Journal article
Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5
Abstract
Human embryonic kidney cells have been transformed by exposing cells to sheared fragments of adenovirus type 5 DNA. The transformed cells (designated 293 cells) exhibited many of the characteristics of transformation including the elaboration of a virus-specific tumour antigen. Analysis of the polypeptides synthesized in the 293 cells by labelling with 35S-methionine and SDS PAGE showed a variable pattern of synthesis, different in a number of …
Authors
Graham FL; Smiley J; Russell WC; Nairn R
Journal
Journal of General Virology, Vol. 36, No. 1, pp. 59–72
Publisher
Microbiology Society
Publication Date
July 1, 1977
DOI
10.1099/0022-1317-36-1-59
ISSN
0022-1317