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Endoplasmic Reticulum Protein ERp46 in Renal Cell...
Journal article

Endoplasmic Reticulum Protein ERp46 in Renal Cell Carcinoma

Abstract

An established inverse clinical correlation between serum adiponectin levels and renal cell carcinoma (RCC) aggressiveness exists. We have recently demonstrated that adiponectin suppresses clear cell RCC (ccRCC) progression through interaction with its receptor, adiponectin receptor 1 (AdipoR1). ERp46 has been shown to inhibit adiponectin signaling via interaction with AdipoR1 in HeLa cells. However, the expression of ERp46 in RCC has not been …

Authors

Duivenvoorden WCM; Paschos A; Hopmans SN; Austin RC; Pinthus JH

Journal

PLOS ONE, Vol. 9, No. 3,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0090389

ISSN

1932-6203