Cell Transformation, Neoplastic Concept

subject area of

• 65-year-old female with cerebellopontine angle lesion  Academic Article
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Academic Article
• A UV-specific endonucleolytic activity present in human cell extracts  Academic Article
• A plasmid vehicle suitable for the molecular cloning and characterization of mammalian promoters  Academic Article
• A transgenic mouse line harboring a smooth muscle alpha-actin promoter polyomavirus middle T antigen transgene develops an epithelial hyperplasia in the rectum and distal stomach.  Academic Article
• A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis  Academic Article
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Academic Article
• Actions of radiation on living cells in the “post-bystander” era  Academic Article
• Adherence to Guidelines for Surveillance Colonoscopy in Patients with Ulcerative Colitis at a Canadian Quaternary Care Hospital  Academic Article
• Aldehyde dehydrogenase 3A1 associates with prostate tumorigenesis  Academic Article
• An Immunohistological Comparison of Primary Lung Carcinosarcoma and Sarcoma  Academic Article
• An Interactive Web-Based Educational Tool Improves Detection and Delineation of Barrett’s Esophagus–Related Neoplasia  Academic Article
• Apoptosis and other effects of radiation in normal human urothelial cells  Academic Article
• Autologous and Allogeneic Stem-Cell Transplantation for Transformed Follicular Lymphoma: A Report of the Canadian Blood and Marrow Transplant Group  Academic Article
• Basophil production in myeloproliferative disorders: increases during acute blastic transformation of chronic myeloid leukemia  Academic Article
• Biological Activity of Tumor Virus Dna  Academic Article
• Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation  Academic Article
• Borderline mucinous cystic tumor in jejunal pancreatic heterotopia  Academic Article
• Brain Tumor Stem Cells: Identification and Concepts  Academic Article
• Butein impairs the protumorigenic activity of malignant pleural mesothelioma cells  Academic Article
• Cancer stem cells in nervous system tumors  Academic Article
• Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex  Academic Article
• Cellular processes of v-Src transformation revealed by gene profiling of primary cells - Implications for human cancer  Academic Article
• Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5  Academic Article
• Combined analysis of cervical smears. Cytopathology, image cytometry and in situ hybridization.  Academic Article
• Concepts of human leukemic development  Academic Article
• Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.  Academic Article
• Contribution of Electron Microscopy to Understanding Cellular Differentiation in Mesenchymal Tumors of the Gastrointestinal Tract: A Study of 82 Tumors  Academic Article
• Covalently closed circles of human adenovirus DNA are infectious.  Academic Article
• Defective repair of UV-damaged DNA in human tumor and SV40-transformed human cells but not in adenovirus-transformed human cells  Academic Article
• Defective transforming capacity of adenovirus type 5 host-range mutants  Academic Article
• Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions  Academic Article
• Detection of SYT–SSX1/2 fusion transcripts by reverse transcriptase–polymerase chain reaction (RT–PCR) is a valuable diagnostic tool in synovial sarcoma  Academic Article
• Development of transformed characteristics by sheep thyroid cells irradiated as differentiated primary cultures  Academic Article
• Dysplasia to carcinoma transformation in ulcerative colitis  Academic Article
• Evidence for the transmission of neoplastic properties from transformed to normal human stem cells  Academic Article
• Expression of Lethal Mutations Is Suppressed in Neoplastically Transformed Cells and after Treatment of Normal Cells with Carcinogens  Academic Article
• Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells.  Academic Article
• Extracellular Signal-Regulated Kinases Modulate DNA Damage Response - A Contributing Factor to Using MEK Inhibitors in Cancer Therapy  Academic Article
• From Birth Till Death: Neurogenesis, Cell Cycle, and Neurodegeneration  Academic Article
• Functional role of BAALC in leukemogenesis  Academic Article
• GBM secretome induces transient transformation of human neural precursor cells  Academic Article
• GFI1 is required for RUNX1/ETO positive acute myeloid leukemia  Academic Article
• Generation of Murine Xenograft Models of Brain Tumors from Primary Human Tissue for In Vivo Analysis of the Brain Tumor-Initiating Cell  Academic Article
• Growth of 293 Cells in Suspension Culture  Academic Article
• Host-range mutants of adenovirus type 5 defective for growth in HeLa cells  Academic Article
• Human acute myeloid leukemia stem cells  Academic Article
• IQGAP2, A candidate tumour suppressor of prostate tumorigenesis  Academic Article
• Identification of Adenovirus E1A Regions Which Affect MHC Class I Expression and Susceptibility to Cytotoxic T Lymphocytes  Academic Article
• Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.  Academic Article
• Immortalization of mouse neural precursor cells by the c-myc oncogene.  Academic Article
• In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation  Academic Article
• Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1  Academic Article
• Iron incorporation into ferritin and hemoglobin during differentiation of murine erythroleukemia cells  Academic Article
• Lactate-mediated changes in growth morphology and transformation frequency of irradiated C3h cells  Academic Article
• Lethal mutations and genomic instability  Academic Article
• Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer  Academic Article
• Malignant Transformation Within Ovarian Dermoid Cysts  Academic Article
• Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice*  Academic Article
• Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating CellsIn vivo  Academic Article
• Mathematical model for the cancer stem cell hypothesis  Academic Article
• Medulloblastoma stem cells: where development and cancer cross pathways  Academic Article
• MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/β-catenin signaling pathway  Academic Article
• Mitochondria and Cancer: Past, Present, and Future  Academic Article
• Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13  Academic Article
• Modeling the Initiation and Progression of Human Acute Leukemia in Mice  Academic Article
• Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity  Academic Article
• Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15  Academic Article
• NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells  Academic Article
• Nonrandom chromosomal abnormalities in bovine lymphoma  Academic Article
• Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis  Academic Article
• Omics Underpins Novel Clues on VDR Chemoprevention Target in Breast Cancer  Academic Article
• Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis  Academic Article
• Orthotopic, syngeneic mouse model to study the effects of epithelial-stromal interaction  Academic Article
• PKM2 contributes to cancer metabolism  Academic Article
• Pathway Pathology  Academic Article
• Pleuropulmonary blastoma  Academic Article
• Pluripotent human stem cell lines: what we can learn about cancer initiation  Academic Article
• Polyomavirus-plasmid recombinants capable of replicating have an enhanced transforming potential.  Academic Article
• Prognostic implications of basophil differentiation in chronic myeloid leukemia  Academic Article
• Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma  Academic Article
• Progression toward malignancy of hamartomas in a patient with Peutz-Jeghers syndrome: case report and literature review.  Academic Article
• Proliferative verrucous leukoplakia and erythroplakia are probably the disorders with the highest rate of malignant transformation  Academic Article
• Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53  Academic Article
• Protooncogene expression and the clinical characteristics of acute nonlymphocytic leukemia: A Leukemia Intergroup pilot study  Academic Article
• Radiation-induced bystander effects — implications for cancer  Academic Article
• Regulation of gene expression in oncogenically transformed cells  Academic Article
• Relation of Herpes Simplex Viruses to Human Malignancies  Academic Article
• Repression of quiescence-specific polypeptides in chicken heart mesenchymal cells transformed by Rous sarcoma virus.  Academic Article
• Reproducibility and variability of the rectal mucosal proliferation index using proliferating cell nuclear antigen immunohistochemistry.  Academic Article
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Academic Article
• Reversibility and recurrence of IGF-IR-induced mammary tumors  Academic Article
• S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia  Academic Article
• SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells  Academic Article
• Simultaneous or sequential expression of lymphoid and myeloid phenotypes in acute leukemia  Academic Article
• Size and location of the transforming region in human adenovirus type 5 DNA  Academic Article
• Studies on In Vitro Transformation by DNA and DNA Fragments of Human Adenoviruses and Simian Virus 40  Academic Article
• Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin  Academic Article
• Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells  Academic Article
• Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction  Academic Article
• Telomerase activity associated with acquisition of malignancy in human colorectal cancer.  Academic Article
• Telomerase, Cell Immortality, and Cancer  Academic Article
• Telomere maintenance in tumour cells.  Academic Article
• Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.  Academic Article
• The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB  Academic Article
• The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation  Academic Article
• The Influence of Lethal Mutations on the Quantification of Radiation Transformation Frequencies  Academic Article
• The amino terminus of polyomavirus middle T antigen is required for transformation  Academic Article
• The effect of radiation in combination with carcinogens on the growth of normal urothelium in explant culture  Academic Article
• The effect of serum on the transport and phosphorylation of 2-deoxyglucose by untransformed and transformed mouse 3T3 cells  Academic Article
• The function of IGF-IR in NNK-mediated lung tumorigenesis  Academic Article
• The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes  Academic Article
• The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation  Academic Article
• The role of O⁶-alkylguanine-DNA alkyltransferase in protecting Rat4 cells against the mutagenic effects of O⁶-substituted guanine residues incorporated in codon 12 of the H-ras gene  Academic Article
• The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells  Academic Article
• The shortest telomeres drive karyotype evolution in transformed cells  Academic Article
• There is probably a low risk of experiencing a malignant transformation of oral lichen planus  Academic Article
• Transformation by human adenoviruses  Academic Article
• Transformation of Merkel cell carcinoma to ganglioneuroblastoma in intracranial metastasis  Academic Article
• Transformation of rat cells by DNA of human adenovirus 5  Academic Article
• Transformation of rat embryo fibroblasts by cloned polyoma virus DNA fragments containing only part of the early region.  Academic Article
• Transformation of rodent cells by DNA extracted from transformation-defective adenovirus mutants  Academic Article
• Transforming Growth Factor α Localization and Role in Surface Epithelium of Normal Human Ovaries and in Ovarian Carcinoma Cells  Academic Article
• Treatment and Clinical Outcomes of Patients with Teratoma with Somatic-Type Malignant Transformation: An International Collaboration  Academic Article
• Tumor antigens of human ad5 in transformed cells and in cells infected with transformation-defective host-range mutants  Academic Article
• Tumorigenicity of adenovirus-transformed rodent cells is influenced by at least two regions of adenovirus type 12 early region 1A  Academic Article
• Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis  Academic Article
• Ultrastructure of the sarcomatous component in gliosarcomas.  Academic Article
• Upregulation of FAM84B during prostate cancer progression  Academic Article
• YAP: At the crossroad between transformation and tumor suppression  Academic Article
• hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization  Academic Article
• p73 and p63: Why Do We Still Need Them?  Academic Article