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Does a Positive Surgical Margin After Nephron...
Journal article

Does a Positive Surgical Margin After Nephron Sparing Surgery Affect Oncological Outcome in Renal Cell Carcinoma? A Systematic Review and Meta-analysis

Abstract

We systematically evaluated the impact of positive surgical margins (PSM) on oncological outcomes after partial nephrectomy for renal cell carcinoma. Forty-two studies comprising 101,153 subjects were included and five distinct meta-analyses were performed. PSM was associated with increased risk of local recurrence (hazard ratio (HR) 6.11-high certainty), metastasis (HR 3.29-moderate certainty), overall relapse (HR 2.25-high certainty), overall …

Authors

Hakam N; Abou Heidar N; Khabsa J; Hneiny L; Akl EA; Khauli R

Journal

Urology, Vol. 156, , pp. e30–e39

Publisher

Elsevier

Publication Date

October 2021

DOI

10.1016/j.urology.2021.04.058

ISSN

0090-4295