subject area of
- Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules ofDrosophila melanogaster Journal Articles
- Caenorhabditis elegansHistone Deacetylasehda-1Is Required for Morphogenesis of the Vulva and LIN-12/Notch-Mediated Specification of Uterine Cell Fates Journal Articles
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P eroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis Journal Articles - A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations Journal Articles
- Activin A Promotes Hematopoietic Fated Mesoderm Development Through Upregulation of Brachyury in Human Embryonic Stem Cells Journal Articles
- Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy Journal Articles
- An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity Journal Articles
- BRCA1 is a novel target to improve endothelial dysfunction and retard atherosclerosis Journal Articles
- Behavioral effects of non-viral mediated RNA interference of synapsin II in the medial prefrontal cortex of the rat Journal Articles
- Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation Journal Articles
- CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Journal Articles
- COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux Journal Articles
- Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β Journal Articles
- Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53 Journal Articles
- Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells Journal Articles
- Comparative analysis of function and interaction of transcription factors in nematodes: Extensive conservation of orthology coupled to rapid sequence evolution Journal Articles
- Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy Journal Articles
- Control of Centromere Localization of the MEI-S332 Cohesion Protection Protein Journal Articles
- Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3 Journal Articles
- Deciphering brain tumor heterogeneity, one cell at a time Journal Articles
- Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells Journal Articles
- Differential contribution of XPC, RAD23A, RAD23B and CENTRIN 2 to the UV-response in human cells Journal Articles
- Discovery and Use of Long dsRNA Mediated RNA Interference to Stimulate Antiviral Protection in Interferon Competent Mammalian Cells Journal Articles
- Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development Journal Articles
- EB1 Levels Are Elevated in Ascorbic Acid (AA)-stimulated Osteoblasts and Mediate Cell-Cell Adhesion-induced Osteoblast Differentiation Journal Articles
- EGFR-PLCγ1 signaling mediates high glucose-induced PKCβ1-Akt activation and collagen I upregulation in mesangial cells Journal Articles
- ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation Journal Articles
- Expression of xCT and activity of system xc− are regulated by NRF2 in human breast cancer cells in response to oxidative stress Journal Articles
- Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine Journal Articles
- Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease Journal Articles
- Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network Journal Articles
- Gal3ST-2 involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins Journal Articles
- Genetic Changes Accompanying the Evolution of Host Specialization in Drosophila sechellia Journal Articles
- Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response Journal Articles
- IQGAP2, A candidate tumour suppressor of prostate tumorigenesis Journal Articles
- Identification and functional analyses of sex determination genes in the sexually dimorphic stag beetle Cyclommatus metallifer Journal Articles
- Identification of likely orthologs of tobacco salicylic acid‐binding protein 2 and their role in systemic acquired resistance in Arabidopsis thaliana Journal Articles
- Induction of HIF-2α is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line Journal Articles
- Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin Journal Articles
- Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response Journal Articles
- Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained Journal Articles
- Lossless Compression of RNAi Fluorescence Images Using Regional Fluctuations of Pixels Journal Articles
- Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development Journal Articles
- Menin Is a Regulator of the Stress Response in Drosophila melanogaster Journal Articles
- Menin Links the Stress Response to Genome Stability in Drosophila melanogaster Journal Articles
- MiR-204 down-regulation elicited perturbation of a gene target signature common to human cholangiocarcinoma and gastric cancer Journal Articles
- Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop Journal Articles
- Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming Journal Articles
- Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways Journal Articles
- PHYOX2: a pivotal randomized study of nedosiran in primary hyperoxaluria type 1 or 2 Journal Articles
- PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer Journal Articles
- Proteins Required for Centrosome Clustering in Cancer Cells Journal Articles
- RNA Interference inCaenorhabditis elegans Journal Articles
- RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity Journal Articles
- RNAi screen identifies essential regulators of human brain metastasis-initiating cells Journal Articles
- Requirement and Redundancy of the Src Family Kinases Fyn and Lyn in Perforin-Dependent Killing of Cryptococcus neoformans by NK Cells Journal Articles
- Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression Journal Articles
- Role of PRY-1/Axin in heterochronic miRNA-mediated seam cell development Journal Articles
- Sam68 Allows Selective Targeting of Human Cancer Stem Cells Journal Articles
- Secondary-Structure Characterization of Two Proficient Kinase Deoxyribozymes Journal Articles
- Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits Journal Articles
- Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer Journal Articles
- Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics Journal Articles
- The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the β-catenin/TCF target gene matrilysin Journal Articles
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The small heat‐shock protein α
B ‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis Journal Articles - Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling Journal Articles
- Thrombospondin‐1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor‐related protein‐1 (LRP‐1) Journal Articles
- Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo Journal Articles
- VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection Journal Articles
- Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal muscle fibers Journal Articles
- p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor Journal Articles
- p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade Journal Articles
- α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells Journal Articles