Cyclic AMP Concept

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• 8-isoprostaglandin E2 activates Ca2+-dependent K+ current via cyclic AMP signaling pathway in murine renal artery  Journal Articles
• A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP  Journal Articles
• A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain  Journal Articles
• A Review of Candidate Pathways Underlying the Association Between Asthma and Major Depressive Disorder  Journal Articles
• A simple mathematical model of second-messenger mediated slow excitatory postsynaptic potentials.  Journal Articles
• Adrenergic regulation of HSL serine phosphorylation and activity in human skeletal muscle during the onset of exercise  Journal Articles
• Allosteric linkers in cAMP signalling  Journal Articles
• Analysis of epithelial K+ transport in Malpighian tubules ofDrosophila melanogaster: evidence for spatial and temporal heterogeneity  Journal Articles
• Arachidonic Acid and Prostaglandin E2 Stimulate Testosterone Production by Goldfish Testis in Vitro  Journal Articles
• Backbone resonance assignment of the cAMP-binding domains of the protein kinase A regulatory subunit Iα  Journal Articles
• Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.  Journal Articles
• Beta‐adrenoceptors in human lung, bronchus and lymphocytes.  Journal Articles
• Brain-derived neurotrophic factor expression in granulosa lutein cells  Journal Articles
• CAP2b, a cardioacceleratory peptide, is present in Drosophila and stimulates tubule fluid secretion via cGMP  Journal Articles
• Calcium uptake by myometrial membranes: Effect of A 23187, a calcium ionophore  Journal Articles
• Carotid Body Adaptation to Hypoxia: Cellular and Molecular Mechanisms in vitro  Journal Articles
• Changes in fluid secretion rate alter net transepithelial transport of MRP2 and P‐glycoprotein substrates in Malpighian tubules of Drosophila melanogaster  Journal Articles
• Characterization of CHO-K1 cells stably expressing PDE-IV enzymes  Journal Articles
• Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition  Journal Articles
• Cognitive Enhancement in Infants Associated with Increased Maternal Fruit Intake During Pregnancy: Results from a Birth Cohort Study with Validation in an Animal Model  Journal Articles
• Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations  Journal Articles
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Journal Articles
• Cyclic 3’,5’-Adenosine Monophosphate Mediates Dopamine D1-Stimulated Growth Hormone Release from Goldfish Pituitary Cells  Journal Articles
• Cyclic AMP response to norepinephrine in the limbic forebrain of male and female rats: effect of desipramine  Journal Articles
• Cyclic AMP-Independent Control of Twitching Motility in Pseudomonas aeruginosa  Journal Articles
• Cyclic nucleotides and contractility of isolated soleus muscle.  Journal Articles
• Definition of an electrostatic relay switch critical for the cAMP‐dependent activation of protein kinase A as revealed by the D170A mutant of RIα  Journal Articles
• Desensitization by Antidepressants of Central Norepinephrine Receptor Systems Coupled to Adenylate Cyclase^a  Journal Articles
• Desensitization of platelet α2-adrenoceptors after short term infusions of adrenoceptor agonist in man  Journal Articles
• Detailed map of a cis-regulatory input function  Journal Articles
• Diuretic factors and second messengers stimulate secretion of the organic cation TEA by the Malpighian tubules of Drosophila melanogaster  Journal Articles
• Does naloxone induce relaxation of guinea-pig airway smooth muscle?  Journal Articles
• Dynamic unfolding of a regulatory subunit of cAMP‐dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability  Journal Articles
• Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains  Journal Articles
• Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model  Journal Articles
• Effect of Oral Melatonin Administration on Melatonin, 5-Hydroxyindoleacetic Acid, Indoleacetic Acid, and Cyclic Nucleotides in Human Cerebrospinal Fluid  Journal Articles
• Effect of opioid peptides onl-noradrenaline-stimulated cyclic AMP formation in homogenates of rat cerebral cortex and hypothalamus  Journal Articles
• Effect of selective monoamine oxidase inhibition by clorgyline and deprenyl on the norepinephrine receptor-coupled adenylate cyclase system in rat cortex  Journal Articles
• Effect of voltage and cyclic AMP on frequency of slow‐wave‐type action potentials in canine colon smooth muscle.  Journal Articles
• Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles  Journal Articles
• Effects of morphine on dopamine-stimulated adenylate cyclase and on cyclic GMP formation in primate brain amygdaloid nucleus  Journal Articles
• Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle  Journal Articles
• Effects on the buoyant density of rabbit platelets of ADP and agents that increase the concentration of cyclic AMP \textbar Request PDF  Other
• Enhancement of Amrinone-induced Positive Inotropy in Rabbit Papillary Muscles with Depressed Contractile Function: Effects on Cyclic Nucleotide Levels and Phosphodiesterase Isoenzymes  Journal Articles
• Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP  Journal Articles
• Expression of functional β-adrenoceptors and polyploidy development in cultured vascular smooth muscle cells from spontaneously hypertensive rats  Journal Articles
• Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells  Journal Articles
• Extracellular guanosine increases astrocyte cAMP  Journal Articles
• Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit  Journal Articles
• Fractionation factors reveal hidden frustration in an ancient allosteric module  Journal Articles
• Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia  Journal Articles
• Functional dynamics in cyclic nucleotide signaling and amyloid inhibition  Journal Articles
• Growth homone-dependent potentiation of gonadotropin-stimulated steroid production by ovarian follicles of the goldfish  Journal Articles
• Guanosine 5´-O-(3-Thiotriphosphate) and Cations Regulate Melatonin Receptors, and Melatonin Inhibits Cyclic AMP Production in the Spinal Cord  Journal Articles
• Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway.  Journal Articles
• Histamine: mercurial messenger in the gut  Journal Articles
• Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin  Journal Articles
• IL-6 is not essential for exercise-induced increases in glucose uptake  Journal Articles
• Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors  Journal Articles
• In Vitro Effects of Ethanol on Rabbit Platelet Aggregation, Secretion of Granule Contents, and Cyclic AMP Levels in the Presence of Prostacyclin  Journal Articles
• In vitro effects of ethanol on rabbit platelet aggregation, secretion of granule contents, and cyclic AMP levels in the presence of prostacyclin.  Journal Articles
• Inhibition of VIP-stimulated intestinal secretion and cyclic AMP production by somatostatin in the rat  Journal Articles
• Inhibition of fundic strips from guinea-pig stomach: The effect of theophylline on the membrane potential, muscle contraction and ion fluxes  Journal Articles
• Inhibition of gonadotropin‐stimulated ovarian steroid production by polyunsaturated fatty acids in teleost fish  Journal Articles
• Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure  Journal Articles
• Involvement of cAMP in the cytoplasmic control of meiotic cell division in Xenopus laevis oocytes.  Journal Articles
• Leukotriene D₄ receptors are not negatively coupled to adenylyl cyclase in guinea‐pig lung parenchyma  Journal Articles
• Levels of cyclic GMP and cyclic AMP in regenerating forelimbs of adult newts following denervation  Journal Articles
• Long-term modulation of inward currents in O2 chemoreceptors by chronic hypoxia and cyclic AMP in vitro  Journal Articles
• MOLECULAR AND PHARMACOLOGICAL CHARACTERISATION OF THE MSH-R ALLELES IN SWISS CATTLE BREEDS  Conferences
• Mapping allostery through the covariance analysis of NMR chemical shifts  Journal Articles
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Journal Articles
• Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR  Journal Articles
• Measurement of both Cyclic [3H]AMP and Cyclic [3H]GMP in Cultured Vascular Smooth Muscle Cells Labeled with [3H]Hypoxanthine: Use in Studies of Cardiovascular Drugs  Journal Articles
• Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist  Journal Articles
• Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist  Journal Articles
• Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG)  Journal Articles
• Mechanisms of calcium sequestration by isolated Malpighian tubules of the house cricket Acheta domesticus  Journal Articles
• Melatonin receptors in the chicken kidney are up-regulated by pinealectomy and linked to adenylate cyclase  Journal Articles
• Modification of platelet function  Other
• Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells  Journal Articles
• Molecular and functional characterization of a partial cDNA encoding a novel chicken brain melatonin receptor  Journal Articles
• Molecular control of rabbit follicular testosterone production: Role of cyclic AMP and cyclic GMP  Journal Articles
• Multifactorial Regulation of Prostaglandin Synthesis in Preovulatory Goldfish Ovarian Follicles1  Journal Articles
• Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors  Journal Articles
• Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G  Journal Articles
• NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit  Journal Articles
• Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms  Journal Articles
• Neurotransmitters modulate cytokine-stimulated interleukin 6 secretion in rat intestinal smooth muscle cells  Journal Articles
• Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations  Journal Articles
• Noradrenaline and cyclic AMP—independent growth stimulation in newt limb blastemata  Journal Articles
• Novel Aspects Of The Transport Of Organic Anions By The Malpighian Tubules OfDrosophila Melanogaster  Journal Articles
• Nucleotide Second Messenger‐Mediated Regulation of a Muralytic Enzyme in Streptomyces  Journal Articles
• Oxaprotiline: Induction of central noradrenergic subsensitivity by its (+)-enantiomer  Journal Articles
• Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca ²⁺ Release and Cardiac Contractility, Independently of L-Type Ca ²⁺ Current  Journal Articles
• Phosphorylation of casein by human erythrocyte membrane-bound protein kinase: competition of casein with endogenous substrates  Journal Articles
• Plasticity in Cultured Arterial Chemoreceptors: Effects of Chronic Hypoxia and Cyclic AMP Analogs  Journal Articles
• Plasticity in cultured carotid body chemoreceptors: Environmental modulation of GAP‐43 and neurofilament  Journal Articles
• Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP  Journal Articles
• Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis.  Journal Articles
• Relationship between cyclic AMP-stimulated and native gonadotropin-releasing hormone-stimulated gonadotropin release in the goldfish  Journal Articles
• Role of AP-2α Transcription Factor in the Regulation of Synapsin II Gene Expression by Dopamine D1 and D2 Receptors  Journal Articles
• Role of Dimers in the cAMP-Dependent Activation of Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels  Journal Articles
• Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)  Journal Articles
• Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels  Journal Articles
• Roles for both cyclic GMP and cyclic AMP in the inhibition of collagen‐induced platelet aggregation by nitroprusside*  Journal Articles
• Salsalate, but not metformin or canagliflozin, slows kidney cyst growth in an adult-onset mouse model of polycystic kidney disease  Journal Articles
• Salt stress alters fluid and ion transport by Malpighian tubules ofDrosophila melanogaster: evidence for phenotypic plasticity  Journal Articles
• Secretion of Water and Ions by Malpighian Tubules of Larval Mosquitoes: Effects of Diuretic Factors, Second Messengers, and Salinity  Journal Articles
• Selective influence of ergot alkaloids on cortical and striatal dopaminergic and sergotonergic receptors.  Journal Articles
• Separate Control Of Anion And Cation Transport In Malpighian Tubules Of Drosophila Melanogaster  Journal Articles
• Signaling at Crossroads: The Dialogue between PDEs and PKA is Spoken in Multiple Languages  Journal Articles
• Signaling through dynamic linkers as revealed by PKA  Journal Articles
• Sleep in bipolar patients  Journal Articles
• Stimulation of Na⁺, K⁺‐pump activity in skeletal muscle by methylxanthines: evidence and proposed mechanisms  Conferences
• Stimulation of Nerve Fiber Growth from Cultured Sympathetic Explants  Journal Articles
• Stimulatory effects of selected PAHs on testosterone production in goldfish and rainbow trout and possible mechanisms of action  Journal Articles
• Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I  Journal Articles
• Studies on leukocyte β-adrenergic receptors in depression: A critical appraisal  Journal Articles
• Supersensitivity in rat caudate nucleus: Effects of 6-hydroxydopamine on the time course of dopamine receptor and cyclic AMP changes  Journal Articles
• Synergistic Effects of cAMP- and Calcium-Mediated Amylase Secretion in Isolated Pancreatic Acini from Cystic Fibrosis Mice  Journal Articles
• Synergistic inhibitory effects of atriopeptin II and isoproterenol on contraction of rat aortic smooth muscle: roles of cGMP and cAMP  Journal Articles
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor  Journal Articles
• Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR  Journal Articles
• The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR  Journal Articles
• The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions  Journal Articles
• The Inotropic Effect of 4−Aminopyridine and pH Changes in Rabbit Papillary Muscle  Journal Articles
• The Mucosal Adjuvant Activities of ADP-Ribosylating Bacterial Enterotoxins  Journal Articles
• The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants  Journal Articles
• The cystic fibrosis transmembrane conductance regulator attenuates the endogenous Ca 2+ activated Cl - conductance of Xenopus oocytes  Journal Articles
• The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo  Journal Articles
• The effect of aggregating agents on oxidative metabolism of rabbit platelets  Other
• The effect of prostaglandins E1, I2 and F2α on the shape and phosphatidylinositol-4,5-bisphosphate metabolism of washed rabbit platelets  Journal Articles
• The gastric caecum of larvalAedes aegypti: stimulation of epithelial ion transport by 5-hydroxytryptamine and cAMP  Journal Articles
• The inhibitory effects of exogenous arachidonic acid on rabbit platelet aggregation and the release reaction  Journal Articles
• The orphan pentameric ligand-gated ion channelpHCl-2is gated by pH and regulates fluid secretion inDrosophilaMalpighian tubules  Journal Articles
• The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue  Journal Articles
• The relationship between coronary artery occlusion-induced arrhythmias and myocardial cyclic nucleotide levels in the anaesthetized rat.  Journal Articles
• The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: Metoclopramide, thiethylperazine, and molindone as pharmacological tools  Journal Articles
• The structure of the apo cAMP‐binding domain of HCN4 – a stepping stone toward understanding the cAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels  Journal Articles
• Ultrasonic and Densimetric Characterization of the Association of Cyclic AMP with the cAMP-Binding Domain of the Exchange Protein EPAC1  Journal Articles
• Understanding cAMP-Dependent Allostery by NMR Spectroscopy:  Comparative Analysis of the EPAC1 cAMP-Binding Domain in Its Apo and cAMP-Bound States  Journal Articles
• Vascular β-adrenoceptor function in hypertension and in ageing  Journal Articles
• cAMP activation of PKA defines an ancient signaling mechanism  Journal Articles
• cAMP-dependent allostery and dynamics in Epac: an NMR view  Journal Articles