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Absence of Secondary Malignant Neoplasms in...
Journal article

Absence of Secondary Malignant Neoplasms in Children With High-Risk Acute Lymphoblastic Leukemia Treated With Dexrazoxane

Abstract

PURPOSE: Dexrazoxane is a drug used to prevent anthracycline-induced cardiotoxicity. A recent report found an association between the use of dexrazoxane and the risk of developing secondary malignant neoplasms (SMNs) in children with Hodgkin's disease. We report the absence of an association of SMNs in children with acute lymphoblastic leukemia (ALL) treated on Dana-Farber Cancer Institute ALL Consortium Protocol 95-01. PATIENTS AND METHODS: …

Authors

Barry EV; Vrooman LM; Dahlberg SE; Neuberg DS; Asselin BL; Athale UH; Clavell LA; Larsen EC; Moghrabi A; Samson Y

Journal

Journal of Clinical Oncology, Vol. 26, No. 7, pp. 1106–1111

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

March 1, 2008

DOI

10.1200/jco.2007.12.2481

ISSN

0732-183X