Piperidines
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2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty Academic Article
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2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty Academic Article
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2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis Academic Article
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A Comparison of HU12 and HU13 Utility Scores in Alzheimer's Disease Academic Article
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A Phase I Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer Academic Article
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A Phase I study of cyclin-dependent kinase inhibitor, AT7519, in patients with advanced cancer: NCIC Clinical Trials Group IND 177 Academic Article
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A Prospective Economic Analysis of Early Outcome Data From the Alliance A041202/ CCTG CLC.2 Randomized Phase III Trial Of Bendamustine-Rituximab Compared With Ibrutinib-Based Regimens in Untreated Older Patients With Chronic Lymphocytic Leukemia Academic Article
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A macrophage-stimulating compound from a screen of microbial natural products Academic Article
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A phase II study of ZD6474 (Zactima™), a selective inhibitor of VEGFR and EGFR tyrosine kinase in patients with relapsed multiple myeloma—NCIC CTG IND.145 Academic Article
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A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naïve castration-resistant prostate cancer Academic Article
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Alkaloids Modulate Motility, Biofilm Formation and Antibiotic Susceptibility of Uropathogenic Escherichia coli Academic Article
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Antagonism of nociceptive responses of cat spinal dorsal horn neurons in vivo by the NK-1 receptor antagonists CP-96,345 and CP-99,994, but not by CP-96,344 Academic Article
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Assessment of Alectinib vs Ceritinib in ALK-Positive Non–Small Cell Lung Cancer in Phase 2 Trials and in Real-world Data Academic Article
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Ava[l-Pro9,N-MeLeu10] Substance P(7-11) (GR 73632) and Sar9, Met(O2)11Increase Distention-Induced Peristalsis through Activation of Neurokinin-1 Receptors on Smooth Muscle and Interstitial Cells of Cajal Academic Article
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Biosynthesis of the Piperidine Nucleus Academic Article
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Biosynthesis of the piperidine nucleus. Incorporation of chirally labeled cadaverine-1-3H Academic Article
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Bone marrow-derived mast cells in mice respond in co-culture to scorpion venom activation of superior cervical ganglion neurites according to level of expression of NK-1 receptors Academic Article
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Bruton’s tyrosine kinase Inhibitors and Cardiotoxicity: More Than Just Atrial Fibrillation Academic Article
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Cannabinoids Reveal Separate Controls for Whisking Amplitude and Timing in Rats Academic Article
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Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. Academic Article
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Cardiovascular Risk Associated With Ibrutinib Use in Chronic Lymphocytic Leukemia: A Population-Based Cohort Study Academic Article
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Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis Academic Article
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Cardiovascular and Renal Actions of the EndothelinB Receptor in Pigs Academic Article
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Characterization of atrial fibrillation adverse events reported in ibrutinib randomized controlled registration trials Academic Article
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Cisapride improves gastric emptying in mechanically ventilated, critically ill patients. A randomized, double-blind trial. Academic Article
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Cisapride: a review of the evidence supporting its use in premature infants with feeding intolerance. Academic Article
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Clinical Trials in Cognitively Impaired Older Adults: Home versus Clinic Assessments Academic Article
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Comparison of the effects of neurokinin-3 receptor blockade on two forms of slow synaptic transmission in myenteric AH neurons Academic Article
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Current Pharmacologic Treatment of Dementia: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians Academic Article
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Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer Academic Article
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Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data Academic Article
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Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA Academic Article
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Do H2 receptor antagonists have to be given at night? A study of the antisecretory profile of SKF 94482, a new H2 receptor antagonist which has a profound effect on daytime acidity. Academic Article
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Donepezil and rivastigmine in the treatment of Alzheimer's disease: a best-evidence synthesis of the published data on their efficacy and cost-effectiveness Academic Article
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Donepezil-associated manic episode with psychotic features: a case report and review of the literature Academic Article
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ERG K+ currents regulate pacemaker activity in ICC Academic Article
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Economic Evaluation of Donepezil for the Treatment of Alzheimer's Disease in Canada Academic Article
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Effect of tofacitinib withdrawal and re-treatment on patient-reported outcomes: results from a Phase 3 study in patients with moderate to severe chronic plaque psoriasis Academic Article
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Effectiveness of Cholinesterase Inhibitors and Memantine for Treating Dementia: Evidence Review for a Clinical Practice Guideline Academic Article
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Effects of chronic brofaromine administration on biogenic amines including sulphatoxymelatonin and acid metabolites in patients with bulimia nervosa Academic Article
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Effects of ibrutinib on in vitro platelet aggregation in blood samples from healthy donors and donors with platelet dysfunction Academic Article
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Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study. Academic Article
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Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis Academic Article
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Efficacy and safety of donepezil in patients with more severe Alzheimer's disease: a subgroup analysis from a randomized, placebo-controlled trial Academic Article
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Efficacy and safety of tofacitinib dose de-escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open Academic Article
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Efficacy of Donepezil on Behavioral Symptoms in Patients With Moderate to Severe Alzheimer's Disease Academic Article
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Electrophysiological Evidence That Neurokinin A Acts Via NK-1 Receptors in the Cat Dorsal Horn Academic Article
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Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret Academic Article
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Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal Academic Article
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Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique Academic Article
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Evidence for Tonic Activation of NK-1 Receptors during the Second Phase of the Formalin Test in the Rat Academic Article
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Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma Conference Paper
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Flavopiridol Sensitivity of Cancer Cells Isolated from Ascites and Pleural Fluids Academic Article
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Flavopiridol in Untreated or Relapsed Mantle-Cell Lymphoma: Results of a Phase II Study of the National Cancer Institute of Canada Clinical Trials Group Academic Article
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Functional characterization of estrogen receptor subtypes, ERα and ERβ, mediating vitellogenin production in the liver of rainbow trout Academic Article
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Functional subtyping of muscarinic receptors on canine esophageal mucosa Academic Article
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Growth inhibition of prostate cancer xenografts by halofuginone Academic Article
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High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells Academic Article
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Histrionicotoxin: Effects on Some Central and Peripheral Excitable Cells Academic Article
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Hsp72 preserves muscle function and slows progression of severe muscular dystrophy Academic Article
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INHIBITION OF WILMS TUMOR XENOGRAFT PROGRESSION BY HALOFUGINONE IS ACCOMPANIED BY ACTIVATION OF WT-1 GENE EXPRESSION Conference Paper
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Ibrutinib combined with bendamustine and rituximab compared with placebo, bendamustine, and rituximab for previously treated chronic lymphocytic leukaemia or small lymphocytic lymphoma (HELIOS): a randomised, double-blind, phase 3 study Academic Article
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Ibrutinib for bridging to allogeneic hematopoietic cell transplantation in patients with chronic lymphocytic leukemia or mantle cell lymphoma: a study by the EBMT Chronic Malignancies and Lymphoma Working Parties Academic Article
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Identification of both NK1 and NK2 receptors in guinea-pig airways Academic Article
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Incidence of and risk factors for major haemorrhage in patients treated with ibrutinib: An integrated analysis Academic Article
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Incomplete Cross-Resistance Between Taxanes for Advanced Urothelial Carcinoma: Implications for Clinical Practice and Trial Design Academic Article
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Incorporating Fecal Calprotectin Into Clinical Practice for Patients With Moderate-to-Severely Active Ulcerative Colitis Treated With Biologics or Small-Molecule Inhibitors Academic Article
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Induction with sevoflurane-remifentanil is comparable to propofol-fentanyl-rocuronium in PONV after laparoscopic surgery Academic Article
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Inhibition of Microsurgical Thrombosis by the Platelet Glycoprotein IIb/IIIa Antagonist SR121566A Academic Article
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Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect Academic Article
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Intravenous anaesthesia with remifentanil in a preterm infant Academic Article
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Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs Academic Article
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Joint cholinergic-serotonergic control of neocortical and hippocampal electrical activity in relation to behavior: Effects of scopolamine, ditran, trifluoperazine and amphetamine Academic Article
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Letter: corticosteroid use alongside tofacitinib in OCTAVE Open. Authors' reply Academic Article
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Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia Academic Article
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Maintenance therapy: Is there still a place for antireflux surgery? Academic Article
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Multidisciplinary Real-World Experience With Bilastine, a Second Generation Antihistamine Academic Article
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NK2 receptors mediate plasma extravasation in guinea-pig lower airways Academic Article
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NK1and NK2Receptors Mediate Tachykinin and Resiniferatoxin-induced Bronchospasm in Guinea Pigs Academic Article
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Network meta-analysis of therapies for previously untreated advanced BRAF-mutated melanoma Academic Article
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Neurokinin (NK2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea Academic Article
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Neurokinin receptors subserving plasma extravasation in guinea pig airways Academic Article
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Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain Academic Article
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Patient Satisfaction with Awake Craniotomy for Tumor Surgery: A Comparison of Remifentanil and Fentanyl in Conjunction with Propofol Academic Article
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Peroxide sensitivity of endothelin responses in coronary artery smooth muscle: ET(A) vs. ET(B) pathways. Academic Article
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Phase II Study of Vandetanib or Placebo in Small-Cell Lung Cancer Patients After Complete or Partial Response to Induction Chemotherapy With or Without Radiation Therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20 Academic Article
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Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma Academic Article
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Physician- and Patient-reported Effectiveness Are Similar for Tofacitinib and TNFi in Rheumatoid Arthritis: Data From a Rheumatoid Arthritis Registry Academic Article
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Pre- and postjunctional muscarinic receptors in canine bronchi Academic Article
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Pre-prandial vs. post-prandial capillary glucose measurements as targets for repaglinide dose titration in people with diet-treated or metformin-treated Type 2 diabetes: a randomized controlled clinical trial Academic Article
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Prevalence of endoscopic improvement and remission according to patient-reported outcomes in ulcerative colitis Academic Article
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Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells Academic Article
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Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study Academic Article
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Recent advances in the treatment of uremic pruritus Academic Article
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Remifentanil for endotracheal intubation in neonates: a randomised controlled trial Academic Article
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Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial Academic Article
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Safety Analysis of Four Randomized Controlled Studies of Ibrutinib in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Mantle Cell Lymphoma Academic Article
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Sedation, Analgesia, and Anaesthesia Variability in Laboratory-Based Cardiac Procedures: An International Survey Academic Article
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Sensitization of enteric reflexes in the rat colon in vitro Academic Article
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Substance P-induced histamine release in tracheally perfused guinea pig lungs Academic Article
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Systemic Exposure of Rituximab Increased by Ibrutinib: Pharmacokinetic Results and Modeling Based on the HELIOS Trial Academic Article
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Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs. Academic Article
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Target-Controlled Dosing of Remifentanil During Cardiac Surgery Reduces Postoperative Hyperalgesia Academic Article
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The Single-Subject Randomized Trial Academic Article
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The effect of a selective 5-HT2 antagonist, ketanserin, on the pulmonary responses to Escherichia coli endotoxin Academic Article
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The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1receptor antagonism ? or inverse agonism ? as potential obesity treatment and other therapeutic use Academic Article
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The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli Academic Article
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The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain Academic Article
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The response of the lamb ductus arteriosus to endothelin: developmental changes and influence of light Academic Article
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The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis Academic Article
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The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors Academic Article
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Therapy of Angina Pectoris with Low-Dose Perhexiline Academic Article
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Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty‐Four–Month, Phase
III
Study Academic Article
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Treatment of estrogen deficiency symptoms in women surviving breast cancer. Part 5: Selective estrogen receptor modulators and hormone replacement therapy. Proceedings of a conference. Charlottesville, Virginia, USA. September 21-23, 1997. Conference Paper
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Treatment of estrogen deficiency symptoms in women surviving breast cancer. Part 6: Executive summary and consensus statement. Proceedings of a conference held at Boar's Head Inn, Charlottesville, Virginia, September 21-23, 1997. Conference Paper
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Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine, and rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma Academic Article
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Vascular Endothelial Growth Factor Concentration as a Predictive Marker: Ready for Primetime? Academic Article