Kidney Neoplasms Concept

subject area of

• 18F-DCFPyL PET/CT in Oncocytoma  Academic Article
• 2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-O-(3-thiotriphosphate).  Academic Article
• A "tumour trifecta:" myelolipomata arising within an adrenocortical adenoma ipsilateral to a synchronous clear cell renal cell carcinoma.  Academic Article
• A Multicentered, Propensity Matched Analysis Comparing Laparoscopic and Open Surgery for pT3a Renal Cell Carcinoma  Academic Article
• A Prospective Randomized Study of Pfannenstiel Versus Expanded Port Site Incision for Intact Specimen Extraction in Laparoscopic Radical Nephrectomy  Academic Article
• A Review of Pneumatosis Intestinalis in the Setting of Systemic Cancer Treatments, Including Tyrosine Kinase Inhibitors  Academic Article
• A Study of Mortality in Workers Engaged in the Mining, Smelting, and Refining of Nickel: Ii: Mortality from Cancer of the Respiratory Tract and Kidney  Academic Article
• A comprehensive multiattribute system for classifying the health status of survivors of childhood cancer.  Academic Article
• A novel endoscopic treatment for ureteric remnant hemorrhage post laparoscopic radical nephrectomy  Academic Article
• A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)  Academic Article
• A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium  Academic Article
• A quantitative model for spontaneous bone metastasis: evidence for a mitogenic effect of bone on Walker 256 cancer cells  Academic Article
• Active Surveillance, Radiofrequency Ablation, or Cryoablation for the Nonsurgical Management of a Small Renal Mass: A Cost-Utility Analysis  Academic Article
• Activity of cabozantinib after immune checkpoint blockade in metastatic clear-cell renal cell carcinoma  Academic Article
• Acute Perforative Appendicitis During Preoperative Chemotherapy for Wilms Tumor  Academic Article
• Acute histologic effects of temperature-based radiofrequency ablation on renal tumor pathologic interpretation  Academic Article
• Adjuvant Therapies in Nonmetastatic Renal-Cell Carcinoma: A Review of the Literature  Academic Article
• Adjuvant Weekly Girentuximab Following Nephrectomy for High-Risk Renal Cell Carcinoma  Academic Article
• Age-standardized cancer-incidence trends in Canada, 1971–2015  Academic Article
• An alternative approach to deal with the absence of clinical trials: a proportional meta-analysis of case series studies  Academic Article
• An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy  Academic Article
• Anastomosing Hemangioma of the Kidney: Radiologic and Pathologic Distinctions of a Kidney Cancer Mimic  Academic Article
• Application of Hereditary Renal Cell Carcinoma Risk Criteria to a Large Prospective Database  Academic Article
• Association between lymph node yield and survival among patients undergoing radical nephroureterectomy for urothelial carcinoma of the upper tract  Academic Article
• Attributable Risk in Practice  Academic Article
• C-Kit–positive metastatic malignant pigmented clear-cell epithelioid tumor arising from the kidney in a child without tuberous sclerosis  Academic Article
• Can 16-detector multislice CT exclude skeletal lesions during tumour staging? Implications for the cancer patient  Academic Article
• Can We Spare Removing the Adrenal Gland at Radical Nephrectomy in Children With Wilms Tumor?  Academic Article
• Cancer health effects of pesticides: systematic review.  Academic Article
• Cancer mortality associated with the high-temperature oxidation of nickel subsulfide.  Academic Article
• Change in neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma  Academic Article
• Checkpoint inhibitors in patients with metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium  Academic Article
• Child with Wilms' tumor and von Willebrand disease at diagnosis and apparent complete response to chemotherapy after multiple relapses  Academic Article
• Childhood cancers in Zambia before and after the HIV epidemic.  Academic Article
• Chromophobe renal cell carcinoma mimicking cortical invasion by synchronous invasive urothelial carcinoma of the intra-renal collecting system on CT urography  Academic Article
• Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin  Academic Article
• Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma  Academic Article
• Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma  Academic Article
• Comparison between laparoscopic and open radical nephrectomy for the treatment of primary renal tumors in children: Single-center experience over a 5-year period  Academic Article
• Comparison of Laparoscopic Radical Renal Surgery in Morbidly Obese and Non-obese Patients  Academic Article
• Comparison of Partial Versus Radical Nephrectomy Effect on Other-cause Mortality, Cancer-specific Mortality, and 30-day Mortality in Patients Older Than 75 Years  Academic Article
• Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma  Academic Article
• Congenital Orbital and Disseminated Extrarenal Malignant Rhabdoid Tumor  Academic Article
• Contrast-enhanced Ultrasonography for Surveillance of Radiofrequency-ablated Renal Tumors: A Prospective, Radiologist-blinded Pilot Study  Academic Article
• Cost-utility of Sunitinib Versus Pazopanib in Metastatic Renal Cell Carcinoma in Canada using Real-world Evidence  Academic Article
• Cryoablation vs radiofrequency ablation for the treatment of renal cell carcinoma: a meta-analysis of case series studies  Academic Article
• Current systemic management of metastatic renal cell carcinoma – first line and second line therapy  Academic Article
• Cytoreductive nephrectomy in metastatic renal cell carcinoma: the evolving role of surgery in the era of molecular targeted therapy  Academic Article
• DEFINING THE COMPLICATIONS OF CRYOABLATION AND RADIO FREQUENCY ABLATION OF SMALL RENAL TUMORS: A MULTI-INSTITUTIONAL REVIEW  Academic Article
• Diabetes and kidney cancer survival in patients undergoing nephrectomy: A Canadian multi-center, propensity score analysis  Academic Article
• Diagnosis of Sarcomatoid Renal Cell Carcinoma With CT: Evaluation by Qualitative Imaging Features and Texture Analysis  Academic Article
• Diagnostic Yield and Complication Rate in Percutaneous Needle Biopsy of Renal Hilar Masses With Comparison With Renal Cortical Mass Biopsies in a Cohort of 195 Patients  Academic Article
• Diagnostic accuracy of segmental enhancement inversion for the diagnosis of renal oncocytoma using biphasic computed tomography (CT) and multiphase contrast-enhanced magnetic resonance imaging (MRI)  Academic Article
• Differentiation of pancreatic neuroendocrine tumors from pancreas renal cell carcinoma metastases on CT using qualitative and quantitative features  Academic Article
• Disease progression and kidney function after partial vs. radical nephrectomy for T1 renal cancer  Academic Article
• Durable Clinical Benefit in Metastatic Renal Cell Carcinoma Patients Who Discontinue PD-1/PD-L1 Therapy for Immune-Related Adverse Events  Academic Article
• Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Vascular Changes Induced by Sunitinib in Papillary Renal Cell Carcinoma Xenograft Tumors  Academic Article
• EXPRESSION OF MULTIDRUG RESISTANCE-RELATED PROTEIN (MRP-1), LUNG RESISTANCE-RELATED PROTEIN (LRP) AND TOPOISOMERASE-II (TOPO-II) IN WILMS' TUMOR: IMMUNOHISTOCHEMICAL STUDY USING TMA METHODOLOGY  Academic Article
• Early onset of renal cancer in a family with Birt-Hogg-Dubé syndrome  Academic Article
• Early tumor shrinkage is independently associated with improved overall survival among patients with metastatic renal cell carcinoma: a validation study using the COMPARZ cohort  Academic Article
• Ectopic expression of alkaline phosphatase in proximal tubular brush border membrane of human renal cell carcinoma  Academic Article
• Editorial Comment  Academic Article
• Editorial Comment  Academic Article
• Effect of African-American race on cancer specific mortality differs according to clear cell vs. non-clear cell histologic subtype in metastatic renal cell carcinoma  Academic Article
• Effect of pathological high-risk features on cancer-specific mortality in non-metastatic clear cell renal cell carcinoma: a tool for optimizing patient selection for adjuvant therapy  Academic Article
• Endoplasmic Reticulum Protein ERp46 in Renal Cell Carcinoma  Academic Article
• Eosinophilic, Solid, and Cystic Renal Cell Carcinoma  Academic Article
• ErbB2 IS A TUMOR ASSOCIATED ANTIGEN AND A SUITABLE THERAPEUTIC TARGET IN WILMS TUMOR  Academic Article
• Estrogen and progesterone binding sites in renal cell carcinoma  Academic Article
• Evaluating Hemorrhage in Renal Cell Carcinoma Using Susceptibility Weighted Imaging  Academic Article
• Evaluating Treatments for Childhood Cancer: A Process for Critical Appraisal of the Literature and a Summary of the Results  Academic Article
• Evaluation of T1-Weighted MRI to Detect Intratumoral Hemorrhage Within Papillary Renal Cell Carcinoma as a Feature Differentiating From Angiomyolipoma Without Visible Fat  Academic Article
• Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma  Academic Article
• Evolving Role of Urologists in the Management of Advanced Renal Cell Carcinoma  Academic Article
• Expression of Cyclooxygenase-2 in Wilms Tumor: Immunohistochemical Study Using Tissue Microarray Methodology  Conference Paper
• External validation of a predictive model of survival after cytoreductive nephrectomy for metastatic renal cell carcinoma  Academic Article
• Formal clinical evaluation of the CADD-Micro system for circadian delivery of FUDR in patients with metastatic renal cell cancer.  Academic Article
• Fumarate Hydratase–deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome  Academic Article
• Genitourinary Cancer Predisposition Syndromes  Academic Article
• Growth characteristics of renal cortical tumors in patients managed by watchful waiting.  Academic Article
• High‐grade oncocytic tumour (HOT) of kidney in a patient with tuberous sclerosis complex  Academic Article
• INHIBITION OF WILMS TUMOR XENOGRAFT PROGRESSION BY HALOFUGINONE IS ACCOMPANIED BY ACTIVATION OF WT-1 GENE EXPRESSION  Conference Paper
• Imaging in Renal Cell Carcinoma  Academic Article
• Immunotherapy in the Elderly  Academic Article
• Impact of Tumor Size on Cancer-Specific Mortality Rate After Local Tumor Ablation in T1a Renal-Cell Carcinoma  Academic Article
• Incidence of Radionecrosis in Single-Fraction Radiosurgery Compared with Fractionated Radiotherapy in the Treatment of Brain Metastasis  Academic Article
• Influence of Contrast Administration on Computed Tomography-Based Analysis of Visceral Adipose and Skeletal Muscle Tissue in Clear Cell Renal Cell Carcinoma  Academic Article
• Intact Specimen Extraction in Laparoscopic Nephrectomy Procedures: Pfannenstiel Versus Expanded Port Site Incisions  Academic Article
• Inter-observer agreement of a comprehensive health status classification system for pre-school children among patients with Wilms? tumor or advanced  Academic Article
• Interobserver and intraobserver variability using the Fuhrman grading system for renal cell carcinoma.  Academic Article
• Intracellular lipid in clear cell renal cell carcinoma tumor thrombus and metastases detected by chemical shift (in and opposed phase) MRI: radiologic-pathologic correlation  Academic Article
• Intracellular lipid in papillary renal cell carcinoma (pRCC): T2 weighted (T2W) MRI and pathologic correlation  Academic Article
• Is There a Role for Adjuvant Therapy After Surgery in “High Risk for Recurrence” Kidney Cancer? an Update on Current Concepts  Academic Article
• Langerhans Cell Histiocytosis Associated With Renal Cell Carcinoma Is a Neoplastic Process  Conference Paper
• Laparoscopic Management of Advanced Renal Cell Carcinoma With Renal Vein and Inferior Vena Cava Thrombus  Academic Article
• Laparoscopic management of advanced renal cell carcinoma with level I renal vein thrombus  Academic Article
• Laparoscopic versus open partial nephrectomy  Academic Article
• Laparoscopic wedge resection of a renal mass in a solitary kidney.  Academic Article
• Liver scanning in malignant genitourinary tumours.  Academic Article
• Lower Plasma Adiponectin Levels Are Associated with Larger Tumor Size and Metastasis in Clear-Cell Carcinoma of the Kidney  Academic Article
• MG98, a Second-Generation DNMT1 Inhibitor, in the Treatment of Advanced Renal Cell Carcinoma  Academic Article
• Management of Small Renal Masses: American Society of Clinical Oncology Clinical Practice Guideline  Academic Article
• Manifestations of Von Hippel Lindau syndrome: a retrospective national review  Academic Article
• Marital status and gender affect stage, tumor grade, treatment type and cancer specific mortality in T1–2 N0 M0 renal cell carcinoma  Academic Article
• Meta-analysis of cryoablation versus microwave ablation for small renal masses: is there a difference in outcome?  Academic Article
• Metabolomic adaptations and correlates of survival to immune checkpoint blockade  Academic Article
• Metastatic Merkel cell tumor to the prostate and bladder  Academic Article
• Metastatic Renal Carcinoma: Evaluation of Antiangiogenic Therapy with Dynamic Contrast-enhanced CT  Academic Article
• Metastatic renal cell cancer treatments: An indirect comparison meta-analysis  Academic Article
• Morphologic subtyping as a prognostic predictor for survival in papillary renal cell carcinoma: Type 1 vs. type 2  Academic Article
• Mortality in Incident Maintenance Dialysis Patients Versus Incident Solid Organ Cancer Patients: A Population-Based Cohort  Academic Article
• Mortality in Vermont granite workers and its association with silica exposure  Academic Article
• Multifocality rather than tumor location is a prognostic factor in upper tract urothelial carcinoma  Academic Article
• Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney  Academic Article
• Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study  Academic Article
• Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations  Academic Article
• Objective Responses in Patients with Malignant Melanoma or Renal Cell Cancer in Early Clinical Studies Do Not Predict Regulatory Approval  Academic Article
• Osseous metastases secondary to renal cell carcinoma  Academic Article
• Osteopenia in survivors of Wilms tumor  Academic Article
• PET/CT and Renal Pathology: A Blind Spot for Radiologists? Part 1, Primary Pathology  Academic Article
• PET/CT and Renal Pathology: A Blind Spot for Radiologists? Part 2—Lymphoma, Leukemia, and Metastatic Disease  Academic Article
• Paravaginal Female Adnexal Tumor of Probable Wolffian Origin  Academic Article
• Partial nephrectomy seems to confer a survival benefit relative to radical nephrectomy in metastatic renal cell carcinoma  Academic Article
• Pathological Upstaging of Clinical T1 to Pathological T3a Renal Cell Carcinoma: A Multi-institutional Analysis of Short-term Outcomes  Academic Article
• Permanent flank bulge is a consequence of flank incision for radical nephrectomy in one half of patients  Academic Article
• Persistent dry cough: an unusual presentation of renal cell carcinoma  Academic Article
• Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)  Academic Article
• Plasma exchange for myeloma kidney: cast(s) away?  Academic Article
• Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities  Academic Article
• Poland's syndrome and Wilms tumor: An unusual association  Academic Article
• Pooled analysis of stereotactic ablative radiotherapy for primary renal cell carcinoma: A report from the International Radiosurgery Oncology Consortium for Kidney (IROCK)  Academic Article
• Predictive factors of chronic kidney disease stage V after partial nephrectomy in a solitary kidney: a multi-institutional study  Academic Article
• Prognostic Impact of Muscular Venous Branch Invasion in Localized Renal Cell Carcinoma Cases  Academic Article
• Prognostic Implications of the Immunohistochemical Expression of Human Kallikreins 5, 6, 10 and 11 in Renal Cell Carcinoma  Academic Article
• Prognostic factors in patients with small renal masses: a comparison between <2 vs. 2.1–4 cm renal cell carcinomas  Academic Article
• Prostate-Specific antigen expression by various tumors  Academic Article
• Proton Pump Inhibitors and Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma  Academic Article
• Radiofrequency Ablation of Renal Tumors: Intermediate-Term Results  Conference Paper
• Renal Cell Carcinoma With Xp 11.2 Translocation as a Second Tumor in a Long-Term Survivor of Advanced Neuroblastoma  Academic Article
• Renal Cell Carcinoma in the Canadian Indigenous Population  Academic Article
• Renal Cell Carcinoma: Comparison between Variant Histology and Clear Cell Carcinoma across All Stages and Treatment Modalities  Academic Article
• Renal cell carcinoma in a pelvic kidney  Academic Article
• Renal cell carcinoma with mixed features of papillary and clear cell cytomorphology: a fluorescent in situ hybridization study  Academic Article
• Renal epithelioid angiomyolipoma: a study of six cases and a meta-analytic study. Development of criteria for screening the entity with prognostic significance  Academic Article
• Renal extramedullary haematopoiesis mimicking renal lymphoma on computed tomography  Academic Article
• Renal hypothermia during partial nephrectomy for patients with renal tumours: a randomised controlled clinical trial protocol  Academic Article
• Renal radiofrequency ablation: Technique and results  Conference Paper
• Response of Primary Renal Cell Carcinoma to Systemic Therapy  Academic Article
• Response to single agent PD-1 inhibitor after progression on previous PD-1/PD-L1 inhibitors: a case series  Academic Article
• Results of the ADAPT Phase 3 Study of Rocapuldencel-T in Combination with Sunitinib as First-Line Therapy in Patients with Metastatic Renal Cell Carcinoma  Academic Article
• Reversible Cabozantinib-Induced Cardiomyopathy  Academic Article
• Risk of Nephrectomy in Previous Living Kidney Donors  Academic Article
• SDH-deficient renal cell carcinoma – clinical, pathologic and genetic correlates: a case report  Academic Article
• Safety and Efficacy of Sorafenib in Elderly Patients Treated in the North American Advanced Renal Cell Carcinoma Sorafenib Expanded Access Program  Academic Article
• Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America  Academic Article
• Safety, reliability and accuracy of small renal tumour biopsies: results from a multi-institution registry  Academic Article
• Selective thrombocytopenia in children with Wilms tumor: An immune-mediated effect of dactinomycin?  Academic Article
• Short-term efficacy of temperature-based radiofrequency ablation of small renal tumors  Academic Article
• Solitary renal cell carcinoma metastasis to the hand: The need for wide excision or amputation  Academic Article
• Specific Reduction of Fas-Associated Protein with Death Domain (FADD) in Clear Cell Renal Cell Carcinoma  Academic Article
• Survival after Cytoreductive Nephrectomy in Metastatic Non-clear Cell Renal Cell Carcinoma Patients: A Population-based Study  Academic Article
• Survival of metastatic renal cell carcinoma patients continues to improve over time, even in targeted therapy era  Academic Article
• Systemic Treatment of Metastatic Clear Cell Renal Cell Carcinoma in 2018: Current Paradigms, Use of Immunotherapy, and Future Directions  Academic Article
• THE RADIOGRAPHIC EVOLUTION OF RADIO FREQUENCY ABLATED RENAL TUMORS  Conference Paper
• TUMOR CAPACITANCE: ELECTRICAL MEASUREMENTS OF RENAL NEOPLASIA  Academic Article
• Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma  Academic Article
• Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma  Academic Article
• Telomere crisis in kidney epithelial cells promotes the acquisition of a microRNA signature retrieved in aggressive renal cell carcinomas  Academic Article
• Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma  Academic Article
• The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non–Clear Cell Renal Cell Carcinoma  Academic Article
• The Contemporary Role of Lymph Node Dissection During Nephroureterectomy in the Management of Upper Urinary Tract Urothelial Carcinoma: The Canadian Experience  Academic Article
• The Effect of Institution Teaching Status on Perioperative Outcomes After Robotic Partial or Radical Nephrectomy  Academic Article
• The current status of embolization in renal cell carcinoma — A survey of local and national practice  Academic Article
• The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial  Academic Article
• The evaluation of biologically important trace metals in liver, kidney and breast tissue  Academic Article
• The future of perioperative therapy in advanced renal cell carcinoma: how can we PROSPER?  Academic Article
• The impact of lymph node dissection and positive lymph nodes on cancer-specific mortality in contemporary pT2-3 non-metastatic renal cell carcinoma treated with radical nephrectomy  Academic Article
• The method of bladder cuff excision during laparoscopic radical nephroureterectomy does not affect oncologic outcomes in upper tract urothelial carcinoma  Academic Article
• The natural history of renal function after surgical management of renal cell carcinoma: Results from the Canadian Kidney Cancer Information System  Academic Article
• The prognostic significance of nodal disease burden in patients with lymph node metastases from renal cell carcinoma  Academic Article
• Thermal Versus Impedance-Based Ablation of Renal Cell Carcinoma: A Meta-analysis  Academic Article
• Treatment of Osseous Metastases in Patients With Renal Cell Carcinoma  Academic Article
• Tumor Ablation Treatment Planning Coupled to Robotic Implementation: A Feasibility Study  Academic Article
• Two unusual tumours of the gastrointestinal tract in a patient with tuberous sclerosis  Academic Article
• Unbalanced translocation of chromosome 3p in Wilms' tumor  Academic Article
• Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression  Academic Article
• Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo  Academic Article
• Unenhanced CT for the Diagnosis of Minimal-Fat Renal Angiomyolipoma  Academic Article
• Update of the ICUD-SIU consultation on upper tract urothelial carcinoma 2016: treatment of low-risk upper tract urothelial carcinoma  Academic Article
• Update on Cryoablation for Treatment of Small Renal Mass: Oncologic Control, Renal Function Preservation, and Rate of Complications  Academic Article
• Use of Targeted Therapy in Patients with Metastatic Renal Cell Carcinoma: Clinical and Economic Impact in a Canadian Real-Life Setting  Academic Article
• Using the Delphi Technique to Improve Clinical Outcomes Through the Development of Quality Indicators in Renal Cell Carcinoma  Academic Article
• Validation of Region of Interest Measurements for the Objective Assessment of Post-Contrast Enhancement of Renal Lesions on MRI  Academic Article
• Validation of a Postoperative Nomogram Predicting Recurrence in Patients with Conventional Clear Cell Renal Cell Carcinoma  Academic Article
• Volumetric assessment of unaffected parenchyma and Wilms’ tumours: analysis of response to chemotherapy and surgery using a semi-automated segmentation algorithm in children with renal neoplasms  Academic Article
• [Radiological signs of primary sarcoma of the kidney in adults : a report on 5 cases (author's transl)].  Academic Article
• “High-grade oncocytic renal tumor”: morphologic, immunohistochemical, and molecular genetic study of 14 cases  Academic Article