Piperidines Concept

subject area of

• 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty  Journal Articles
• 2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty  Journal Articles
• 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis  Journal Articles
• A Comparison of HU12 and HU13 Utility Scores in Alzheimer's Disease  Journal Articles
• A Phase I Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer  Journal Articles
• A Phase I study of cyclin-dependent kinase inhibitor, AT7519, in patients with advanced cancer: NCIC Clinical Trials Group IND 177  Journal Articles
• A macrophage-stimulating compound from a screen of microbial natural products  Journal Articles
• A multinomial Phase II study of lonafarnib (SCH 66336) in patients with refractory urothelial cancer☆  Journal Articles
• A phase II study of ZD6474 (Zactima™), a selective inhibitor of VEGFR and EGFR tyrosine kinase in patients with relapsed multiple myeloma—NCIC CTG IND.145  Journal Articles
• A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naïve castration-resistant prostate cancer  Journal Articles
• Actions of the sympathomimetic bronchodilator, rimiterol (R798), on the cardiovascular, respiratory and skeletal muscle systems of the anaesthetized cat.  Journal Articles
• Alkaloids Modulate Motility, Biofilm Formation and Antibiotic Susceptibility of Uropathogenic Escherichia coli  Journal Articles
• Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes  Journal Articles
• Angiotensin-Converting Enzyme Inhibitor Use and Major Cardiovascular Outcomes in Type 2 Diabetes Mellitus Treated With the Dipeptidyl Peptidase 4 Inhibitor Alogliptin  Journal Articles
• Antagonism of nociceptive responses of cat spinal dorsal horn neurons in vivo by the NK-1 receptor antagonists CP-96,345 and CP-99,994, but not by CP-96,344  Journal Articles
• Assessment of Alectinib vs Ceritinib in ALK-Positive Non–Small Cell Lung Cancer in Phase 2 Trials and in Real-world Data  Journal Articles
• Ava[l-Pro⁹,N-MeLeu10] Substance P(7-11) (GR 73632) and Sar⁹, Met(O₂)¹¹Increase Distention-Induced Peristalsis through Activation of Neurokinin-1 Receptors on Smooth Muscle and Interstitial Cells of Cajal  Journal Articles
• Biosynthesis of the Piperidine Nucleus  Journal Articles
• Bone marrow-derived mast cells in mice respond in co-culture to scorpion venom activation of superior cervical ganglion neurites according to level of expression of NK-1 receptors  Journal Articles
• Bruton’s tyrosine kinase (BTK) inhibitors alter blood glucose and insulin in obese mice but reduce inflammation independent of BTK  Journal Articles
• Bruton’s tyrosine kinase Inhibitors and Cardiotoxicity: More Than Just Atrial Fibrillation  Journal Articles
• CD206⁺macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis  Journal Articles
• Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.  Journal Articles
• Cardiovascular Mortality in Patients With Type 2 Diabetes and Recent Acute Coronary Syndromes From the EXAMINE Trial  Journal Articles
• Cardiovascular Risk Associated With Ibrutinib Use in Chronic Lymphocytic Leukemia: A Population-Based Cohort Study  Journal Articles
• Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis  Journal Articles
• Cardiovascular and Renal Actions of the EndothelinB Receptor in Pigs  Journal Articles
• Cisapride improves gastric emptying in mechanically ventilated, critically ill patients. A randomized, double-blind trial.  Journal Articles
• Cisapride: a review of the evidence supporting its use in premature infants with feeding intolerance.  Journal Articles
• Clinical Trials in Cognitively Impaired Older Adults: Home versus Clinic Assessments  Journal Articles
• Comparative Efficacy of Infliximab Versus Tofacitinib for Inducing Remission in Biologic Naive Ulcerative Colitis: A Propensity Matched Study  Journal Articles
• Comparison of the effects of neurokinin-3 receptor blockade on two forms of slow synaptic transmission in myenteric AH neurons  Journal Articles
• Current Pharmacologic Treatment of Dementia: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians  Journal Articles
• Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer  Journal Articles
• Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data  Journal Articles
• Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA  Journal Articles
• Do H2 receptor antagonists have to be given at night? A study of the antisecretory profile of SKF 94482, a new H2 receptor antagonist which has a profound effect on daytime acidity.  Journal Articles
• Donepezil-associated manic episode with psychotic features: a case report and review of the literature  Journal Articles
• ERG K⁺ currents regulate pacemaker activity in ICC  Journal Articles
• Economic Evaluation of Donepezil for the Treatment of Alzheimer's Disease in Canada  Journal Articles
• Effect of tofacitinib withdrawal and re‐treatment on patient‐reported outcomes: results from a Phase 3 study in patients with moderate to severe chronic plaque psoriasis  Journal Articles
• Effectiveness of Cholinesterase Inhibitors and Memantine for Treating Dementia: Evidence Review for a Clinical Practice Guideline  Journal Articles
• Effects of chronic brofaromine administration on biogenic amines including sulphatoxymelatonin and acid metabolites in patients with bulimia nervosa  Journal Articles
• Effects of ibrutinib on in vitro platelet aggregation in blood samples from healthy donors and donors with platelet dysfunction  Journal Articles
• Effects of ranitidine and cisapride on acid reflux and oesophageal motility in patients with reflux oesophagitis: a 24 hour ambulatory combined pH and manometry study.  Journal Articles
• Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis  Journal Articles
• Efficacy and safety of donepezil in patients with more severe Alzheimer's disease: a subgroup analysis from a randomized, placebo‐controlled trial  Journal Articles
• Efficacy and safety of tofacitinib dose de‐escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open  Journal Articles
• Efficacy of Donepezil on Behavioral Symptoms in Patients With Moderate to Severe Alzheimer's Disease  Journal Articles
• Electrophysiological Evidence That Neurokinin A Acts Via NK‐1 Receptors in the Cat Dorsal Horn  Journal Articles
• Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret  Journal Articles
• Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal  Journal Articles
• Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique  Journal Articles
• Evidence for Tonic Activation of NK-1 Receptors during the Second Phase of the Formalin Test in the Rat  Journal Articles
• Flavopiridol Sensitivity of Cancer Cells Isolated from Ascites and Pleural Fluids  Journal Articles
• Flavopiridol in Untreated or Relapsed Mantle-Cell Lymphoma: Results of a Phase II Study of the National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• Functional characterization of estrogen receptor subtypes, ERα and ERβ, mediating vitellogenin production in the liver of rainbow trout  Journal Articles
• Functional subtyping of muscarinic receptors on canine esophageal mucosa  Journal Articles
• Growth inhibition of prostate cancer xenografts by halofuginone*†  Journal Articles
• Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial  Journal Articles
• High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells  Journal Articles
• Histrionicotoxin: Effects on Some Central and Peripheral Excitable Cells  Journal Articles
• Hsp72 preserves muscle function and slows progression of severe muscular dystrophy  Journal Articles
• INHIBITION OF WILMS TUMOR XENOGRAFT PROGRESSION BY HALOFUGINONE IS ACCOMPANIED BY ACTIVATION OF WT-1 GENE EXPRESSION  Conferences
• Ibrutinib for bridging to allogeneic hematopoietic cell transplantation in patients with chronic lymphocytic leukemia or mantle cell lymphoma: a study by the EBMT Chronic Malignancies and Lymphoma Working Parties  Journal Articles
• Identification of both NK₁ and NK₂ receptors in guinea‐pig airways  Journal Articles
• Incomplete Cross-Resistance Between Taxanes for Advanced Urothelial Carcinoma: Implications for Clinical Practice and Trial Design  Journal Articles
• Incorporating Fecal Calprotectin Into Clinical Practice for Patients With Moderate-to-Severely Active Ulcerative Colitis Treated With Biologics or Small-Molecule Inhibitors  Journal Articles
• Induction with sevoflurane-remifentanil is comparable to propofol-fentanyl-rocuronium in PONV after laparoscopic surgery  Journal Articles
• Inhibition of Microsurgical Thrombosis by the Platelet Glycoprotein IIb/IIIa Antagonist SR121566A  Journal Articles
• Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect  Journal Articles
• Intravenous anaesthesia with remifentanil in a preterm infant  Journal Articles
• Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs  Journal Articles
• Letter: corticosteroid use alongside tofacitinib in OCTAVE Open. Authors' reply  Journal Articles
• Maintenance therapy: Is there still a place for antireflux surgery?  Journal Articles
• Multidisciplinary Real-World Experience With Bilastine, a Second Generation Antihistamine  Journal Articles
• NK₁and NK₂Receptors Mediate Tachykinin and Resiniferatoxin-induced Bronchospasm in Guinea Pigs  Journal Articles
• NK₂ receptors mediate plasma extravasation in guinea‐pig lower airways  Journal Articles
• Network meta-analysis of therapies for previously untreated advanced BRAF-mutated melanoma  Journal Articles
• Neurokinin (NK₂) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea  Journal Articles
• Neurokinin receptors subserving plasma extravasation in guinea pig airways  Journal Articles
• Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P  Journal Articles
• Nociceptive response to innocuous mechanical stimulation is mediated via myelinated afferents and NK-1 receptor activation in a rat model of neuropathic pain  Journal Articles
• PREJUNCTIONAL AND POSTJUNCTIONAL MUSCARINIC RECEPTORS IN CANINE BRONCHI  Journal Articles
• PROLIFERATION OF GUINEA-PIG TRACHEAL EPITHELIAL-CELLS IN COCULTURE WITH RAT DORSAL-ROOT GANGLION NEURAL CELLS  Journal Articles
• Patient Satisfaction with Awake Craniotomy for Tumor Surgery: A Comparison of Remifentanil and Fentanyl in Conjunction with Propofol  Journal Articles
• Peroxide sensitivity of endothelin responses in coronary artery smooth muscle: ET(A) vs. ET(B) pathways.  Journal Articles
• Phase II Study of Vandetanib or Placebo in Small-Cell Lung Cancer Patients After Complete or Partial Response to Induction Chemotherapy With or Without Radiation Therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20  Journal Articles
• Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma  Journal Articles
• Physician- and Patient-reported Effectiveness Are Similar for Tofacitinib and TNFi in Rheumatoid Arthritis: Data From a Rheumatoid Arthritis Registry  Journal Articles
• Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages.  Journal Articles
• Pre- and postjunctional muscarinic receptors in canine bronchi  Journal Articles
• Prevalence of endoscopic improvement and remission according to patient‐reported outcomes in ulcerative colitis  Journal Articles
• Pre‐prandial vs. post‐prandial capillary glucose measurements as targets for repaglinide dose titration in people with diet‐treated or metformin‐treated Type 2 diabetes: a randomized controlled clinical trial  Journal Articles
• Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells  Journal Articles
• REMIT-UC: Real-World Effectiveness and Safety of Tofacitinib for Moderate-to-Severely Active Ulcerative Colitis  Journal Articles
• Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study  Journal Articles
• Recent advances in the treatment of uremic pruritus  Journal Articles
• Remifentanil for endotracheal intubation in neonates: a randomised controlled trial  Journal Articles
• Resolution of rectal bleeding by day 7 in acute severe ulcerative colitis is prognostic for post-discharge corticosteroid free clinical remission and endoscopic improvement  Journal Articles
• Sedation, Analgesia, and Anaesthesia Variability in Laboratory-Based Cardiac Procedures: An International Survey  Journal Articles
• Sensitization of enteric reflexes in the rat colon in vitro  Journal Articles
• Substance P-induced histamine release in tracheally perfused guinea pig lungs  Journal Articles
• Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs.  Journal Articles
• Target-Controlled Dosing of Remifentanil During Cardiac Surgery Reduces Postoperative Hyperalgesia  Journal Articles
• The Neurokinin-1 Receptor Antagonist Orvepitant Is a Novel Antitussive Therapy for Chronic Refractory Cough  Journal Articles
• The Single-Subject Randomized Trial  Journal Articles
• The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21.  Journal Articles
• The current role of Tofacitinib in acute severe ulcerative colitis in adult patients: A systematic review  Journal Articles
• The effect of a selective 5‐HT₂ antagonist, ketanserin, on the pulmonary responses to Escherichia coli endotoxin  Journal Articles
• The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB₁receptor antagonism ? or inverse agonism ? as potential obesity treatment and other therapeutic use  Journal Articles
• The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli  Journal Articles
• The response of the lamb ductus arteriosus to endothelin: developmental changes and influence of light  Journal Articles
• The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis  Journal Articles
• The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors  Journal Articles
• Therapy of Angina Pectoris with Low-Dose Perhexiline  Journal Articles
• Tofacitinib Persistence in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study.  Journal Articles
• Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty‐Four–Month, Phase III Study  Journal Articles
• USE OF CUMULATIVE DOSE-RESPONSE CURVES IN POTENCY COMPARISONS OF SYMPATHOMIMETIC AMINES ON PULMONARY RESISTANCE IN ANAESTHETIZED CATS  Journal Articles
• VITT-like Monoclonal Gammopathy of Thrombotic Significance.  Journal Articles
• Vascular Endothelial Growth Factor Concentration as a Predictive Marker: Ready for Primetime?  Journal Articles