Biochemical Journal
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Overview
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Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.
479:1317-1336.
2022
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Allosteric pluripotency: challenges and opportunities.
479:825-838.
2022
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AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.
478:3869-3889.
2021
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Mapping the interaction surface of scorpion β-toxins with an insect sodium channel.
478:2843-2869.
2021
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FoxA2 and RNA Pol II mediate human islet amyloid polypeptide turnover in ER-stressed pancreatic β-cells.
478:1261-1282.
2021
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Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.
477:4599-4601.
2020
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Current and emerging roles of adipose tissue in health and disease.
477:3645-3647.
2020
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Impact of pesticide exposure on adipose tissue development and function.
477:2639-2653.
2020
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The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice.
477:2347-2361.
2020
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Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.
477:1373-1389.
2020
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The NLRP3 inflammasome regulates adipose tissue metabolism.
477:1089-1107.
2020
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Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia.
476:3687-3704.
2019
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High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2.
475:1253-1265.
2018
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Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise.
474:557-569.
2017
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Small molecules reveal an alternative mechanism of Bax activation.
473:1073-1083.
2016
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PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle.
473:267-276.
2016
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Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis.
469:177-187.
2015
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Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity.
468:125-132.
2015
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Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax.
467:495-505.
2015
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Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.
461:177-188.
2014
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PIKfyve: a new fish in the growing pool of AMPK substrates.
455:e1-e3.
2013
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Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
454:191-200.
2013
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Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides.
419:377-385.
2009
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The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4.
419:57-63.
2009
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Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease.
418:185-190.
2009
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Regulation and function of triacylglycerol lipases in cellular metabolism.
414:313-325.
2008
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Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation.
391:191-202.
2005
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Characterization of the Bacillus subtilis GTPase YloQ and its role in ribosome function.
389:843-852.
2005
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Role of cis-acting elements in the control of SERCA2b Ca2+ pump mRNA decay by nuclear proteins.
388:291-297.
2005
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Probing the active site of YjeE: a vital Escherichia coli protein of unknown function.
384:577-584.
2004
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Role of transient receptor potential canonical 6 (TRPC6) in non-transferrin-bound iron uptake in neuronal phenotype PC12 cells.
378:975-982.
2004
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Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene.
378:519-528.
2004
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Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure.
364:157-163.
2002
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Dehydroascorbic acid uptake by coronary artery smooth muscle: effect of intracellular acidification.
362:507-512.
2002
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Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT.
360:699-699.
2001
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Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT.
360:699-706.
2001
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Treatment of PC12 cells with nerve growth factor increases iron uptake.
357:881-881.
2001
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Structure–function studies on Hsp47: pH-dependent inhibition of collagen fibril formation in vitro.
349:877-883.
2000
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Exon-skipping in BCR/ABL is induced by ABL exon 2.
348:63-69.
2000
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High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells.
342:497-497.
1999
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High-efficiency Semliki Forest virus-mediated transduction in bovine adrenal chromaffin cells.
342:497-501.
1999
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Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose transporter containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes.
341:861-863.
1999
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Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose transporter containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes (vol 331, pg 917, 1998).
341:861-861.
1999
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Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle.
338:167-167.
1999
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A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation.
336:283-285.
1998
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Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose-transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes.
333:847-848.
1998
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Correction: Actin filaments participate in the relocalization of phosphatidylinositol 3-kinase to glucose-transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes (Biochemical Journal (1998) 331 (917-928)).
333:848.
1998
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Characterization of the stress-inducing effects of homocysteine.
332:213-221.
1998
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Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes.
331:917-928.
1998
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Analysis of the interactions between an enzyme and multiple inhibitors using combination plots.
320:17-26.
1996
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Synergistic binding of inhibitors to the protease from HIV type 1.
315:113-117.
1996
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Peptidoglycan structure of Enterococcus faecium expressing vancomycin resistance of the VanB type.
313:711-715.
1996
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The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane.
313:487-494.
1996
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Combination plots as graphical tools in the study of enzyme inhibition.
311:981-985.
1995
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Phosphatidylinositol 3-kinase and the actin network are not required for the stimulation of glucose transport caused by mitochondrial uncoupling: comparison with insulin action.
309:1-5.
1995
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A direct role for serum albumin in the cellular uptake of long-chain fatty acids.
308:155-159.
1995
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Modulation of poly(ADP-ribose) polymerase during neutrophilic and monocytic differentiation of promyelocytic (NB4) and myelocytic (HL-60) leukaemia cells.
308:131-137.
1995
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Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C.
302:411-416.
1994
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Cytosolic calcium pre-elevation amplifies agonist-induced calcium release in human leukaemic HL-60 cells.
302:87-94.
1994
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Targeting of passenger protein domains to multiple intracellular membranes.
300:191-199.
1994
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Structural disruption of the trans-Golgi network does not interfere with the acute stimulation of glucose and amino acid uptake by insulin-like growth factor I in muscle cells.
297:289-295.
1994
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Subcellular-membrane characterization of [3H]ryanodine-binding sites in smooth muscle.
290:259-266.
1993
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Quantification of contributions of phospholipid precursors to diradylglycerols in stimulated mononuclear phagocytes.
284:367-375.
1992
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Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin.
283:893-897.
1992
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The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung.
283:487-491.
1992
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The N-terminal domain of antithrombin-III is essential for heparin binding and complex-formation with, but not cleavage by, α-thrombin.
282:345-351.
1992
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Heparin-binding serum protein(s) is required for the protection of sialyltransferase released during the incubation of rat jejunal slices.
280:687-693.
1991
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Expression of cyclic-nucleotide-sensitive and -insensitive isoforms of the plasma membrane Ca2+ pump in smooth muscle and other tissues.
277:345-349.
1991
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Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d-Phe-Pro-Arg-Ch2Cl.
272:399-406.
1990
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Alloxan inhibits ligand binding to adrenoceptors of vascular smooth muscle microsomes.
270:137-140.
1990
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Abundance of sarcoplasmic reticulum calcium pump isoforms in stomach and cardiac muscles.
268:415-419.
1990
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Metallothionein mRNA and protein induction by cadmium in peripheral-blood leucocytes.
262:873-879.
1989
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Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa.
257:143-150.
1989
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The plasma-membrane component is the primary site of action of alloxan on ATP-driven Ca2+ transport in vascular-muscle microsomal fractions.
254:293-296.
1988
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Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol.
251:279-284.
1988
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Increased sulphation improves the anticoagulant activities of heparan sulphate and dermatan sulphate.
248:889-896.
1987
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Phosphatidylinositol 4,5-bisphosphate is selectively retained by platelet-fibrin clots formed by thrombin.
245:649-653.
1987
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The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin.
243:579-588.
1987
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Involvement of phosphoinositide metabolism in potentiation by adrenaline of ADP-induced aggregation of rabbit platelets.
242:841-847.
1987
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The phosphoinositides exist in multiple metabolic pools in rabbit platelets.
238:411-417.
1986
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The decrease in phosphatidylinositol 4,5-bisphosphate in ADP-stimulated washed rabbit platelets is not primarily due to phospholipase C activation.
237:327-332.
1986
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Accumulation of the inositol phosphates in thrombin-stimulated, washed rabbit platelets in the presence of lithium.
224:399-405.
1984
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The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines.
224:505-514.
1984
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Changes in the platelet phosphoinositides during the first minute after stimulation of washed rabbit platelets with thrombin.
219:25-31.
1984
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Three types of human asialo-transferrin and their interactions with the rat liver.
184:399-407.
1979
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Bi- and tri-antennary human transferrin glycopeptides and their affinities for the hepatic lectin specific for asialo-glycoproteins.
181:633-638.
1979
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The assay and partial characterization of macromolecular heparin depolymerase activity in rat small intestine.
180:587-596.
1979
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Thiamin biosynthesis in Saccharomyces cerevisiae. Origin of carbon-2 of the thiazole moiety.
179:315-325.
1979
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3 TYPES OF HUMAN ASIALO-TRANSFERRIN AND THEIR INTERACTIONS WITH THE RAT-LIVER.
184:399-407.
1979
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BI-ANTENNARY AND TRI-ANTENNARY HUMAN TRANSFERRIN GLYCOPEPTIDES AND THEIR AFFINITIES FOR THE HEPATIC LECTIN SPECIFIC FOR ASIALO-GLYCOPROTEINS.
181:633-638.
1979
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Distinction between binding and endocytosis of human asialo-transferrin by the rat liver.
174:171-178.
1978
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Isolation and partial characterization of rabbit plasma α1-antitrypsin.
169:589-596.
1978
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Comparative studies of the cross-linked regions of elastin from bovine ligamentum nuchae and bovine, porcine and human aorta.
149:685-695.
1975
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Effect of nitrate on the synthesis and decay of nitrate reductase of Neurospora.
140:395-403.
1974
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Regulation of nitrate reductase of Neurospora at the level of transcription and translation.
134:673-685.
1973
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Purification and properties of dihydrofolate reductase from cultured mammalian cells.
133:349-356.
1973
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Studies on the coagulant enzyme from Agkistrodon rhodostoma venom. Isolation and some properties of the enzyme.
131:799-807.
1973
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The regulation of nitrate reductase in Neurospora crassa.
128:23P-23P.
1972
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Effect of nitrogenase compounds from mutant and wild-type strains of Azotobacter on the dilution effect of nitrogenase.
122:305-309.
1971
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The proteolytic action of Arvin on human fibrinogen.
118:603-609.
1970
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The proteolytic action of arvin on human fibrinogen.
115:17P-17P.
1969
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Effects of limiting different purine nucleotide precursors on nucleic acid synthesis and nucleotide pools of purine-requiring mutants of Escherichia coli.
114:42P-43P.
1969
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A note on the reduction potential of cysteine-cystine mixtures.
28:381-383.
1934
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