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In vitro effects of ethanol on rabbit platelet...
Journal article

In vitro effects of ethanol on rabbit platelet aggregation, secretion of granule contents, and cyclic AMP levels in the presence of prostacyclin.

Abstract

Ethanol, at physiologically tolerable concentrations, inhibits platelet responses to low concentrations of collagen or thrombin, but does not inhibit responses of washed rabbit platelets stimulated with high concentrations of ADP, collagen, or thrombin. However, when platelet responses to high concentrations of collagen or thrombin had been partially inhibited by prostacyclin (PGI2), ethanol had additional inhibitory effects on aggregation and …

Authors

Rand ML; Gross PL; Jakowec DM; Packham MA; Mustard JF

Journal

Thromb Haemost, Vol. 61, No. 2, pp. 254–258

Publication Date

April 25, 1989

ISSN

0340-6245