Journal article
Use and Misuse of Waterfall Plots
Abstract
BACKGROUND: "Waterfall plots" are used to describe changes in tumor size observed in clinical studies. Here we assess criteria for generation of waterfall plots and the impact of measurement error in generating them.
METHODS: We reviewed published waterfall plots to investigate variability in criteria used to define them. We then compared waterfall plots generated by different observers for 24 patients enrolled in a completed phase I study of …
Authors
Shao T; Wang L; Templeton AJ; Jang R; Vera-Badillo FW; McNamara MG; Margolis M; Kim TK; Sinaei M; Shoushtari H
Journal
Journal of the National Cancer Institute, Vol. 106, No. 12,
Publisher
Oxford University Press (OUP)
Publication Date
December 1, 2014
DOI
10.1093/jnci/dju331
ISSN
0027-8874