Cell Transformation, Neoplastic Concept

subject area of

• 65‐year‐old female with cerebellopontine angle lesion  Journal Articles
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Journal Articles
• A UV-specific endonucleolytic activity present in human cell extracts  Journal Articles
• A case of refractory Sézary syndrome with large-cell transformation responsive to brentuximab vedotin.  Journal Articles
• A plasmid vehicle suitable for the molecular cloning and characterization of mammalian promoters  Journal Articles
• A transgenic mouse line harboring a smooth muscle alpha-actin promoter polyomavirus middle T antigen transgene develops an epithelial hyperplasia in the rectum and distal stomach.  Journal Articles
• A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis  Journal Articles
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Journal Articles
• Actions of radiation on living cells in the “post-bystander” era  Journal Articles
• Adherence to Guidelines for Surveillance Colonoscopy in Patients with Ulcerative Colitis at a Canadian Quaternary Care Hospital  Journal Articles
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Journal Articles
• An Immunohistological Comparison of Primary Lung Carcinosarcoma and Sarcoma  Journal Articles
• An Interactive Web-Based Educational Tool Improves Detection and Delineation of Barrett’s Esophagus–Related Neoplasia  Journal Articles
• Apoptosis and other effects of radiation in normal human urothelial cells  Journal Articles
• Autologous and Allogeneic Stem-Cell Transplantation for Transformed Follicular Lymphoma: A Report of the Canadian Blood and Marrow Transplant Group  Journal Articles
• Basophil production in myeloproliferative disorders: increases during acute blastic transformation of chronic myeloid leukemia  Journal Articles
• Biological Activity of Tumor Virus Dna  Journal Articles
• Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation  Journal Articles
• Borderline mucinous cystic tumor in jejunal pancreatic heterotopia  Journal Articles
• Brain Tumor Stem Cells: Identification and Concepts  Journal Articles
• Butein impairs the protumorigenic activity of malignant pleural mesothelioma cells  Journal Articles
• Cancer stem cells in nervous system tumors  Journal Articles
• Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex  Journal Articles
• Cellular processes of v-Src transformation revealed by gene profiling of primary cells - Implications for human cancer  Journal Articles
• Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5  Journal Articles
• Combined analysis of cervical smears. Cytopathology, image cytometry and in situ hybridization.  Journal Articles
• Complete genomic landscape of a recurring sporadic parathyroid carcinoma  Journal Articles
• Concepts of human leukemic development  Journal Articles
• Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.  Journal Articles
• Contribution of Electron Microscopy to Understanding Cellular Differentiation in Mesenchymal Tumors of the Gastrointestinal Tract: A Study of 82 Tumors  Journal Articles
• Covalently closed circles of human adenovirus DNA are infectious.  Journal Articles
• Defective repair of UV-damaged DNA in human tumor and SV40-transformed human cells but not in adenovirus-transformed human cells  Journal Articles
• Defective transforming capacity of adenovirus type 5 host-range mutants  Journal Articles
• Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions  Journal Articles
• Detection of SYT–SSX1/2 fusion transcripts by reverse transcriptase–polymerase chain reaction (RT–PCR) is a valuable diagnostic tool in synovial sarcoma  Journal Articles
• Deterministic evolution and stringent selection during preneoplasia  Journal Articles
• Development of transformed characteristics by sheep thyroid cells irradiated as differentiated primary cultures  Journal Articles
• Dysplasia to carcinoma transformation in ulcerative colitis  Journal Articles
• Evidence for the transmission of neoplastic properties from transformed to normal human stem cells  Journal Articles
• Expression of Lethal Mutations Is Suppressed in Neoplastically Transformed Cells and after Treatment of Normal Cells with Carcinogens  Journal Articles
• Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells.  Journal Articles
• Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy  Journal Articles
• From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration  Journal Articles
• Functional role of BAALC in leukemogenesis  Journal Articles
• GBM secretome induces transient transformation of human neural precursor cells  Journal Articles
• GFI1 is required for RUNX1/ETO positive acute myeloid leukemia  Journal Articles
• Generation of Murine Xenograft Models of Brain Tumors from Primary Human Tissue for In Vivo Analysis of the Brain Tumor-Initiating Cell  Journal Articles
• Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo  Journal Articles
• Growth of 293 Cells in Suspension Culture  Journal Articles
• Hippo pathway dysregulation in gastric cancer: from Helicobacter pylori infection to tumor promotion and progression  Journal Articles
• Host-range mutants of adenovirus type 5 defective for growth in HeLa cells  Journal Articles
• Human acute myeloid leukemia stem cells  Journal Articles
• IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors.  Journal Articles
• IQGAP2, A candidate tumour suppressor of prostate tumorigenesis  Journal Articles
• Identification of Adenovirus E1A Regions Which Affect MHC Class I Expression and Susceptibility to Cytotoxic T Lymphocytes  Journal Articles
• Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.  Journal Articles
• In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation  Journal Articles
• Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1  Journal Articles
• Iron incorporation into ferritin and hemoglobin during differentiation of murine erythroleukemia cells  Journal Articles
• Isolation and Characterization of Mesenchymal Stem Cells From the Sub-Amniotic Human Umbilical Cord Lining Membrane  Journal Articles
• Lactate-mediated changes in growth morphology and transformation frequency of irradiated C3h cells  Journal Articles
• Lethal mutations and genomic instability  Journal Articles
• Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer  Journal Articles
• Malignant Transformation Within Ovarian Dermoid Cysts  Journal Articles
• Malignant transformation of a solitary tracheal papilloma in the absence of human papillomavirus infection in a patient with 48, XYYY syndrome: case report  Journal Articles
• Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice*  Journal Articles
• Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo  Journal Articles
• Mathematical model for the cancer stem cell hypothesis  Journal Articles
• Medulloblastoma stem cells: where development and cancer cross pathways  Journal Articles
• MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway  Journal Articles
• Mitochondria and Cancer: Past, Present, and Future  Journal Articles
• Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13  Journal Articles
• Modeling the Initiation and Progression of Human Acute Leukemia in Mice  Journal Articles
• Modelling the MYC-driven normal-to-tumour switch in breast cancer.  Journal Articles
• Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity  Journal Articles
• NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells  Journal Articles
• Nonrandom chromosomal abnormalities in bovine lymphoma  Journal Articles
• Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis  Journal Articles
• Omics Underpins Novel Clues on VDR Chemoprevention Target in Breast Cancer  Journal Articles
• Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis  Journal Articles
• Orthotopic, syngeneic mouse model to study the effects of epithelial-stromal interaction  Journal Articles
• PKM2 contributes to cancer metabolism  Journal Articles
• Pathway Pathology  Journal Articles
• Pleuropulmonary blastoma  Journal Articles
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Journal Articles
• Polyomavirus-plasmid recombinants capable of replicating have an enhanced transforming potential.  Journal Articles
• Prognostic implications of basophil differentiation in chronic myeloid leukemia  Journal Articles
• Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma  Journal Articles
• Progression toward malignancy of hamartomas in a patient with Peutz-Jeghers syndrome: case report and literature review.  Journal Articles
• Proliferative verrucous leukoplakia and erythroplakia are probably the disorders with the highest rate of malignant transformation  Journal Articles
• Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53  Journal Articles
• Radiation-induced bystander effects — implications for cancer  Journal Articles
• Regulation of gene expression in oncogenically transformed cells  Journal Articles
• Relation of Herpes Simplex Viruses to Human Malignancies  Journal Articles
• Repression of quiescence-specific polypeptides in chicken heart mesenchymal cells transformed by Rous sarcoma virus.  Journal Articles
• Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry.  Journal Articles
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Journal Articles
• Reversibility and recurrence of IGF-IR-induced mammary tumors  Journal Articles
• S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia  Journal Articles
• SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells  Journal Articles
• Simultaneous or sequential expression of lymphoid and myeloid phenotypes in acute leukemia  Journal Articles
• Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation  Journal Articles
• Size and location of the transforming region in human adenovirus type 5 DNA  Journal Articles
• Studies on In Vitro Transformation by DNA and DNA Fragments of Human Adenoviruses and Simian Virus 40  Journal Articles
• Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin  Journal Articles
• Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells  Journal Articles
• Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction  Journal Articles
• Telomerase activity associated with acquisition of malignancy in human colorectal cancer.  Journal Articles
• Telomerase, Cell Immortality, and Cancer  Journal Articles
• Telomere maintenance in tumour cells.  Journal Articles
• Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.  Journal Articles
• The Adverse Consequences of Initial Watchful Waiting for Patients With Follicular Lymphoma  Journal Articles
• The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB  Journal Articles
• The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation  Journal Articles
• The Influence of Lethal Mutations on the Quantification of Radiation Transformation Frequencies  Journal Articles
• The amino terminus of polyomavirus middle T antigen is required for transformation  Journal Articles
• The effect of radiation in combination with carcinogens on the growth of normal urothelium in explant culture  Journal Articles
• The effect of serum on the transport and phosphorylation of 2‐deoxyglucose by untransformed and transformed mouse 3T3 cells  Journal Articles
• The function of IGF-IR in NNK-mediated lung tumorigenesis  Journal Articles
• The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes  Journal Articles
• The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation  Journal Articles
• The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells  Journal Articles
• The shortest telomeres drive karyotype evolution in transformed cells  Journal Articles
• There is probably a low risk of experiencing a malignant transformation of oral lichen planus  Journal Articles
• Transformation by human adenoviruses  Journal Articles
• Transformation of Merkel cell carcinoma to ganglioneuroblastoma in intracranial metastasis  Journal Articles
• Transformation of rat cells by DNA of human adenovirus 5  Journal Articles
• Transformation of rat embryo fibroblasts by cloned polyoma virus DNA fragments containing only part of the early region.  Journal Articles
• Transformation of rodent cells by DNA extracted from transformation-defective adenovirus mutants  Journal Articles
• Transforming Growth Factor α Localization and Role in Surface Epithelium of Normal Human Ovaries and in Ovarian Carcinoma Cells  Journal Articles
• Treatment and Clinical Outcomes of Patients with Teratoma with Somatic-Type Malignant Transformation: An International Collaboration  Journal Articles
• Tumor antigens of human ad5 in transformed cells and in cells infected with transformation-defective host-range mutants  Journal Articles
• Tumorigenicity of adenovirus-transformed rodent cells is influenced by at least two regions of adenovirus type 12 early region 1A  Journal Articles
• Tumours of the mononuclear phagocyte system: A review of clinical and pathological features  Journal Articles
• Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis  Journal Articles
• Ultrastructure of the sarcomatous component in gliosarcomas.  Journal Articles
• Upregulation of FAM84B during prostate cancer progression  Journal Articles
• YAP: At the crossroad between transformation and tumor suppression  Journal Articles
• hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization  Journal Articles
• miR-1297 is frequently downmodulated in flat epithelial atypia of the breast and promotes mammary neoplastic transformation via EphrinA2 regulation.  Journal Articles
• p73 and p63: Why Do We Still Need Them?  Journal Articles