Journal article
Associations between Pretreatment Body Composition Features and Clinical Outcomes among Patients with Metastatic Clear Cell Renal Cell Carcinoma Treated with Immune Checkpoint Blockade.
Abstract
PURPOSE: High body mass index (BMI) may lead to improved immune-checkpoint blockade (ICB) outcomes in metastatic clear cell renal cell carcinoma (mccRCC). However, BMI is a crude body size measure. We investigated BMI and radiographically assessed body composition (BC) parameters association with mccRCC ICB outcomes.
EXPERIMENTAL DESIGN: Retrospective study of ICB-treated patients with mccRCC. BMI and BC variables [skeletal muscle index (SMI) …
Authors
Ged Y; Sanchez A; Patil S; Knezevic A; Stein E; Petruzella S; Weiss K; Duzgol C; Chaim J; Akin O
Journal
Clinical Cancer Research, Vol. 28, No. 23, pp. 5180–5189
Publisher
American Association for Cancer Research (AACR)
Publication Date
December 1, 2022
DOI
10.1158/1078-0432.ccr-22-1389
ISSN
1078-0432