Estrogen receptor of breast cancer stem cells depending on the original breast cancers
Academic Article
Overview
Research
Identity
Additional Document Info
View All
Overview
abstract
There has been arguments about the estrogen receptor-α (from this point referred to as ER) of breast cancer stem cells (BrCSCs). Most investigations support the proposition that BrCSCs are ER(-), whereas some other studies indicate that BrCSCs are ER(+). We concluded that the ER expression of BrCSCs in ER(+) breast cancers is positive, while it is negative in ER(-) breast cancers. Therefore, we hypothesize that the ER expression of BrCSCs depends on the original breast cancers. It may provide a novel strategy for the therapy targeting BrCSCs.
