Cyclic AMP Concept

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• 8-isoprostaglandin E2 activates Ca2+-dependent K+ current via cyclic AMP signaling pathway in murine renal artery  Academic Article
• A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP  Academic Article
• A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain  Academic Article
• A Review of Candidate Pathways Underlying the Association Between Asthma and Major Depressive Disorder  Academic Article
• A simple mathematical model of second-messenger mediated slow excitatory postsynaptic potentials.  Academic Article
• Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise  Academic Article
• Allosteric linkers in cAMP signalling  Academic Article
• Arachidonic Acid and Prostaglandin E2 Stimulate Testosterone Production by Goldfish Testis in Vitro  Academic Article
• Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.  Academic Article
• Beta-adrenoceptors in human lung, bronchus and lymphocytes.  Academic Article
• Brain-derived neurotrophic factor expression in granulosa lutein cells  Academic Article
• Calcium uptake by myometrial membranes: Effect of A 23187, a calcium ionophore  Academic Article
• Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro  Academic Article
• Changes in fluid secretion rate alter net transepithelial transport of MRP2 and P-glycoprotein substrates in Malpighian tubules ofDrosophila melanogaster  Academic Article
• Characterization of CHO-K1 cells stably expressing PDE-IV enzymes  Academic Article
• Characterization of Lithium Effects on Two Aspects of T-Cell Function  Academic Article
• Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition  Academic Article
• Cognitive Enhancement in Infants Associated with Increased Maternal Fruit Intake During Pregnancy: Results from a Birth Cohort Study with Validation in an Animal Model  Academic Article
• Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations  Academic Article
• Conformational and Biological Properties of Partial Sequences of Glucagon  Academic Article
• Conformational studies on analogs of recombinant parathyroid hormone and  Academic Article
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Academic Article
• Cyclic 3’,5’-Adenosine Monophosphate Mediates Dopamine D1-Stimulated Growth Hormone Release from Goldfish Pituitary Cells  Academic Article
• Cyclic AMP response to norepinephrine in the limbic forebrain of male and female rats: effect of desipramine  Academic Article
• Cyclic AMP-Independent Control of Twitching Motility in Pseudomonas aeruginosa  Academic Article
• Cyclic nucleotides and contractility of isolated soleus muscle.  Academic Article
• Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIα  Academic Article
• Desensitization by Antidepressants of Central Norepinephrine Receptor Systems Coupled to Adenylate Cyclase  Academic Article
• Desensitization of platelet α2-adrenoceptors after short term infusions of adrenoceptor agonist in man  Academic Article
• Detailed map of a cis-regulatory input function  Academic Article
• Divergent structural requirements exist for calcitonin receptor binding specificity and adenylate cyclase activation.  Academic Article
• Does naloxone induce relaxation of guinea-pig airway smooth muscle?  Academic Article
• Dynamic unfolding of a regulatory subunit of cAMP-dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability  Academic Article
• Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains  Academic Article
• Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model  Academic Article
• Effect of Oral Melatonin Administration on Melatonin, 5-Hydroxyindoleacetic Acid, Indoleacetic Acid, and Cyclic Nucleotides in Human Cerebrospinal Fluid  Academic Article
• Effect of opioid peptides onl-noradrenaline-stimulated cyclic AMP formation in homogenates of rat cerebral cortex and hypothalamus  Academic Article
• Effect of selective monoamine oxidase inhibition by clorgyline and deprenyl on the norepinephrine receptor-coupled adenylate cyclase system in rat cortex  Academic Article
• Effect of voltage and cyclic AMP on frequency of slow-wave-type action potentials in canine colon smooth muscle.  Academic Article
• Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles  Academic Article
• Effects of morphine on dopamine-stimulated adenylate cyclase and on cyclic GMP formation in primate brain amygdaloid nucleus  Academic Article
• Effects of phosphodiesterase inhibitors on normal and chemically-skinned isolated airway smooth muscle  Academic Article
• Effects on the buoyant density of rabbit platelets of ADP and agents that increase the concentration of cyclic AMP \textbar Request PDF  Article
• Enhancement of Amrinone-induced Positive Inotropy in Rabbit Papillary Muscles with Depressed Contractile Function: Effects on Cyclic Nucleotide Levels and Phosphodiesterase Isoenzymes  Academic Article
• Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP  Academic Article
• Expression of functional β-adrenoceptors and polyploidy development in cultured vascular smooth muscle cells from spontaneously hypertensive rats  Academic Article
• Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells  Academic Article
• Extracellular guanosine increases astrocyte cAMP  Academic Article
• Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit  Academic Article
• Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia  Academic Article
• Functional dynamics in cyclic nucleotide signaling and amyloid inhibition  Academic Article
• Growth homone-dependent potentiation of gonadotropin-stimulated steroid production by ovarian follicles of the goldfish  Academic Article
• Guanosine 5´-O-(3-Thiotriphosphate) and Cations Regulate Melatonin Receptors, and Melatonin Inhibits Cyclic AMP Production in the Spinal Cord  Academic Article
• Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway.  Academic Article
• Histamine: mercurial messenger in the gut  Academic Article
• Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin  Academic Article
• IL-6 is not essential for exercise-induced increases in glucose uptake  Academic Article
• Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors  Academic Article
• In vitro effects of ethanol on rabbit platelet aggregation, secretion of granule contents, and cyclic AMP levels in the presence of prostacyclin.  Academic Article
• Inhibition of VIP-stimulated intestinal secretion and cyclic AMP production by somatostatin in the rat  Academic Article
• Inhibition of fundic strips from guinea-pig stomach: The effect of theophylline on the membrane potential, muscle contraction and ion fluxes  Academic Article
• Inhibition of gonadotropin-stimulated ovarian steroid production by polyunsaturated fatty acids in teleost fish  Academic Article
• Inhibition of the calcium pump by human parathyroid hormone-(1-34) and human calcitonin in liver plasma membranes.  Academic Article
• Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure  Academic Article
• Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase  Academic Article
• Involvement of cAMP in the cytoplasmic control of meiotic cell division in Xenopus laevis oocytes.  Academic Article
• Is the attenuation of β-adrenergic agonist efficacy during labor caused by elevated prostaglandin E levels?  Conference Paper
• Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma  Academic Article
• Levels of cyclic GMP and cyclic AMP in regenerating forelimbs of adult newts following denervation  Academic Article
• Lithium: a Modulator of Cyclic AMP-Dependent Events in Lymphocytes?  Academic Article
• Long-term modulation of inward currents in O2 chemoreceptors by chronic hypoxia and cyclic AMP in vitro  Academic Article
• MOLECULAR AND PHARMACOLOGICAL CHARACTERISATION OF THE MSH-R ALLELES IN SWISS CATTLE BREEDS  Conference Paper
• Mapping allostery through the covariance analysis of NMR chemical shifts  Academic Article
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Academic Article
• Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR  Academic Article
• Measurement of both Cyclic [3H]AMP and Cyclic [3H]GMP in Cultured Vascular Smooth Muscle Cells Labeled with [3H]Hypoxanthine: Use in Studies of Cardiovascular Drugs  Academic Article
• Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist  Academic Article
• Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist  Academic Article
• Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)  Academic Article
• Melatonin receptors in the chicken kidney are up-regulated by pinealectomy and linked to adenylate cyclase  Academic Article
• Modification of platelet function  Article
• Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells  Academic Article
• Molecular and functional characterization of a partial cDNA encoding a novel chicken brain melatonin receptor  Academic Article
• Molecular control of rabbit follicular testosterone production: Role of cyclic AMP and cyclic GMP  Academic Article
• Multifactorial Regulation of Prostaglandin Synthesis in Preovulatory Goldfish Ovarian Follicles1  Academic Article
• Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors  Academic Article
• Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G  Academic Article
• NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit  Academic Article
• Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms  Academic Article
• Neurotransmitters modulate cytokine-stimulated interleukin 6 secretion in rat intestinal smooth muscle cells  Academic Article
• Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations  Academic Article
• Noradrenaline and cyclic AMP—independent growth stimulation in newt limb blastemata  Academic Article
• Nucleotide Second Messenger-Mediated Regulation of a Muralytic Enzyme inStreptomyces  Academic Article
• Nα-Trinitrophenyl glucagon An inhibitor of glucagon-stimulated cyclic AMP production and its effects on glycogenolysis  Academic Article
• Oxaprotiline: Induction of central noradrenergic subsensitivity by its (+)-enantiomer  Academic Article
• Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca ²⁺ Release and Cardiac Contractility, Independently of L-Type Ca ²⁺ Current  Academic Article
• Phosphorylation of casein by human erythrocyte membrane-bound protein kinase: competition of casein with endogenous substrates  Academic Article
• Plasticity in Cultured Arterial Chemoreceptors: Effects of Chronic Hypoxia and Cyclic AMP Analogs  Academic Article
• Plasticity in cultured carotid body chemoreceptors: Environmental modulation of GAP-43 and neurofilament  Academic Article
• Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP  Academic Article
• Prostaglandin E1: anomalous effects on glucose production in rat liver.  Academic Article
• Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis.  Academic Article
• Related RNA Polymerase-binding Regions in Human RAP30/74 And Escherichia coli σ70  Academic Article
• Relationship between cyclic AMP-stimulated and native gonadotropin-releasing hormone-stimulated gonadotropin release in the goldfish  Academic Article
• Role of AP-2α Transcription Factor in the Regulation of Synapsin II Gene Expression by Dopamine D1 and D2 Receptors  Academic Article
• Role of Dimers in the cAMP-Dependent Activation of Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels  Academic Article
• Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)  Academic Article
• Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels  Academic Article
• Roles for both cyclic GMP and cyclic AMP in the inhibition of collagen-induced platelet aggregation by nitroprusside*  Academic Article
• Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease  Academic Article
• Selective influence of ergot alkaloids on cortical and striatal dopaminergic and sergotonergic receptors.  Academic Article
• Signaling at Crossroads: The Dialogue between PDEs and PKA is Spoken in Multiple Languages  Academic Article
• Signaling through dynamic linkers as revealed by PKA  Academic Article
• Sleep in bipolar patients  Academic Article
• Somatostatin inhibits the secretion of bombesin-like peptides from small cell lung cancer cells  Academic Article
• Stimulation of Na⁺ , K⁺ -pump activity in skeletal muscle by methylxanthines: evidence and proposed mechanisms  Conference Paper
• Stimulation of Nerve Fiber Growth from Cultured Sympathetic Explants  Academic Article
• Stimulatory effects of selected PAHs on testosterone production in goldfish and rainbow trout and possible mechanisms of action  Academic Article
• Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I  Academic Article
• Studies on leukocyte β-adrenergic receptors in depression: A critical appraisal  Academic Article
• Supersensitivity in rat caudate nucleus: Effects of 6-hydroxydopamine on the time course of dopamine receptor and cyclic AMP changes  Academic Article
• Synergistic Effects of cAMP- and Calcium-Mediated Amylase Secretion in Isolated Pancreatic Acini from Cystic Fibrosis Mice  Academic Article
• Synergistic inhibitory effects of atriopeptin II and isoproterenol on contraction of rat aortic smooth muscle: roles of cGMP and cAMP  Academic Article
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻secretion blocked by a p38 MAPK inhibitor  Academic Article
• Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR  Academic Article
• The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR  Academic Article
• The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions  Academic Article
• The Inotropic Effect of 4−Aminopyridine and pH Changes in Rabbit Papillary Muscle  Academic Article
• The Mucosal Adjuvant Activities of ADP-Ribosylating Bacterial Enterotoxins  Academic Article
• The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants  Academic Article
• The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca 2+ activated Cl - conductance of Xenopus oocytes  Academic Article
• The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo  Academic Article
• The effect of aggregating agents on oxidative metabolism of rabbit platelets  Article
• The effect of prostaglandins E1, I2 and F2α on the shape and phosphatidylinositol-4,5-bisphosphate metabolism of washed rabbit platelets  Academic Article
• The essential role of the imidazole group of glucagon in its biological function  Academic Article
• The gastric caecum of larvalAedes aegypti: stimulation of epithelial ion transport by 5-hydroxytryptamine and cAMP  Academic Article
• The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction  Academic Article
• The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue  Academic Article
• The relationship between coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the anaesthetized rat.  Academic Article
• The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: Metoclopramide, thiethylperazine, and molindone as pharmacological tools  Academic Article
• The structure of the apocAMP‐binding domain ofHCN4 – a stepping stone toward understanding thecAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels  Academic Article
• Turnover and precursor-product relationships of nonlipid metabolites.  Academic Article
• Ultrasonic and Densimetric Characterization of the Association of Cyclic AMP with the cAMP-Binding Domain of the Exchange Protein EPAC1  Academic Article
• Understanding cAMP-Dependent Allostery by NMR Spectroscopy:  Comparative Analysis of the EPAC1 cAMP-Binding Domain in Its Apo and cAMP-Bound States  Academic Article
• Vascular β-adrenoceptor function in hypertension and in ageing  Academic Article
• cAMP activation of PKA defines an ancient signaling mechanism  Academic Article
• cAMP-dependent allostery and dynamics in Epac: an NMR view  Academic Article