Journal article
Defective transforming capacity of adenovirus type 5 host-range mutants
Abstract
Host-range (hr) mutants of human adenovirus type 5 (Ad 5), selected for their ability to grow preferentially on transformed human embryo kidney cells (293 cells) and shown to fall into two complementation groups (I and II), have been tested for ability to transform rat embryo, rat embryo brain, and baby rat kidney cells. When embryo or embryo brain cells were used, mutants of both complementation groups either failed to transform or transformed …
Authors
Graham FL; Harrison T; Williams J
Journal
Virology, Vol. 86, No. 1, pp. 10–21
Publisher
Elsevier
Publication Date
5 1978
DOI
10.1016/0042-6822(78)90003-x
ISSN
0042-6822