Journal article
The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: Metoclopramide, thiethylperazine, and molindone as pharmacological tools
Abstract
The aim of the present studies was to further delineate the role of striatal and limbic dopaminergic versus limbic noradrenergic blockade in the pharmacologic and perhaps therapeutic action of antipsychotic drugs. Metoclopramide shares many properties of antipsychotic neuroleptic drugs, including the production of extrapyramidal side effects, but is not an efficacious antipsychotic agent. This drug was a potent blocker of dopamine (DA) …
Authors
Robinson SE; Berney S; Mishra R; Sulser F
Journal
Psychopharmacology, Vol. 64, No. 2, pp. 141–147
Publisher
Springer Nature
Publication Date
1 1979
DOI
10.1007/bf00496054
ISSN
0033-3158