Proteins Required for Centrosome Clustering in Cancer Cells Journal Articles

abstract

• Identified in an RNA interference screen, proteins that prevent spindle multipolarity in human cancer cells may prove to be promising drug targets.

authors

• Leber, Brian
• Maier, Bettina
• Fuchs, Florian
• Chi, Jing
• Riffel, Phillip
• Anderhub, Simon
• Wagner, Ludmila
• Ho, Anthony D
• Salisbury, Jeffrey L
• Boutros, Michael
• Krämer, Alwin

status

• published 

publication date

• May 26, 2010

has subject area

• 06 Biological Sciences (FoR)
• 11 Medical and Health Sciences (FoR)
• Animals (MeSH)
• Apoptosis (MeSH)
• Cell Line, Tumor (MeSH)
• Centrosome (MeSH)
• Chromatids (MeSH)
• Cytokinesis (MeSH)
• Genetic Testing (MeSH)
• Genome, Human (MeSH)
• Humans (MeSH)
• Kinetochores (MeSH)
• Microtubule Proteins (MeSH)
• Microtubules (MeSH)
• Multiprotein Complexes (MeSH)
• Neoplasms (MeSH)
• RNA Interference (MeSH)
• RNA, Small Interfering (MeSH)
• Spindle Apparatus (MeSH)

published in

• Science Translational Medicine  Journal

keywords

• Animals
• Apoptosis
• Cell Line, Tumor
• Centrosome
• Chromatids
• Cytokinesis
• Genetic Testing
• Genome, Human
• Humans
• Kinetochores
• Microtubule Proteins
• Microtubules
• Multiprotein Complexes
• Neoplasms
• RNA Interference
• RNA, Small Interfering
• Spindle Apparatus

Digital Object Identifier (DOI)

• 10.1126/scitranslmed.3000915

PubMed ID

• 20505215

start page

• 33ra38

volume

• 2

issue

• 33