Doxorubicin Concept

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• 5-Fluorouracil, Adriamycin, and Mitomycin-C (FAM) in the Treatment of Inoperable Adenocarcinoma of the Lung  Journal Articles
• A Comparison of Elderly Patients with Aggressive Histology Lymphoma who Were Entered or Not Entered on to a Randomized Phase II Trial  Journal Articles
• A Phase I Study of Pegylated Liposomal Doxorubicin Hydrochloride (Caelyx™) in Combination with Cyclophosphamide and Vincristine as Second-Line Treatment of Patients with Small-Cell Lung Cancer  Journal Articles
• A Phase I Trial of Standard and Cyclophosphamide Dose-Escalated CHOP with Granulocyte Colony Stimulating Factor in Elderly Patients with Non-Hodgkin's Lymphoma  Journal Articles
• A Prospective, non-randomised phase 1–2 trial of VACOP-B with filgrastim support for HIV-related non-Hodgkin's lymphoma  Journal Articles
• A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer  Journal Articles
• A phase II study of doxorubicin/paclitaxel plus G-CSF for metastatic breast cancer.  Journal Articles
• A phase I–II study of oblimersen sodium (G3139, Genasense) in combination with doxorubicin in advanced hepatocellular carcinoma (NCI # 5798)  Journal Articles
• A pilot study to investigate the feasibility and cardiac effects of pegylated liposomal doxorubicin (PL-DOX) as adjuvant therapy in medically fit elderly breast cancer patients  Journal Articles
• A population-based study of cardiac morbidity among Hodgkin lymphoma patients with preexisting heart disease  Journal Articles
• A predictive index of cure versus no cure in advanced ovarian carcinoma patients—Replacement of second-look laparotomy as a diagnostic test  Journal Articles
• A randomized trial comparing 12 weeks versus 36 weeks of adjuvant chemotherapy in stage II breast cancer.  Journal Articles
• A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma  Journal Articles
• A systematic meta‐analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft‐tissue sarcoma  Journal Articles
• ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma  Journal Articles
• Absence of Secondary Malignant Neoplasms in Children With High-Risk Acute Lymphoblastic Leukemia Treated With Dexrazoxane  Journal Articles
• Acute Cardiac Functional and Morphological Changes After Anthracycline Infusions in Children  Journal Articles
• Acute Perforative Appendicitis During Preoperative Chemotherapy for Wilms Tumor  Journal Articles
• Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer a phase I/II study  Journal Articles
• Adjuvant chemotherapy and timing of tamoxifen in postmenopausal patients with endocrine-responsive, node-positive breast cancer: a phase 3, open-label, randomised controlled trial  Journal Articles
• Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults  Journal Articles
• Adjuvant chemotherapy for localised resectable soft-tissue sarcoma of adults: meta-analysis of individual data  Journal Articles
• Adriamycin and cisplatin in the treatment of stage III and IV epithelial ovarian carcinoma  Journal Articles
• Alemtuzumab and CHOP Chemotherapy for the Treatment of Aggressive Histology Peripheral T Cell Lymphomas: A Multi-Center Phase I Study  Journal Articles
• An NCIC-CTG phase I dose escalation pharmacokinetic study of the matrix metalloproteinase inhibitor BAY 12-9566 in combination with doxorubicin  Journal Articles
• An individual patient-data comparison of combined modality therapy and ABVD alone for patients with limited-stage Hodgkin lymphoma  Journal Articles
• Analysis of dose intensity for chemotherapy in early (stage II) and advanced breast cancer.  Journal Articles
• Anthracycline Adjuvant Chemotherapy: How Much Is Enough?  Journal Articles
• Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression  Journal Articles
• Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial  Journal Articles
• Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial.  Journal Articles
• Assessment of myocardial fibrosis by endoventricular electromechanical mapping in experimental nonischemic cardiomyopathy  Journal Articles
• Autologous Transplantation as Consolidation for Aggressive Non-Hodgkin's Lymphoma  Journal Articles
• Bacterial Inactivation of the Anticancer Drug Doxorubicin  Journal Articles
• Balancing Risks and Benefits of Therapy for Patients with Favorable-Risk Limited-Stage Hodgkin Lymphoma  Journal Articles
• Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line  Journal Articles
• Breast cancer chemotherapy induces the release of cell‐free DNA, a novel procoagulant stimulus  Journal Articles
• Canadian multicenter randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung.  Journal Articles
• Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial  Journal Articles
• Cardiorespiratory status after treatment for acute lymphoblastic leukemia  Journal Articles
• Changes in Body Composition in Patients with Small-Cell Lung Cancer  Journal Articles
• Changes in Cardiac Biomarkers During Doxorubicin Treatment of Pediatric Patients With High-Risk Acute Lymphoblastic Leukemia: Associations With Long-Term Echocardiographic Outcomes  Conferences
• Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting  Journal Articles
• Chemotherapeutic agents doxorubicin and epirubicin induce a procoagulant phenotype on endothelial cells and blood monocytes  Conferences
• Chemotherapy agents and the induction of late lethal defects.  Journal Articles
• Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial.  Journal Articles
• Chemotherapy for metastatic transitional carcinoma of the urinary tract:A prospective trial of methotrexate, adriamycin, and cyclophosphamide (MAC) with cis-platinum for failure  Journal Articles
• Chemotherapy of advanced ovarian carcinoma: Initial experience using a platinum-based combination  Journal Articles
• Chemotherapy waste reduction through shelf-life extension.  Journal Articles
• Childhood Atypical Teratoid Rhabdoid Tumor of the Central Nervous System  Journal Articles
• Combination chemotherapy and alpha-interferon in the treatment of Kaposi's sarcoma associated with acquired immune deficiency syndrome.  Journal Articles
• Combined Modality Treatment of Small Cell Carcinoma of the Lung  Journal Articles
• Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.  Journal Articles
• Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes  Journal Articles
• Cost-effectiveness of cancer chemotherapy: an economic evaluation of a randomized trial in small-cell lung cancer.  Journal Articles
• Cross-resistance to intercalating agents in an epipodophyllotoxin-resistant Chinese hamster ovary cell line: evidence for a common intracellular target.  Journal Articles
• Current approaches to the treatment of advanced-stage Hodgkin's disease.  Journal Articles
• Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: superiority of doxorubicin.  Journal Articles
• Cyclophosphamide, Epirubicin, and Fluorouracil Versus Dose-Dense Epirubicin and Cyclophosphamide Followed by Paclitaxel Versus Doxorubicin and Cyclophosphamide Followed by Paclitaxel in Node-Positive or High-Risk Node-Negative Breast Cancer  Journal Articles
• Cyclophosphamide, doxorubicin, and cisplatin in the treatment of non-small cell bronchogenic carcinoma.  Journal Articles
• Cyclophosphamide, doxorubicin, and vincristine in etoposide- and cisplatin-resistant small cell lung cancer.  Journal Articles
• Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid), polysorbate 80 and starch for delivery of doxorubicin  Journal Articles
• Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues  Journal Articles
• Disulfide-Cross-Linked Nanogel-Based Nanoassemblies for Chemotherapeutic Drug Delivery  Journal Articles
• Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer  Journal Articles
• Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol.  Journal Articles
• Durable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV-8-positive, HIV-negative patient  Journal Articles
• Effect of adjuvant central iv hyperalimentation on the survival and response to treatment of patients with small cell lung cancer: a randomized trial.  Journal Articles
• Effect of the addition of rituximab to salvage chemotherapy prior to autologous stem cell transplant in aggressive CD20+ lymphoma: a cohort comparison from the NCIC Clinical Trials Group Study LY.12^*  Journal Articles
• Effectiveness of antibacterial prophylaxis during induction chemotherapy in children with acute lymphoblastic leukemia  Journal Articles
• Effects of a treatment gap during adjuvant chemotherapy in node-positive breast cancer: results of International Breast Cancer Study Group (IBCSG) Trials 13-93 and 14-93  Journal Articles
• Effects of intravenous hyperalimentation during treatment in patients with small-cell lung cancer.  Journal Articles
• Effects of the chemotherapeutic agent doxorubicin on the protein C anticoagulant pathway  Journal Articles
• Effects of total parenteral nutrition and chemotherapy on the metabolic derangements in small cell lung cancer.  Journal Articles
• Eight Cycles of ABVD Versus Four Cycles of BEACOPP_escalatedPlus Four Cycles of BEACOPP_baselinein Stage III to IV, International Prognostic Score ≥ 3, High-Risk Hodgkin Lymphoma: First Results of the Phase III EORTC 20012 Intergroup Trial  Journal Articles
• Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors  Journal Articles
• Escalated as Compared with Standard Doses of Doxorubicin in BACOP Therapy for Patients with Non-Hodgkin's Lymphoma  Journal Articles
• Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.  Journal Articles
• Exploring the mechanism of cordycepin combined with doxorubicin in treating glioblastoma based on network pharmacology and biological verification.  Journal Articles
• First line therapy with paclitaxel (Taxol®) and pegylated liposomal doxorubicin (Caelyx®) in patients with metastatic breast cancer: a multicentre phase II study  Journal Articles
• Flavopiridol Sensitivity of Cancer Cells Isolated from Ascites and Pleural Fluids  Journal Articles
• Gadopentatic acid affects in vitro proliferation and doxorubicin response in human breast adenocarcinoma cells  Journal Articles
• Genomic and Genic Deletions of the FOX Gene Cluster on 16q24.1 and Inactivating Mutations of FOXF1 Cause Alveolar Capillary Dysplasia and Other Malformations  Journal Articles
• HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner  Journal Articles
• Hair Regrowth after Cancer Therapy  Journal Articles
• Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6  Journal Articles
• Hepatic arterial infusion of mitoxantrone in the treatment of primary hepatocellular carcinoma.  Journal Articles
• Hepatitis B, Rituximab, Screening, and Prophylaxis: Effectiveness and Cost Effectiveness  Journal Articles
• Herpes zoster in patients with carcinoma of the lung  Journal Articles
• High dose doxorubicin plus cisplatin in the treatment of unresectable mesotheliomas: report of four cases  Journal Articles
• Impact of Chemotherapy on Thrombin Generation and on the Protein C Pathway in Breast Cancer Patients  Journal Articles
• Impact of hemochromatosis gene mutations on cardiac status in doxorubicin‐treated survivors of childhood high‐risk leukemia  Journal Articles
• Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01  Journal Articles
• Inconsistency of prognostic factors for post-chemotherapy nausea and vomiting  Journal Articles
• Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin  Journal Articles
• Infusional Chemotherapy for Non-Hodgkin's Lymphoma  Journal Articles
• Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain  Journal Articles
• Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells  Journal Articles
• Investigating and addressing the immediate and long-term consequences of the COVID-19 pandemic on patients with substance use disorders: a scoping review and evidence map protocol  Journal Articles
• Is there convincing evidence for the use of chemotherapy alone in patients with limited stage Hodgkin's lymphoma?  Journal Articles
• Left and right ventricular effects of anthracycline and trastuzumab chemotherapy: A prospective study using novel cardiac imaging and biochemical markers  Journal Articles
• Liver-on-a-Chip Integrated with Label-Free Optical Biosensors for Rapid and Continuous Monitoring of Drug-Induced Toxicity.  Journal Articles
• Long-term outcome of a pediatric-inspired regimen used for adults aged 18–50 years with newly diagnosed acute lymphoblastic leukemia  Journal Articles
• Management of Children with Acute Lymphoblastic Leukemia by the Dana-Farber Cancer Institute Protocols  Journal Articles
• MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function  Journal Articles
• Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II  Journal Articles
• Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression  Journal Articles
• NR1D1 Recruitment to Sites of DNA Damage Inhibits Repair and Is Associated with Chemosensitivity of Breast Cancer  Journal Articles
• Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents  Journal Articles
• Non-radioactive 2-deoxy-2-fluoro-D-glucose inhibits glucose uptake in xenograft tumours and sensitizes HeLa cells to doxorubicin in vitro  Journal Articles
• Optimal pathological response after neoadjuvant chemotherapy for muscle‐invasive bladder cancer: results from a global, multicentre collaboration  Journal Articles
• Osteopenia in children with acute lymphoblastic leukemia: A pilot study of amelioration with pamidronate  Journal Articles
• Outcomes of MYC‐associated lymphomas after R‐CHOP with and without consolidative autologous stem cell transplant: subset analysis of randomized trial intergroup SWOG S9704  Journal Articles
• Outcomes of Patients Treated With RCHOP With a PET-Adapted Approach for Consolidative Radiotherapy: A Retrospective Single-Center Study at the Royal Marsden Hospital  Journal Articles
• Outcomes of treatment with CHOP and EPOCH in patients with HIV associated NHL in a low resource setting  Journal Articles
• Ovarian cancer in elderly patients: carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in late relapse: a Gynecologic Cancer Intergroup (GCIG) CALYPSO sub-study  Journal Articles
• Paraspinal Synovial Sarcoma as an Unusual Postradiation Complication in Pediatric Abdominal Neuroblastoma  Journal Articles
• Patterns of disease progression and outcomes in a randomized trial testing ABVD alone for patients with limited-stage Hodgkin lymphoma  Journal Articles
• Pegylated Liposomal Doxorubicin and Trastuzumab in HER-2 Overexpressing Metastatic Breast Cancer: A Multicenter Phase II Trial  Conferences
• Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98)  Journal Articles
• Phase I trial of gemcitabine, doxorubicin and cisplatin (GAP) in patients with advanced solid tumors  Journal Articles
• Phase II Trial of N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine.HCl and Doxorubicin Chemotherapy in Metastatic Breast Cancer: A National Cancer Institute of Canada Clinical Trials Group Study  Journal Articles
• Phase II multicenter open-label study of carboplatin and pegylated liposomal doxorubicin in uterine and cervical malignancies  Conferences
• Phase II study of pegylated liposomal doxorubicin HCl (Caelyx) in combination with cyclophosphamide and vincristine as second-line treatment of patients with small cell lung cancer  Journal Articles
• Preferential Killing of Breast Tumor Initiating Cells by N,N-Diethyl-2-[4-(Phenylmethyl)Phenoxy]Ethanamine/Tesmilifene  Journal Articles
• Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial  Journal Articles
• Pure red cell aplasia complicating B cell small lymphocytic lymphoma: a case report  Journal Articles
• Radiation in early-stage Hodgkin lymphoma.  Journal Articles
• Radionuclide angiography and endomyocardial biopsy in the assessment of doxorubicin cardiotoxicity  Journal Articles
• Radiotherapy to control CNS lymphomatoid granulomatosis: A case report and review of the literature  Journal Articles
• Randomized Comparison of ABVD Chemotherapy With a Strategy That Includes Radiation Therapy in Patients With Limited-Stage Hodgkin’s Lymphoma: National Cancer Institute of Canada Clinical Trials Group and the Eastern Cooperative Oncology Group  Journal Articles
• Randomized Trial of High-Dose Chemotherapy With Autologous Peripheral-Blood Stem-Cell Support Compared With Standard-Dose Chemotherapy in Women With Metastatic Breast Cancer: NCIC MA.16  Journal Articles
• Randomized phase II comparison of standard CHOP with weekly CHOP in elderly patients with non-Hodgkin's lymphoma.  Journal Articles
• Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers  Journal Articles
• Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia  Journal Articles
• Reversal of hypertrophic osteoarthropathy after chemotherapy for bronchogenic carcinoma.  Journal Articles
• Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown  Journal Articles
• Ribbon of DNA Lattice on Gold Nanoparticles for Selective Drug Delivery to Cancer Cells  Journal Articles
• S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation  Journal Articles
• Second-line chemotherapy of stage III-IV ovarian carcinoma: a randomized comparison of melphalan to melphalan and hexamethylmelamine in patients with persistent disease after doxorubicin and cisplatin.  Journal Articles
• Soft-tissue injury caused by antineoplastic drugs is inhibited by topical dimethyl sulphoxide and alpha tocopherol  Journal Articles
• Soft-tissue necrosis induced by extravasated cancer chemotherapeutic agents: A study of active intervention  Journal Articles
• Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature  Journal Articles
• Strain Rate Imaging Detects Early Cardiac Effects of Pegylated Liposomal Doxorubicin as Adjuvant Therapy in Elderly Patients with Breast Cancer  Journal Articles
• Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer  Journal Articles
• Supramolecularly-Cross-Linked Nanogel Assemblies for On-Demand, Ultrasound-Triggered Chemotherapy  Journal Articles
• Surgical treatment for limited small-cell lung cancer  Journal Articles
• The Effect of Dexrazoxane on Myocardial Injury in Doxorubicin-Treated Children with Acute Lymphoblastic Leukemia  Journal Articles
• The Feasibility of Adjuvant Surgery in Limited-Stage Small Cell Carcinoma: A Prospective Evaluation  Journal Articles
• The Thrombogenic Effect of Anticancer Drug Therapy in Women with Stage II Breast Cancer  Journal Articles
• The Transcriptional Coactivator Yes-Associated Protein Drives p73 Gene-Target Specificity in Response to DNA Damage  Journal Articles
• The chemotherapy of granulosa cell tumors of the ovary: Experience of the wisconsin clinical cancer center  Journal Articles
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Journal Articles
• The effect of dose of thoracic irradiation on recurrence in patients with limited stage small cell lung cancer. Initial results of a canadian multicenter randomized trial  Journal Articles
• The effect of systemic adjuvant chemotherapy on local breast recurrence in node positive breast cancer patients treated by lumpectomy without radiation  Journal Articles
• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces  Journal Articles
• The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors  Journal Articles
• The treatment of acute myelocytic leukemia in patients 30 years of age and younger  Journal Articles
• The use of VP-16 plus cisplatin during induction chemotherapy for small-cell lung cancer.  Journal Articles
• Transformation of the Anticancer Drug Doxorubicin in the Human Gut Microbiome  Journal Articles
• Treatment Strategies in Elderly Patients with Aggressive Histology Lymphoma  Journal Articles
• Treatment of Hodgkin lymphoma with adriamycin, bleomycin, vinblastine and dacarbazine without routine granulocyte-colony stimulating factor support does not increase the risk of febrile neutropenia: a prospective cohort study  Journal Articles
• Treatment of Small Cell Lung Cancer in the Elderly  Journal Articles
• Treatment of advanced Hodgkin's disease with chemotherapy--comparison of MOPP/ABV hybrid regimen with alternating courses of MOPP and ABVD: a report from the National Cancer Institute of Canada clinical trials group.  Journal Articles
• Treatment of patients with acute nonlymphocytic leukemia in relapse: A leukemia intergroup study  Journal Articles
• Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B, type I-dependent manner  Journal Articles
• Upper half body irradiation (UHBI) for extensive small cell carcinoma of the lung  Journal Articles
• Use and Misuse of Waterfall Plots  Journal Articles
• Use of Molecular Biomarkers to Quantify the Spatial Distribution of Effects of Anticancer Drugs in Solid Tumors  Journal Articles
• Use of granulocyte colony-stimulating factor (G-CSF) in patients receiving myelosuppressive chemotherapy for the treatment of cancer. Provincial Systemic Treatment Disease Site Group.  Journal Articles
• Use of the Proton Pump Inhibitor Pantoprazole to Modify the Distribution and Activity of Doxorubicin: A Potential Strategy to Improve the Therapy of Solid Tumors  Journal Articles
• What drives requests for MAiD?  Journal Articles
• p53: The pivot between cell cycle arrest and senescence  Journal Articles
• pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells  Journal Articles