Intracellular Signaling Peptides and Proteins Concept

subject area of

• 5-(Perylen-3-yl)Ethynyl-arabino-Uridine (aUY11), an Arabino-Based Rigid Amphipathic Fusion Inhibitor, Targets Virion Envelope Lipids To Inhibit Fusion of Influenza Virus, Hepatitis C Virus, and Other Enveloped Viruses  Academic Article
• A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells  Academic Article
• A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia  Academic Article
• Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4Rgenes to obesity in Mexican children  Academic Article
• Association analyses of the DAOA/G30 and d-amino-acid oxidase genes in schizophrenia: Further evidence for a role in schizophrenia  Academic Article
• Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse  Academic Article
• Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex  Academic Article
• Characterizing synaptic protein development in human visual cortex enables alignment of synaptic age with rat visual cortex  Academic Article
• Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy  Academic Article
• Cholesterol Interaction with Proteins That Partition into Membrane Domains: An Overview  Academic Article
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Academic Article
• Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"  Academic Article
• Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"  Academic Article
• Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity"  Academic Article
• Comparing development of synaptic proteins in rat visual, somatosensory, and frontal cortex  Academic Article
• Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies  Academic Article
• DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants  Academic Article
• Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid  Academic Article
• Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells  Academic Article
• Determination of soluble CAMP-dependent protein kinase activity in guinea-pig tracheal smooth muscle  Academic Article
• Development of Glutamatergic Proteins in Human Visual Cortex across the Lifespan  Academic Article
• Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development  Academic Article
• Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old  Academic Article
• Evolution of the chaperonin families (HSP60, HSP 10 and TCP-1) of proteins and the origin of eukaryotic cells  Academic Article
• Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase  Academic Article
• Expression of xCT and activity of system xc− are regulated by NRF2 in human breast cancer cells in response to oxidative stress  Academic Article
• Fine Mapping of the Insulin-Induced Gene 2 Identifies a Variant Associated With LDL Cholesterol and Total Apolipoprotein B Levels  Academic Article
• Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression  Academic Article
• Functional dynamics in cyclic nucleotide signaling and amyloid inhibition  Academic Article
• Gene expression profiling in human skeletal muscle during recovery from eccentric exercise  Academic Article
• Genetic determinants of plasma triglycerides  Academic Article
• Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci  Academic Article
• Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations  Academic Article
• High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists  Academic Article
• Homocysteine-Induced Endoplasmic Reticulum Stress and Growth Arrest Leads to Specific Changes in Gene Expression in Human Vascular Endothelial Cells  Academic Article
• Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells  Academic Article
• Identification of genetic variants associated with susceptibility to West Nile virus neuroinvasive disease  Academic Article
• Induction of raft-like domains by a myristoylated NAP-22 peptide and its Tyr mutant  Academic Article
• Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions  Academic Article
• Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling  Academic Article
• KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase  Academic Article
• Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development  Academic Article
• Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats  Academic Article
• Light and COP1 regulate level of overexpressed DET1 protein  Academic Article
• Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation  Academic Article
• Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?  Academic Article
• Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR  Academic Article
• Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit  Academic Article
• Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles  Academic Article
• NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance  Academic Article
• NSD1 mutations generate a genome-wide DNA methylation signature  Academic Article
• Orexins/Hypocretins Act in the Posterior Paraventricular Thalamic Nucleus During Repeated Stress to Regulate Facilitation to Novel Stress  Academic Article
• Oxidative stress and Nrf2 signaling in McArdle disease  Academic Article
• PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle  Academic Article
• PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice  Academic Article
• Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo  Academic Article
• Phenotypic variability of CMT4C in a French-Canadian kindred  Academic Article
• Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation  Academic Article
• Plasmodesmata-located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long-distance movement of Defective in Induced Resistance1 inArabidopsis  Academic Article
• Polygenic determinants of severe hypertriglyceridemia  Academic Article
• Proteomic Analysis Reveals Autism-Associated Gene DIXDC1 Regulates Proteins Associated with Mitochondrial Organization and Function  Academic Article
• RYBP Is a K63-Ubiquitin-Chain-Binding Protein that Inhibits Homologous Recombination Repair  Academic Article
• Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial  Academic Article
• Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor  Academic Article
• Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2  Academic Article
• Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca²⁺]_i  Academic Article
• Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli.  Academic Article
• Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells  Academic Article
• Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men  Academic Article
• S100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situof the breast  Academic Article
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Academic Article
• SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells  Academic Article
• Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins.  Academic Article
• Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann–Pick disease type C1  Academic Article
• Socs1 Deficiency Enhances Hepatic Insulin Signaling  Academic Article
• TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation  Academic Article
• The Extending Spectrum of NPC1-Related Human Disorders: From Niemann–Pick C1 Disease to Obesity  Academic Article
• The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’  Academic Article
• The Niemann-Pick C1 gene interacts with a high-fat diet to promote weight gain through differential regulation of central energy metabolism pathways  Academic Article
• The Relative Biological Effectiveness of Low-Dose Mammography Quality X Rays in the Human Breast MCF-10A Cell Line  Academic Article
• The defining DNA methylation signature of Floating-Harbor Syndrome  Academic Article
• The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells  Academic Article
• Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia  Academic Article
• Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis  Academic Article
• Variants of theorexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity  Academic Article
• Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles  Academic Article
• Voluntary physical activity and leucine correct impairments in muscle protein synthesis in partially pancreatectomised rats  Academic Article
• Whole-exome sequencing is a valuable diagnostic tool for inherited peripheral neuropathies: Outcomes from a cohort of 50 families  Academic Article
• YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer  Academic Article
• β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis  Academic Article