Journal article
Cyclic AMP-Independent Control of Twitching Motility in Pseudomonas aeruginosa
Abstract
FimV is a Pseudomonas aeruginosa inner membrane hub protein that modulates levels of the second messenger, cyclic AMP (cAMP), through the activation of adenylate cyclase CyaB. Although type IVa pilus (T4aP)-dependent twitching motility is modulated by cAMP levels, mutants lacking FimV are twitching impaired, even when exogenous cAMP is provided. Here we further define FimV's cAMP-dependent and -independent regulation of twitching. We confirmed …
Authors
Buensuceso RNC; Daniel-Ivad M; Kilmury SLN; Leighton TL; Harvey H; Howell PL; Burrows LL
Journal
Journal of Bacteriology, Vol. 199, No. 16, pp. 10.1128/jb.00188–10.1128/jb.00117
Publisher
American Society for Microbiology
Publication Date
August 15, 2017
DOI
10.1128/jb.00188-17
ISSN
0021-9193