Journal article
Effectiveness of antibacterial prophylaxis during induction chemotherapy in children with acute lymphoblastic leukemia
Abstract
BACKGROUND: Pediatric patients receiving induction chemotherapy for newly diagnosed acute lymphoblastic leukemia (ALL) are at high risk of developing life-threatening infections. We investigated whether uniform antibacterial guidelines, including mandatory antibacterial prophylaxis in afebrile patients during induction, decreases the incidence of microbiologically documented bacteremia.
METHODS: Between 2012 and 2015, 230 patients with newly …
Authors
Sulis ML; Blonquist TM; Stevenson KE; Hunt SK; Kay‐Green S; Athale UH; Clavell LA; Cole PD; Kelly KM; Laverdiere C
Journal
Pediatric Blood & Cancer, Vol. 65, No. 5,
Publisher
Wiley
Publication Date
May 2018
DOI
10.1002/pbc.26952
ISSN
1545-5009
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAntibiotic ProphylaxisAntineoplastic Combined Chemotherapy ProtocolsAsparaginaseBacteremiaChildChild, PreschoolDoxorubicinFemaleFollow-Up StudiesHumansInduction ChemotherapyInfantMaleMethotrexatePolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaPrednisonePrognosisSurvival RateVincristineYoung Adult