Journal article
Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma
Abstract
BackgroundThe genomic landscape of primary clear cell renal cell carcinoma (ccRCC) has been well described. However, little is known about cohort genomic alterations (GA) landscape in ccRCC metastases, or how it compares to primary tumours in aggregate. The genomic landscape of metastases may have biological, clinical, and therapeutic implications.MethodsWe collected targeted next-generation sequencing mutation calls from two independent …
Authors
de Velasco G; Wankowicz SA; Madison R; Ali SM; Norton C; Duquette A; Ross JS; Bossé D; Lalani A-KA; Miller VA
Journal
British Journal of Cancer, Vol. 118, No. 9, pp. 1238–1242
Publisher
Springer Nature
Publication Date
May 2018
DOI
10.1038/s41416-018-0064-3
ISSN
0007-0920