Intracellular Signaling Peptides and Proteins Concept

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A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells Journal Articles
A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia Journal Articles
Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish Journal Articles
Association analyses of the DAOA/G30 and d-amino-acid oxidase genes in schizophrenia: Further evidence for a role in schizophrenia Journal Articles
Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse Journal Articles
Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex Journal Articles
Characterizing synaptic protein development in human visual cortex enables alignment of synaptic age with rat visual cortex Journal Articles
Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy Journal Articles
Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins Journal Articles
Comparing development of synaptic proteins in rat visual, somatosensory, and frontal cortex Journal Articles
Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies Journal Articles
DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants Journal Articles
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid Journal Articles
Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells Journal Articles
Determination of soluble CAMP-dependent protein kinase activity in guinea-pig tracheal smooth muscle Journal Articles
Development of Glutamatergic Proteins in Human Visual Cortex across the Lifespan Journal Articles
Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development Journal Articles
Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old Journal Articles
Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses. Journal Articles
Evolution of the chaperonin families (HSP60, HSP 10 and TCP‐1) of proteins and the origin of eukaryotic cells Journal Articles
Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase Journal Articles
Expression of xCT and activity of system xc− are regulated by NRF2 in human breast cancer cells in response to oxidative stress Journal Articles
Fine Mapping of the Insulin-Induced Gene 2 Identifies a Variant Associated With LDL Cholesterol and Total Apolipoprotein B Levels Journal Articles
Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression Journal Articles
Functional dynamics in cyclic nucleotide signaling and amyloid inhibition Journal Articles
Gene expression profiling in human skeletal muscle during recovery from eccentric exercise Journal Articles
Genetic determinants of plasma triglycerides Journal Articles
Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci Journal Articles
HSD17B6 delays type 2 diabetes development via inhibiting SREBP activation Journal Articles
High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists Journal Articles
Homocysteine-Induced Endoplasmic Reticulum Stress and Growth Arrest Leads to Specific Changes in Gene Expression in Human Vascular Endothelial Cells Journal Articles
Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells Journal Articles
Identification of genetic variants associated with susceptibility to West Nile virus neuroinvasive disease Journal Articles
Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling Journal Articles
KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase Journal Articles
Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development Journal Articles
Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats Journal Articles
Light and COP1 regulate level of overexpressed DET1 protein Journal Articles
Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation Journal Articles
Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle. Journal Articles
Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design? Journal Articles
Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR Journal Articles
Modulation of autophagy signaling with resistance exercise and protein ingestion following short-term energy deficit Journal Articles
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles Journal Articles
NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance Journal Articles
NSD1 mutations generate a genome-wide DNA methylation signature Journal Articles
Orexins/Hypocretins Act in the Posterior Paraventricular Thalamic Nucleus During Repeated Stress to Regulate Facilitation to Novel Stress Journal Articles
Oxidative stress and Nrf2 signaling in McArdle disease Journal Articles
PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle Journal Articles
PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice Journal Articles
Parkinson-susceptibility gene DJ-1/PARK7 protects the murine heart from oxidative damage in vivo Journal Articles
Phenotypic variability of CMT4C in a French‐Canadian kindred Journal Articles
Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation Journal Articles
Plasmodesmata‐located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long‐distance movement of Defective in Induced Resistance1 in Arabidopsis Journal Articles
Polygenic determinants of severe hypertriglyceridemia Journal Articles
Proteomic Analysis Reveals Autism-Associated Gene DIXDC1 Regulates Proteins Associated with Mitochondrial Organization and Function Journal Articles
RYBP Is a K63-Ubiquitin-Chain-Binding Protein that Inhibits Homologous Recombination Repair Journal Articles
Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial Journal Articles
Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor Journal Articles
Regulation of Acidification and Apoptosis by SHP-1 and Bcl-2 Journal Articles
Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca²⁺]_i Journal Articles
Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli Journal Articles
Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Journal Articles
Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells Journal Articles
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers Journal Articles
Resistance exercise volume affects myofibrillar protein synthesis and anabolic signalling molecule phosphorylation in young men Journal Articles
Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance. Journal Articles
S100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situof the breast Journal Articles
SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis Journal Articles
SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells Journal Articles
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP Journal Articles
Sequence and structural homology between a mouse T-complex protein TCP-1 and the 'chaperonin' family of bacterial (GroEL, 60-65 kDa heat shock antigen) and eukaryotic proteins. Journal Articles
Socs1 Deficiency Enhances Hepatic Insulin Signaling Journal Articles
TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradation Journal Articles
The Extending Spectrum of NPC1-Related Human Disorders: From Niemann–Pick C1 Disease to Obesity Journal Articles
The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’ Journal Articles
The Relative Biological Effectiveness of Low-Dose Mammography Quality X Rays in the Human Breast MCF-10A Cell Line Journal Articles
The defining DNA methylation signature of Floating-Harbor Syndrome Journal Articles
The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells Journal Articles
The role of the type I insulin-like growth factor receptor (IGF-IR) in glomerular integrity Journal Articles
Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia Journal Articles
Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis Journal Articles
Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity Journal Articles
Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Journal Articles
Voluntary physical activity and leucine correct impairments in muscle protein synthesis in partially pancreatectomised rats Journal Articles
WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells Journal Articles
Whole‐exome sequencing is a valuable diagnostic tool for inherited peripheral neuropathies: Outcomes from a cohort of 50 families Journal Articles
YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer Journal Articles
[Expressions of cytoprotective proteins for human renal allografts]. Journal Articles
β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis Journal Articles