Journal article
Oxymatrine diminishes the side population and inhibits the expression of β-catenin in MCF-7 breast cancer cells
Abstract
Cancer stem cells (CSCs) play a critical role in both cancer initiation and relapse as they are resistant to most cytotoxic agents and able to proliferate indefinitely. The plant alkaloid oxymatrine has many biological activities including the ability to induce cell cycle arrest and apoptosis, which makes it a potentially useful agent for targeting cancer cells. In order to determine whether it has beneficial pharmacological properties to …
Authors
Zhang Y; Piao B; Zhang Y; Hua B; Hou W; Xu W; Qi X; Zhu X; Pei Y; Lin H
Journal
Medical Oncology, Vol. 28, No. Suppl 1, pp. 99–107
Publisher
Springer Nature
Publication Date
December 2011
DOI
10.1007/s12032-010-9721-y
ISSN
1357-0560