From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration Journal Articles
- GBM secretome induces transient transformation of human neural precursor cells Journal Articles
- Gamma-secretase inhibitors target tumor-initiating cells in a mouse model of ERBB2 breast cancer Journal Articles
- Generation of Murine Xenograft Models of Brain Tumors from Primary Human Tissue for In Vivo Analysis of the Brain Tumor-Initiating Cell Journal Articles
- Guanosine-induced decrease in side population of lung cancer cells: lack of correlation with ABCG2 expression. Journal Articles
- Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells Journal Articles
- Identification of T-lymphocytic leukemia–initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease Journal Articles
- Identification of a cancer stem cell in human brain tumors. Journal Articles
- In Vitro Self-Renewal Assays for Brain Tumor Stem Cells Chapters
- Introduction to Brain Tumor Stem Cells Chapters
- Introduction to Cancer Stem Cells: Past, Present, and Future Chapters
- LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML Journal Articles
- Leukemia targeting ligands isolated from phage display peptide libraries Journal Articles
- Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer Journal Articles
- Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs Journal Articles
- Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo Journal Articles
- Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis Journal Articles
- Mathematical model for the cancer stem cell hypothesis Journal Articles
- Medulloblastoma stem cells: Modeling tumor heterogeneity Journal Articles
- Medulloblastoma stem cells: where development and cancer cross pathways Journal Articles
- Metformin: Metabolic Rewiring Faces Tumor Heterogeneity Journal Articles
- MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia Journal Articles
- MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway Journal Articles
- Molecular Pathways: Epigenetic Modulation of Wnt–Glycogen Synthase Kinase-3 Signaling to Target Human Cancer Stem Cells Journal Articles
- Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells Journal Articles
- Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney Journal Articles
- Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents Journal Articles
- Neoplastic human embryonic stem cells as a model of radiation resistance of human cancer stem cells Journal Articles
- Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer Journal Articles
- Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs Journal Articles
- Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype Journal Articles
- Oxymatrine diminishes the side population and inhibits the expression of β-catenin in MCF-7 breast cancer cells Journal Articles
- PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer Journal Articles
- Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions Journal Articles
- Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells Journal Articles
- Pluripotent human stem cell lines: what we can learn about cancer initiation Journal Articles
- Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma Journal Articles
- Processing of Primary Brain Tumor Tissue for Stem Cell Assays and Flow Sorting Journal Articles
- Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation Journal Articles
- Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response Journal Articles
- Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells Journal Articles
- RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity Journal Articles
- Recent advances in Barrett's esophagus Journal Articles
- Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells Journal Articles
- Revealed: The spy who regulates neuroblastoma stem cells Journal Articles
- Role of the tissue factor pathway in the biology of tumor initiating cells Journal Articles
- SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells Journal Articles
- Sam68 Allows Selective Targeting of Human Cancer Stem Cells Journal Articles
- Scale-Up of Breast Cancer Stem Cell Aggregate Cultures to Suspension Bioreactors Journal Articles
- Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts Journal Articles
- Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer Journal Articles
- Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer Journal Articles
- Stem cell gene expression programs influence clinical outcome in human leukemia Journal Articles
- TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem–Like Cells in a Redox-Sensitive Manner Journal Articles
- Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics Journal Articles
- The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma Journal Articles
- The Role of Serotonin in Breast Cancer Stem Cells Journal Articles
- The identification of human pituitary adenoma-initiating cells Journal Articles
- The role of stem cells in pediatric central nervous system malignancies. Journal Articles
- The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression Journal Articles
- The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells Journal Articles
- The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors Journal Articles
- USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation Journal Articles
- Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML Journal Articles
- Upregulation of FAM84B during prostate cancer progression Journal Articles
- WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma Journal Articles
- Yin-yang Balance Therapy on Regulating Cancer Stem Cells Journal Articles
- [Tumor stem cells may be the final target of traditional Chinese medicine in preventing cancer recurrence and metastasis]. Journal Articles